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In this article we will see that depending on the context and diversity, discovering and teaching in science, should have an Intercultural look. The final objective of the so-called exact sciences, practically mostly, you could say it's the same. This objective would be to know and understand the secrets it holds the universe. But how do we discover? and how do we learn the knowledge that are already found?, we propose that this path should be intercultural. In this paper, first we will try to adopt and / or assume a definition for the words of Knowledge, Education, Science and Interculturality; because they are words that have much theoretical debate, and if we do not assume some definition for them, we will not reach to any goal. Then we will prove that interculturality must be present at the time of doing science and teaching it, for which purpose, we will find support primarily with studies of neuroscience, then, with the meaningful learning theory of Ausubel, with Piaget that gives importance to the prior knowledge of the learner, by Watson, Vygotsky, etc. Even we give an ancient example, in which this knowledge has already been used with good results; we talk about education in times of the Incas. This is a clear example that interculturality should be applied to teaching and conducting science. [ABSTRACT FROM AUTHOR]