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8 results on '"Zamò, Alberto"'

1. The many faces of nodal and splenic marginal zone lymphomas. A report of the 2022 EA4HP/SH lymphoma workshop

Author

Zamò, Alberto, primary, van den Brand, Michiel, additional, Climent, Fina, additional, de Leval, Laurence, additional, Dirnhofer, Stefan, additional, Leoncini, Lorenzo, additional, Ng, Siok-Bian, additional, Ondrejka, Sarah L., additional, Quintanilla-Martinez, Leticia, additional, Soma, Lorinda, additional, and Wotherspoon, Andrew, additional

Published
2023
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2. Correction to: The many faces of nodal and splenic marginal zone lymphomas. A report of the 2022 EA4HP/SH lymphoma workshop

Author

Zamò, Alberto, primary, van den Brand, Michiel, additional, Climent, Fina, additional, de Leval, Laurence, additional, Dirnhofer, Stefan, additional, Leoncini, Lorenzo, additional, Ng, Siok‑Bian, additional, Ondrejka, Sarah L., additional, Quintanilla‑Martinez, Leticia, additional, Soma, Lorinda, additional, and Wotherspoon, Andrew, additional

Published
2023
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3. Correction to: Cavity-based lymphomas: challenges and novel concepts. A report of the 2022 EA4HP/SH lymphoma workshop

Author

Di Napoli, Arianna, primary, Soma, Lori, additional, Quintanilla‑Martinez, Leticia, additional, de Leval, Laurence, additional, Leoncini, Lorenzo, additional, Zamò, Alberto, additional, Ng, Siok‑Bian, additional, Ondrejka, Sarah L., additional, Climent, Fina, additional, Wotherspoon, Andrew, additional, and Dirnhofer, Stefan, additional

Published
2023
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4. Cavity-based lymphomas: challenges and novel concepts

Author

Di Napoli, Arianna, primary, Soma, Lori, additional, Quintanilla-Martinez, Leticia, additional, de Leval, Laurence, additional, Leoncini, Lorenzo, additional, Zamò, Alberto, additional, Ng, Siok-Bian, additional, Ondrejka, Sarah L., additional, Climent, Fina, additional, Wotherspoon, Andrew, additional, and Dirnhofer, Stefan, additional

Published
2023
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8. Constitutive expression of ΔN-p63α isoform in human thymus and thymic epithelial tumours

Author

Chilosi, Marco, Zamò, Alberto, Brighenti, Antonietta, Malpeli, Giorgio, Montagna, Licia, Piccoli, Paola, Pedron, Serena, Lestani, Maurizio, Inghirami, Giorgio, Scarpa, Aldo, Doglioni, Claudio, and Menestrina, Fabio

Abstract

p63, a member of the p53 family, is involved in the survival and differentiation of reserve/stem cells in different epithelia. To unveil the possible role of p63 in thymic physiology and pathology, we investigated the expression of p63 isoforms in normal thymus, thymomas and other mediastinal tumours. All samples were analysed using immunohistochemistry with three different antibodies: 4A4 antibody recognising all p63 isoforms, p40 antibody reacting only with truncated dominant-negative isoforms (?N-p63) and H-129 antibody recognising all alpha-isoforms. Reverse-transcription polymerase chain reaction (RT-PCR), and real-time PCR analyses were performed on RNA extracted from frozen samples of four thymomas and two primary-mediastinal large-B-cell lymphoma (PMLBCL). In normal thymus, ?N-p63a was expressed in all cortical and medullary epithelial cells, with decreasing intensity in Hassall's corpuscles. This phenotype was conserved in neoplastic transformation since all 54 investigated thymomas (World Health Organization types A, AB, B1, B2, B3, C) expressed ?N-p63a (virtually 100% cells). The predominance of ?N-p63a isoform mRNA was confirmed by real-time PCR. Among other mediastinal tumours, ?N-p63a was only expressed in those displaying either a stratified epithelial component (teratomas) or epidermoid differentiation (lung carcinoma). Among lymphomas, T-cell-precursor lymphomas did not express p63, whereas most PMLBCL expressed TA-p63a (7/8).

Published
2003
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