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Under the conditions of intensive milk production, impaired function of the mammary gland causing huge economic losses. The etiology of these disorders are primarily associated with microbial pathogens, although it should be emphasized the importance of deficit micro and macroelements. To preserve the health status of the mammary gland of cows, an important role played by a balanced diet with the proper ratio of micro and macroelements. The basis of this research is to investigate the relationship of blood and milk serum zinc concentrations in different stages of lactation and the effect on somatic cell count. The study included two groups of 15 cows. The first group of cows were control group. The second group is an experimental group and received daily 240 mg/kg supplements of zinc in food, from the dry period to six months of lactation. Zinc values were obtained by taking samples of blood and milk of cows twice a year (30 and 150 days of lactation). The observed oscillations are worth their concentrations at different stages of lactation as well as differences in somatic cells count. [ABSTRACT FROM AUTHOR]