Search

2019 DEC 24 (NewsRx) -- By a News Reporter-Staff News Editor at World Disease Weekly -- Investigators publish new report on Membrane Proteins - Peptide Receptors. According to news reporting [...]

2017 APR 11 (NewsRx) -- By a News Reporter-Staff News Editor at World Disease Weekly -- From Alexandria, Virginia, NewsRx journalists report that a patent by the inventor Daniell, Henry [...]

By a News Reporter-Staff News Editor at World Disease Weekly -- New research on Immunization is the subject of a report. According to news reporting out of Coimbatore, India, by [...]

According to a study from Japan, nuclear transfer (NT) reprogramming does not improve the low developmental potency of embryonic stem (ES) cells induced by long-term culture. "Epigenetic states of ES [...]

Investigators in the United States, Germany and United Kingdom have published new genetics data. Study 1: According to recent research from the United States, translation repression by microRNA (miRNA)-induced gene [...]

Genetics research advances have been reported from Germany, the United States and the People's Republic of China. Study 1: According to recent research from Germany, genome-wide profiling of CpG methylation [...]

Gastrointestinal tract secretions reduce the stability of recombinant adeno-associated virus type 2 vectors after peroral administration. According to a study from the United States, "The transfer of exogenous genetic material [...]

According to a study from the United States, epigenomic profiling reveals novel and frequent targets of aberrant DNA methylation-mediated silencing in malignant glioma. "Malignant glioma is the most common central [...]

For the first time, scientists have engineered yeast cells capable of producing a broad repertoire of recombinant therapeutic proteins with fully human sugar structures (glycosylation). These sugar structures ensure a [...]

Transgenic mice expressing human MPO-463G/A alleles is a model for atherosclerotic and hyperlipidemia. "Myeloperoxidase (MPO) is an oxidant-generating enzyme present in macrophages at atherosclerotic lesions and implicated in coronary artery [...]

Data on transplants are outlined in reports from the United States, Turkey and Netherlands. Study 1: The radiological treatment of biliary strictures with balloon dilation and stenting can be performed [...]

The multistep pathogenesis of colorectal cancer involves the accumulation of CpG island methylation of genes. According to a study from the United States, "Genetic alterations occur during the adenoma-carcinoma sequence [...]

Stearylated octaarginine and artificial virus-like particles show promise as agents for transfection of siRNA into primary rat neurons. According to a study from Germany, "RNA interference (RNAi) provides a powerful [...]

Spontaneous recovery from hyperglycemia by regeneration of pancreatic beta-cells is observed in Kir6.2G132S transgenic mice. According to a study from Japan, "The ATP-sensitive K[superscript]+ channel (K[subscript]ATP channel) in pancreatic beta-cells [...]

Transgenic insulin (B:9-23) T-cell receptor mice develop autoimmune diabetes dependent upon RAG genotype, H-2[superscript]g7 homozygosity, and insulin 2 gene knockout. According to a study from the United States, "A series [...]

A 3-dimensional tissue engineered scaffold plus a nonviral gene carrier enhances mesenchymal stem cell DNA expression. "The objective of this study is to enhance the expression of a plasmid DNA [...]

According to a study from the United States, germline transmission is facilitated in genetically modified primordial germ cells (PGCs). "PGCs are the precursors of sperm and eggs. In most animals, [...]

Data on HIV/AIDS are outlined in reports from the United States and Japan. Study 1: DNA prime/protein boost immunization against HIV clade C was safe and immunogenic in mice. According [...]

Transgenic mice express recombinant human antihantavirus monoclonal antibodies. According to a study from the People's Republic of China, "Transgenic mice expressing a recombinant human monoclonal antibody (rHMAb) against hantavirus were [...]

According to a study from the United States, cervical cancer HPV16 oncogene silencing is affected by RNA interference. "RNA interference-mediated gene silencing has the potential to block gene expression. A [...]

According to a study from Japan, Bloom syndrome gene expression is silenced in human cells by gene targeting. "Gene targeting via homologous recombination is a powerful tool for studying gene [...]

Estimates are that only about 10% of the roughly 25,000 genes in the human genome are activated, or & quot;on, & quot; at any given time in a particular cell [...]

DNA research advances have been reported from Japan, Belgium and Ireland. Study 1: According to a study from Japan, a DNA vaccine using hemagglutinating virus of Japan-liposome encapsulating combination encoding [...]

According to a study from Japan, cancer vaccine therapy improved using genetically modified dendritic cells (DCs) expressing tumor-associated antigen. & quot;The T-helper 1 (Th1) immune reaction is most important in [...]

Investigators in the People's Republic of China, United Kingdom and Japan have published new oncology data. Study 1: Breast cancer becomes more aggressive with tissue inhibitor of metalloproteinase-3 (TIMP3) gene [...]

