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This article discusses a study that aimed to establish a correlation between sonographic and histopathologic patterns in severe Human Cytomegalovirus (HCMV)-related lesions in fetuses. The researchers collected cases of fetuses with HCMV and severe neurosonographic alterations and examined the brain tissue samples obtained from postmortem examinations. They found that there were two main periventricular sonographic patterns, which corresponded to two different histopathologic patterns. The study suggests a relationship between these patterns and calls for further investigations to understand the timeline, development, and neurological correlations of these lesions in newborns. [Extracted from the article]