1. Asinine herpesvirus‐3 (equine herpesvirus‐8)‐associated neurological disease in a donkey
- Author
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Linda van den Wollenberg, Ellen van der Zaag, Marianne M. Sloet van Oldruitenborgh-Oosterbaan, Rianne Buter, and Kees van Maanen
- Subjects
0301 basic medicine ,medicine.medical_specialty ,Ataxia ,General Veterinary ,040301 veterinary sciences ,business.industry ,04 agricultural and veterinary sciences ,Anus ,Hypotonia ,Virus ,0403 veterinary science ,03 medical and health sciences ,030104 developmental biology ,medicine.anatomical_structure ,Nasal Swab ,Internal medicine ,medicine ,Pituitary pars intermedia dysfunction ,Donkey ,medicine.symptom ,Equine herpesvirus ,business - Abstract
A 30-year-old female donkey with pituitary pars intermedia dysfunction (PPID) was referred to the Department of Equine Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, for losing weight despite good appetite and treatment for PPID. Twelve days after returning home, the mare developed nasal discharge, and the next day it was found recumbent and was only able to stand up with manual assistance. The next day the mare showed severe tetraparesis, ataxia, and hypotonia of anus, tail and bladder, and it became completely recumbent. Equine herpesvirus myeloencephalopathy was suspected, and to confirm the diagnosis a deep nasal swab was taken. Because of the poor prognosis the mare was euthanased. The swab scored very strong positive for equine herpesvirus-1 (EHV-1) and virus isolation was performed to enable further characterisation of the virus. The identity of the virus was again confirmed as EHV-1 with type-specific monoclonal antibodies, but sequencing identified the virus as asinine herpesvirus-3 (EHV-8).
- Published
- 2017