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Start Over Author "Yorito Nose" Journal urology case reports
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1. A rare case of de novo large cell neuroendocrine carcinoma of the prostate with long-term survival after cystoprostatectomy and androgen deprivation

Author

Yukio Homma, Haruki Kume, Yukiko Kishida, Yorito Nose, Jimpei Miyakawa, Koichi Tamura, Motofumi Suzuki, Shoujiroh Morinaga, Kaori Endo, and Toshikazu Sato

Subjects
medicine.drug_class, business.industry, Urology, medicine.medical_treatment, medicine.disease, Androgen, Small-cell carcinoma, digestive system diseases, Cystoprostatectomy, Androgen deprivation therapy, 03 medical and health sciences, 0302 clinical medicine, medicine.anatomical_structure, Prostate, 030220 oncology & carcinogenesis, medicine, Cancer research, Adenocarcinoma, 030211 gastroenterology & hepatology, Large-cell neuroendocrine carcinoma, Radical surgery, business
Abstract

More than 95% of prostate cancers are adenocarcinoma, and neuroendocrine carcinomas (NECs) are very rare, representing less than 1% of prostate cancers. Among NECs of the prostate including small cell carcinoma (SmCC), carcinoids, and large cell neuroendocrine carcinoma (LCNEC), LCNEC is extremely rare. Only 15 cases have been reported to date and their prognoses were very poor. Here, we report a patient with de novo LCNEC of the prostate that was successfully treated with radical surgery and adjuvant androgen deprivation therapy (ADT).

Published
2018

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