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Your search keyword '"Wodniecki, J."' showing total 18 results
Start Over Author "Wodniecki, J." Journal wiadomosci lekarskie warsaw poland 1960
18 results on '"Wodniecki, J."'

1. [Effect of hyperglycemia on glutathione peroxidase and superoxide dismutase activity in patients with newly diagnosed carbohydrate metabolism disturbances].

Author

Kasperczyk S, Przywara B, Kasperczyk A, Birkner E, Wodniecki J, Ostałowska A, and Krauze-Wielicka M

Subjects
Diabetes Complications, Erythrocytes enzymology, Glucose Tolerance Test, Humans, Hyperglycemia etiology, Diabetes Mellitus enzymology, Glutathione Peroxidase blood, Hyperglycemia enzymology, Superoxide Dismutase blood
Abstract

The aim of our study was to estimate the changes of superoxide dismutase (both isoenzymes: SOD-Zn, Cu and SOD-Mn in serum and total activity in erythrocytes) and gluthatione peroxidase (in erythrocytes) activities in newly diagnosed carbohydrate metabolism disturbances. 80 subjects were divided into two groups: the control with normal oral tolerance glucose test (OGTT) (n = 44) and investigated group (concentration of fasting glucose over 6.1 mmol/l and/or concentration of glucose in second hour of OGTT over 7.8 mmol/l) (n = 36). No differences of superoxide dismutase and gluthatione peroxidase activities as well as negative correlation between gluthatione peroxidase activity and concentration of glucose in second hour of OGTT (R = -0.28; p = 0.032) were observed. Falling tendency of gluthatione peroxidase activity in erythrocytes in subjects with postprandial hyperglycaemia suggest that this enzyme could be an early marker of antioxidant status of carbohydrate metabolism disturbances.

Published
2002

2. [Genetic changes and clinical management in familial hypertrophic cardiomyopathy].

Author

Domal-Kwiatkowska D, Smolik S, Mazurek U, Moric E, Polońska J, Nowalany-Kozielska E, Glanowska G, Wodniecki J, Szarek J, Wilczewski P, Kozakiewicz K, Tendera M, and Wilczok T

Subjects
Gene Expression genetics, Humans, Microfilament Proteins genetics, Myosin Heavy Chains genetics, Point Mutation genetics, Prognosis, Troponin I genetics, Troponin T genetics, Cardiomyopathy, Hypertrophic diagnosis, Cardiomyopathy, Hypertrophic genetics
Abstract

Hypertrophic cardiomyopathy (HCM) is phenotypically and genotypically heterogeneous disease of heart. Nine chromosomal loci responsible for this condition have been identified: beta-myosin heavy chain, essential and regulatory myosin light chains, troponin T and I subunits, alpha-tropomosin, cardiac myosin binding protein C, cardiac actin and titin. These genes code for proteins involved in the contraction mechanism or in the control of contraction, therefore HCM has been classified as a disease of cardiac sarcomere. Over 107 mutations have been identified. More then half of them have been detected in the beta-myosin heavy chain gene (beta-MHC). Some mutations in beta-MHC gene are associated with a benign prognosis, other are associated with high incidence of sudden cardiac death (SCD) and severe hypertrophy. Mutations in myosin binding protein C are associated with mild, delayed expression of cardiac hypertrophy and benign prognosis. Mutations in cardiac troponinT are associated with a mild degree of hypertrophy but a high incidence of SCD. Study of genes responsible for HCM will assume role in the context of clinical management of HCM, in particular regarding diagnosis and prognosis patients and families with HCM.

Published
2000

3. [Coenzyme Q--clinical significance].

Author

Jacheć W, Wodniecki J, and Kamiński K

Subjects
Cardiovascular Diseases physiopathology, Diabetes Mellitus physiopathology, Endocrine System Diseases physiopathology, Humans, Musculoskeletal Diseases physiopathology, Obesity physiopathology, Ubiquinone physiology
Abstract

In the paper the clinical importance is presented of the use of coenzyme Q (ubiquinone) preparation. On the basis of available literature the participation of coenzyme Q was determined in the pathogenesis and aetiology of a number of diseases, e.g. diseases of the circulatory system, locomotor system, diabetes mellitus, obesity or endocrine system diseases.

Published
1994

4. [Analysis of usefulness for quantitative methods determining segmental mobility in assessing contrast ventriculography of the left ventricle].

Author

Bartoszewski A, Walichiewicz P, Tendera M, Wodniecki J, Poloński L, Szczurek K, and Wilczek K

Subjects
Evaluation Studies as Topic, Humans, Myocardial Contraction physiology, Stroke Volume, Ventricular Function, Left, Gated Blood-Pool Imaging methods, Ventricular Dysfunction, Left diagnostic imaging
Abstract

The aim of this study was to compare two different quantitative methods used to determine left ventricular regional wall motions. Circumferential and radial methods were used to distinguish between normo- and hypokinesia of the 5 segments proposed by AHA for RAO position. One hundred ventriculograms were analyzed. Fifty cases with normal wall motion and ejection fraction greater than 55% were chosen as a base to enumerate normokinetic values of regional contractility. The other fifty cases represented hypokinesia of different segments. Respective values for the radial method were 61.42 vs 38.10 for antero-basal segment, 73.8 vs 58.5 for antero-lateral segment, 67.74 vs 42.5 for apical segment, 69.88 vs 47.70 for postero-lateral segment and 41.72 vs 33.4 for postero-lateral segment. The values obtained with the circumferential method were 12.27 vs 10.21, 20.06 vs 16.21, 22.19 vs 18.78, 17.08 vs 11.39 and 8.50 vs 8.15, respectively. These results suggest that the radical method allows to better differentiate between hypo- and normokinesia. Postero-basal segment proved to be most difficult to assess. Both methods fail to make a clear distinction in these cases.

Published
1993

8. [3 cases of neoplasm metastasis to the heart].

Author

Wodniecki J, Kowalski S, Prochaczek F, Zalewski J, and Urgacz-Ficek J

Subjects
Adult, Autopsy, Female, Humans, Male, Middle Aged, Neoplasm Metastasis, Carcinoma pathology, Gallbladder Neoplasms pathology, Heart Neoplasms pathology, Laryngeal Neoplasms pathology
Published
1975

15. [Clinical analysis of 20 cases of multiple myeloma].

Author

Machalski M, Wodniecki J, and Jankowska B

Subjects
Adult, Aged, Blood Proteins, Bone Marrow Examination, Female, Humans, Male, Middle Aged, Multiple Myeloma drug therapy, Cyclophosphamide therapeutic use, Multiple Myeloma diagnosis
Published
1967

16. [Clinical evaluation of Provasan].

Author

Wodniecki J and Wolański A

Subjects
Adult, Aged, Arteriosclerosis drug therapy, Cholesterol metabolism, Humans, Lipid Metabolism, Male, Middle Aged, Oxygen Consumption, Thromboangiitis Obliterans drug therapy, Time Factors, Hypercholesterolemia drug therapy, Nicotinic Acids therapeutic use, Vascular Diseases drug therapy
Published
1970

17. [Case of primary pulmonary hemosiderosis].

Author

Wodniecki J and Singer Z

Subjects
Adult, Electrocardiography, Humans, Male, Prednisone therapeutic use, Hemosiderosis diagnosis, Hemosiderosis drug therapy, Lung Diseases diagnosis
Published
1971

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