Genetic manipulation of two fowlpox virus late transcriptional regulatory elements influences their ability to direct expression of foreign genes. According to a study from the United States, "Fowlpox virus (FWPV) [...]

According to a study from Germany, stable gene silencing of cyclin B1 in tumor cells increases susceptibility to taxol and leads to growth arrest in vivo. "Cyclin B1 is the [...]

According to a study from France, in vitro oocyte maturation requires study of epigenetic safety. "Imprinting is an epigenetic modification that is reprogrammed in the germ line and leads to [...]

An oral tuberculosis vaccine produced from a transgenic plant is immunogenic. "Transgenic plants are a novel way to produce and deliver oral vaccines. Arabidopsis thaliana material shown previously to express [...]

Investigators have identified the CD4-dependent potentiation of a high molecular weight-melanoma-associated antigen-specific CTL response in HLA-A2/K[superscript]b transgenic mice. "The human high molecular weight (m.w.)-melanoma-associated antigen (HMW-MAA) is ail attractive target [...]

Data on oncology are outlined in reports from the People's Republic of China, United States and Japan. Study 1: Breast cancer becomes more aggressive with tissue inhibitor of metalloproteinase-3 (TIMP3) [...]

According to a study from Spain, adenovirus virus-associated RNA is processed to functional interfering RNAs involved in virus production. "Posttranscriptional gene silencing allows sequence-specific control of gene expression. Specificity is [...]

Investigators in Canada, Japan and the United States have published new apoptosis data. Study 1: Data provide evidence that nuclear factor-kappaB (NF-kappaB) suppresses mitochondrial defects and cell death of ventricular [...]

According to a study from the United States, sickle cell anemia can be treated by coregulating globin transgene expression and RNA interference (RNAi). "The application of RNA interference (RNAi) to [...]

Research and Markets has announced the addition of "Emerging Technologies: Stem Cells, Genes and Monoclonal Antibodies" to its product line. Three technologies promise to shape the future of drug discovery [...]

Scientists review methods for engineering chromosomes to deliver therapeutic genes in a recent issue of Trends in Biotechnology. According to the review from Australia, "The "The ability to create fully [...]

Researchers have identified a new and unusual tumor suppressor gene that may be important in cancers of the lung and head and neck. The study shows that restoring the inactivated [...]

According to a study from Japan, aberrant methylation of the CHFR gene occurs in advanced hepatocellular carcinoma (HCC). "Recently, aberrant methylation of the CHFR gene associated with gene silencing has [...]

Investigators in Japan and the United States have published new Prostate Cancer data. Study 1: Pin1-targeted RNA interference stops angiogenesis and growth in prostate tumors. "The peptidyl-prolyl isomerase Pin1 plays [...]

According to a study from England, SIRT1 is a target for killling epithelial cancer cells. "SIRT1 is a conserved NAD-dependent deacetylase that regulates life span in accord with nutritional provision. [...]

New findings from Australia, Germany and the United States describe advances in oncology. Study 1: Early growth response gene 1 (EGR1) is a key regulator of heparanase in tumor cells. [...]

According to a report from Ireland, changes in alternative splicing of human and mouse genes are accompanied by faster evolution of constitutive exons. "Alternative splicing is known to be an [...]

Data on hematology are outlined in reports from Germany, France and the United Kingdom. Study 1: HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. According to a study [...]

According to a study from France, interactions between the rabbit CSN1 gene and the nuclear matrix of stably transfected HC11 mammary epithelial cells vary with its level of expression. "The [...]

New findings from Japan, Israel and Canada describe advances in oncology. Study 1: The Brm gene is suppressed at the post-transcriptional level in various human cell lines and is inducible [...]

HOXB4 enforces equivalent fates of ES-cell-derived and adult hematopoietic cells. According to a study from Austria and Germany, "Genetic manipulation of hematopoietic stem and progenitor cells is an important tool [...]

Parkinson disease research advances have been reported from Sweden and Japan. Study 1: Continued delivery of glial cell line-derived neurotrophic factor (GDNF) may optimize neural transplantation therapy, report researchers at [...]

Scientists describe functional interactions of anti-apoptotic proteins and tumor necrosis factor in the context of a replication-competent adenovirus in a recent issue of Gene Therapy. According to a study from [...]

Investigators in the United States have published new gene silencing data. Study 1: RNA interference elicits tumor response despite hypoxia-induced VEGF-A. "Vascular endothelial cell growth factor A (VEGF-A) and hypoxia [...]

Data on liver cancer are outlined in reports from Singapore, France and the United States. Study 1: The hepaCAM gene is silenced in human hepatocellular carcinoma. "Previously, we reported on [...]