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Start Over Author "Quezada, Sergio A." Topic antineoplastic agents Journal trends in immunology

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1. Fcγ-receptor tag team boosts anti-tumor immunity.

Author

Arce Vargas, Frederick and Quezada, Sergio A.

Subjects
*FC receptors, *ANTINEOPLASTIC agents, *MONOCLONAL antibodies, *ANTIBODY-dependent cell cytotoxicity, *ANTIGEN presenting cells, *GENE expression
Abstract

Anti-tumor monoclonal antibodies eliminate tumor cells through different mechanisms including antibody-mediated cell cytotoxicity and generation of long-term anti-tumor T cell responses. In a recent publication, DiLillo and Ravetch demonstrate how this vaccinal effect is mediated by engagement of Fcγ receptors expressed on antigen-presenting cells. [ABSTRACT FROM AUTHOR]

Published
2015
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