8 results on '"Eric J, Ley"'
Search Results
2. A Systems-based Approach to Reduce Deep Venous Thrombosis and Pulmonary Embolism in Trauma Patients
- Author
-
Ting Lung Lin, Russell Mason, Navpreet K. Dhillon, Galinos Barmparas, Daniel R. Margulies, Bruce L. Gewertz, Audrey R. Yang, Eric J. Ley, Harveen K Sekhon, and Nikhil T Linaval
- Subjects
medicine.medical_specialty ,business.industry ,Trauma center ,Vascular surgery ,medicine.disease ,Pulmonary embolism ,Cardiac surgery ,03 medical and health sciences ,Venous thrombosis ,0302 clinical medicine ,Blunt trauma ,030220 oncology & carcinogenesis ,Anesthesia ,medicine ,030211 gastroenterology & hepatology ,Surgery ,Dosing ,business ,Abdominal surgery - Abstract
Venous thromboembolism (VTE) in trauma patients carries significant morbidity and mortality. We previously described how titrating enoxaparin dosing by anti-Xa trough levels was associated with a lower VTE rate. We combined this strategy with a higher initial enoxaparin dose for a majority of patients and modified the electronic medical record (EMR) to encourage immediate dosing. We sought to determine if this systems-based approach was associated with a decrease in VTE rate. A retrospective review was conducted of all trauma patients on prophylactic enoxaparin at an academic, Level I Trauma Center from 01/2013 to 05/2014 (PRE) and 06/2015 to 02/2018 (POST). The patients in PRE were prescribed enoxaparin 30 mg twice daily without dose adjustments. The patients in POST received 40 mg twice daily unless exclusion criteria applied, with doses titrated to maintain anti-Xa trough levels between 0.1 and 0.2 IU/mL. There were 478 patients in the PRE and 1306 in the POST. Compared to PRE, POST patients were of similar age and were as likely to present after blunt trauma, although POST patients had lower injury severity scores (10 vs. 9, p
- Published
- 2020
- Full Text
- View/download PDF
3. The Application of Human Factors Engineering to Reduce Operating Room Turnover in Robotic Surgery
- Author
-
Tara N, Cohen, Jennifer T, Anger, Kevin, Shamash, Kenneth R, Catchpole, Raymund, Avenido, Eric J, Ley, Bruce L, Gewertz, and Daniel, Shouhed
- Subjects
Operating Rooms ,Time Factors ,Robotic Surgical Procedures ,Humans ,Personnel Turnover ,Ergonomics - Abstract
Challenges associated with turnover time are magnified in robotic surgery. The introduction of advanced technology increases the complexity of an already intricate perioperative environment. We applied a human factors approach to develop systematic, data-driven interventions to reduce robotic surgery turnover time.Researchers observed 40 robotic surgery turnovers at a tertiary hospital [20 pre-intervention (Jan 2018 to Apr 2018), 20 post-intervention (Jan 2019 to Jun 2019)]. Components of turnover time, including cleaning, instrument and room set-up, robot preparation, flow disruptions, and major delays, were documented and analyzed. Surveys and focus groups were used to investigate staff perceptions of robotic surgery turnover time. A multidisciplinary team of human factors experts and physicians developed targeted interventions. Pre- and post-intervention turnovers were compared.Median turnover time was 67 min (mean: 72, SD: 24) and 22 major delays were noted (1.1/case). The largest contributors were instrument setup (25.5 min) and cleaning (25 min). Interventions included an electronic dashboard for turnover time reporting, clear designation of roles and simultaneous completion of tasks, process standardization of operating room cleaning, and data transparency through monthly reporting. Post-intervention turnovers were significantly shorter (U = 57.5, p = .000) and ten major delays were noted.Human factors analysis generated interventions to improve turnover time. Significant improvements were seen post-intervention with a reduction in turnover time by a 26 min and decrease in major delays by over 50%. Future opportunities to intervene and further improve turnover time include targeting pre- and post-operative care phases.
- Published
- 2022
4. A Systems-based Approach to Reduce Deep Venous Thrombosis and Pulmonary Embolism in Trauma Patients
- Author
-
Navpreet K, Dhillon, Galinos, Barmparas, Ting Lung, Lin, Nikhil T, Linaval, Audrey R, Yang, Harveen K, Sekhon, Russell, Mason, Daniel R, Margulies, Bruce L, Gewertz, and Eric J, Ley
- Subjects
Venous Thrombosis ,Anticoagulants ,Humans ,Prospective Studies ,Venous Thromboembolism ,Pulmonary Embolism ,Retrospective Studies - Abstract
Venous thromboembolism (VTE) in trauma patients carries significant morbidity and mortality. We previously described how titrating enoxaparin dosing by anti-Xa trough levels was associated with a lower VTE rate. We combined this strategy with a higher initial enoxaparin dose for a majority of patients and modified the electronic medical record (EMR) to encourage immediate dosing. We sought to determine if this systems-based approach was associated with a decrease in VTE rate.A retrospective review was conducted of all trauma patients on prophylactic enoxaparin at an academic, Level I Trauma Center from 01/2013 to 05/2014 (PRE) and 06/2015 to 02/2018 (POST). The patients in PRE were prescribed enoxaparin 30 mg twice daily without dose adjustments. The patients in POST received 40 mg twice daily unless exclusion criteria applied, with doses titrated to maintain anti-Xa trough levels between 0.1 and 0.2 IU/mL.There were 478 patients in the PRE and 1306 in the POST. Compared to PRE, POST patients were of similar age and were as likely to present after blunt trauma, although POST patients had lower injury severity scores (10 vs. 9, p 0.01). The overall VTE rate was lower in POST (6.9% vs. 3.6%, p 0.01). The adjusted risk of VTE (AOR 0.61, adjusted p = 0.04) was lower in POST and POST was independently protective for VTE (AOR 0.54; p = 0.01).By implementing system changes to improve enoxaparin dosing after trauma, a significant reduction in VTE rate was observed. Wider application of this strategy should be considered.
