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Background/Aim. Popliteal artery aneurysm (PAA) is the most common peripheral artery aneurysm and second most common aneurysm following abdominal aortic aneurysm (AAA). Still, its incidence is rare and treatment non-standardized. Collection of data in multicenter registry could improve diagnosis and treatment. SerbVasc is newly established data collection collaboration among Serbian Vascular centers. The aim of this study was to assess common surgical practice in diagnosis and treatment of patients with PAA in Serbian hospitals. Methods. Serbian vascular centers that accepted invitation collected retrospectively data about operated patients for PAA in the period 2012-2018. Data regarding symptoms, preoperative diagnostics, vascular and endovascular techniques and postoperative results were collected. This data set was submitted to the VASCUNET international project of PAA for data analysis between the countries. The same data set was used for detailed analysis of contemporary treatment of PAA in six Serbian hospitals: Serbian Clinical Centre (SCC), Dedinje Cardiovascular Institute (CVID), Military Medical Academy (MMA), Clinical Center Novi Sad (CCNS), Clinical Centre Nis (CCN) and County Hospital Uzice (CHU). Results. In the period 2012-2018 in six Serbian hospitals data for 342 procedures due to PAA were collected in 329 (96.2%) men and only 13 (3.8%) women. Incidence of PAA repair was 6.8 operations/million inhabitants /year. Mean age of patients was 64.34 years (ranging from 29 to 87). Total of 223 (65.8%) elective procedures were performed. Amputation and hospital survival were considered as the main outcomes. Thrombosis was recorded in 110 (32.4%) of patients, as a cause for surgery and rupture in 5 patients. Mean diameter of aneurysm was 35.28 mm being larger for ruptured aneurysms (43.8 mm) in average. Both synthetic and vein grafts were used in elective and urgent procedures equally. Endovascular procedures were performed in 6 (1.8 %) cases. Conclusion. This study confirms importance of registry-based collection of data and their analysis. It showed that national incidence of PAA in Serbia is low and that well organized, even per institution based, screening algorithm should improve recognition of such patients and increase number of electively treated PAA. Education of vascular surgeons to use posterior approach could improve vascular healthcare.