1. Establishment of Asia-Pacific Network for Enterovirus Surveillance
- Author
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Ya-Yen Chen, Yoke Fun Chan, Veasna Duong, Wan Yu Chung, Shu Ting Luo, Philippe Dussart, Huu Khanh Truong, Mu-Lin Chiu, Nguyen Thi Thanh Thao, Mong How Ooi, David Perera, Min-Shi Lee, National Health Research Institutes [Taiwan] (NHRI), Unité de Virologie / Virology Unit [Phnom Penh], Institut Pasteur du Cambodge, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), University of Malaya [Kuala Lumpur, Malaisie], Universiti Malaysia Sarawak (UNIMAS), Sarawak General Hospital [Kuching, Sarawak, Malaysia], Institut Pasteur d'Ho Chi Minh Ville, Réseau International des Instituts Pasteur (RIIP), Children's Hospital No.1 [Ho Chi Minh City], and This project is partialy funded by National Flagship Project, Taiwan (MOST 106-3114-Y404-002).
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Echovirus ,viruses ,Disease ,medicine.disease_cause ,0302 clinical medicine ,030212 general & internal medicine ,MESH: Hand, Foot and Mouth Disease ,Enterovirus ,biology ,MESH: Asia ,MESH: Enterovirus Infections ,3. Good health ,Infectious Diseases ,MESH: Enterovirus A, Human ,[SDV.MP.VIR]Life Sciences [q-bio]/Microbiology and Parasitology/Virology ,MESH: Sentinel Surveillance ,Molecular Medicine ,Asia ,030231 tropical medicine ,Taiwan ,Coxsackievirus ,Herpangina ,03 medical and health sciences ,MESH: Viral Vaccines ,Environmental health ,medicine ,Enterovirus Infections ,Humans ,MESH: Taiwan ,MESH: Pacific Ocean ,Disease burden ,Licensure ,MESH: Humans ,Pacific Ocean ,General Veterinary ,General Immunology and Microbiology ,business.industry ,Public Health, Environmental and Occupational Health ,Outbreak ,Viral Vaccines ,Congresses as Topic ,biology.organism_classification ,medicine.disease ,Enterovirus A, Human ,[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie ,business ,Hand, Foot and Mouth Disease ,Vaccine ,Sentinel Surveillance ,Asia-Pacific region ,MESH: Congresses as Topic - Abstract
International audience; Enteroviruses (EV), the major pathogens of hand, foot, and mouth disease (HFMD) and herpangina, affect millions of children each year. Most human enteroviruses cause self-limited infections except polioviruses, enterovirus A71 (EV-A71), enterovirus D68 (EV-D68), and several echoviruses (Echo) and coxsackieviruses (CV). Especially, EV-A71 has repeatedly caused large-scale outbreaks in the Asia-Pacific region since 1997. Some Asian countries have experienced cyclical outbreaks of severe EV-A71 infections and initiated development of EV-A71 vaccines. Five EV-A71 vaccine candidates have been clinically evaluated and three of them were approved for marketing in China. However, none of the China-approved products seek marketing approval in other countries. This situation supports a role for collaboration among Asian countries to facilitate clinical trials and licensure of EV-A71 vaccines. Additionally, enterovirus D68 outbreaks have been reported in the US and Taiwan currently and caused severe complications and deaths. Hence, an Asia-Pacific Network for Enterovirus Surveillance (APNES) has been established to estimate disease burden, understand virus evolution, and facilitate vaccine development through harmonizing laboratory diagnosis and data collection. Founded in 2017, the APNES is comprised of internationally recognized experts in the field of enterovirus in Asian countries working to raise awareness of this potentially fatal and debilitating disease. This article demonstrated the summaries of the first expert meeting, 2017 International Workshop on Enterovirus Surveillance and Vaccine Development, held by APNES in Taipei, Taiwan, March 2017.
- Published
- 2019
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