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Epidermal growth factor is a potent stimulator of the growth of epithelial and mesenchymal cells. In this study the effect of epidermal growth factor on the cells of developing mice intestine and on the serum zinc concentrations were assessed. Higher serum zinc concentrations (840.21 +/- 187.82 mg/dl) were found in the mice given epidermal growth factor (n: 10) as compared to the values obtained in the controls (347.55 +/- 108.88 mg/dl), (n: 12) (p less than 0.05).

We report a case of mucopolysaccharidoses I with severe cardiac involvement, which was diagnosed on the basis of clinical and laboratory findings even though, symptoms begin to occur in mucopolysaccharidoses after the first year of life. In our case cardiac failure occurred in the third month of life, which resulted in the patient's death after one month.