1. A New Ultrasonographic "Fluttering Sign" for Hepatic Hemangioma.
- Author
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Kobayashi N, Iijima H, Tada T, Shibata Y, Nishimura T, Kumada T, Hashimoto M, Higashiura A, Yoshida M, Nishimura J, Aizawa N, Ikeda N, Takashima T, Takata R, Nishikawa H, Iwata Y, Enomoto H, Hirota S, and Hatano E
- Subjects
- Aged, Contrast Media, Female, Hemangioma pathology, Humans, Liver Neoplasms pathology, Male, Middle Aged, Retrospective Studies, Tumor Burden, Hemangioma diagnostic imaging, Liver Neoplasms diagnostic imaging, Ultrasonography
- Abstract
The aim of the study described here was to clarify the diagnostic value of the fluttering sign, a new sign that characterizes hepatic hemangiomas in gray-scale ultrasonography (US). It refers to a phenomenon in which the speckled echogenicity inside the hemangioma changes continuously and seems to be moving. A total of 172 hemangiomas diagnosed with contrast-enhanced US were evaluated. The fluttering sign was found in 123 of 172 hemangiomas (71.5%). Its prevalence was significantly higher than that of the marginal strong echo (89/172, 51.7%, p < 0.001), posterior acoustic enhancement (103/172, 59.9%, p = 0.031) and chameleon sign (100/172, 58.1%, p = 0.013). In addition, the fluttering sign was observed significantly more frequently in mixed or hypo-echoic tumors than in hyper-echoic tumors (p < 0.001), relatively large tumors (p < 0.001) and tumors that were less than 5 cm from the body surface (p = 0.015). The fluttering sign in gray-scale US has great potential to be a new complementary sign for the diagnosis of hemangioma., Competing Interests: Conflict of interest disclosure The authors have no conflicts of interest to declare., (Copyright © 2020 The Authors. Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
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