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Start Over Author "Galluzzi, Lorenzo" Topic immunogenic cell death Journal trends in cell biology

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1 results on '"Galluzzi, Lorenzo"'

1. TREX1 Cuts Down on Cancer Immunogenicity.

Author

Yamazaki, Takahiro and Galluzzi, Lorenzo

Subjects
*IMMUNOGENETICS, *EXONUCLEASES, *CANCER cells, *RADIOTHERAPY, *IMMUNE response
Abstract

Demaria and colleagues have recently identified three prime repair exonuclease 1 (TREX1) as a key determinant for the limited immunogenicity of cancer cells responding to single high-dose radiation. TREX1 stands out as a promising target for the development of novel strategies to boost anticancer immune responses driven by radiation therapy (RT). [ABSTRACT FROM AUTHOR]

Published
2017
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