- Published
- 2020
5. Does Beta-Blockade Reduce the Risk of Depression in Patients with Isolated Severe Extracranial Injuries?
- Author
-
Olle Ljungqvist, Eric J. Ley, Shahin Mohseni, Rebecka Ahl, Galinos Barmparas, Göran Wallin, and Louis Riddez
- Subjects
Adult ,Male ,Risk ,medicine.medical_specialty ,Original Scientific Report ,Adrenergic beta-Antagonists ,Stress Disorders, Post-Traumatic ,03 medical and health sciences ,Injury Severity Score ,0302 clinical medicine ,medicine ,Humans ,Depression (differential diagnoses) ,Aged ,Retrospective Studies ,Depression ,business.industry ,Retrospective cohort study ,Middle Aged ,Vascular surgery ,030227 psychiatry ,Surgery ,Blockade ,Cardiac surgery ,Cardiothoracic surgery ,Anesthesia ,Female ,business ,030217 neurology & neurosurgery ,Abdominal surgery - Abstract
Background Approximately half of trauma patients develop post-traumatic depression. It is suggested that beta-blockade impairs trauma memory recollection, reducing depressive symptoms. This study investigates the effect of early beta-blockade on depression following severe traumatic injuries in patients without significant brain injury. Methods Patients were identified by retrospectively reviewing the trauma registry at an urban university hospital between 2007 and 2011. Severe extracranial injuries were defined as extracranial injuries with Abbreviated Injury Scale score ≥3, intracranial Abbreviated Injury Scale score
- Published
- 2017
- Full Text
- View/download PDF
6. Nonoperative Management of Blunt Splenic Trauma in Patients with Traumatic Brain Injury: Feasibility and Outcomes
- Author
-
Kavita A. Patel, Nikhil T Linaval, Navpreet K. Dhillon, Daniel R. Margulies, Emma Gillette, Gretchen M. Thomsen, Galinos Barmparas, and Eric J. Ley
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,Traumatic brain injury ,Wounds, Nonpenetrating ,Blunt splenic trauma ,03 medical and health sciences ,Young Adult ,0302 clinical medicine ,Blunt ,Injury Severity Score ,Brain Injuries, Traumatic ,medicine ,Humans ,Treatment Failure ,Aged ,Retrospective Studies ,business.industry ,Head injury ,030208 emergency & critical care medicine ,Retrospective cohort study ,Vascular surgery ,Middle Aged ,medicine.disease ,Hospitalization ,Logistic Models ,Anesthesia ,Surgery ,Female ,business ,030217 neurology & neurosurgery ,Spleen ,Abdominal surgery - Abstract
Preventing secondary insult to the brain is imperative following traumatic brain injury (TBI). Although TBI does not preclude nonoperative management (NOM) of splenic injuries, development of hypotension in this setting may be detrimental and could therefore lead trauma surgeons to a lower threshold for operative intervention and a potentially higher risk of failure of NOM (FNOM). We hypothesized that the presence of a TBI in patients with blunt splenic injury would lead to a higher risk of FNOM. Patients with blunt splenic injury were selected from the National Trauma Data Bank research datasets from 2007 to 2011. TBI was defined as AIS head ≥ 3 and FNOM as patients who underwent a spleen-related operation after 2 h from admission. TBI patients were compared to those without head injury. The primary outcome was FNOM. Of 47,713 patients identified, 41,436 (86.8%) underwent a trial of NOM. FNOM was identical (10.6 vs. 10.8%, p = 0.601) among patients with and without TBI. TBI patients had lower adjusted odds for FNOM (AOR 0.66, p
- Published
- 2018
7. Flow disruptions during trauma care
- Author
-
Daniel R. Margulies, Eric J. Ley, Douglas A. Wiegmann, Richard Karl, Alex Gangi, Jennifer Blaha, Ben Starnes, Daniel Shouhed, Cathy Karl, Ken Catchpole, Bruce L. Gewertz, and Renaldo C. Blocker
- Subjects
medicine.medical_specialty ,Operating Rooms ,Process assessment ,business.industry ,Flow disruption ,Communication ,Trauma center ,Process Assessment, Health Care ,Emergency department ,medicine.disease ,Trauma care ,Trauma Centers ,Health care ,medicine ,Trauma team ,Humans ,Wounds and Injuries ,Surgery ,Medical emergency ,Prospective Studies ,Intensive care medicine ,business ,Background flow - Abstract
Flow disruptions (FDs) are deviations from the progression of care that compromise safety or efficiency. The frequency and specific causes of FDs remain poorly documented in trauma care. We undertook this study to identify and quantify the rate of FDs during various phases of trauma care.Seven trained observers studied a Level I trauma center over 2 months. Observers recorded details on FDs using a validated Tablet-PC data collection tool during various phases of care-trauma bay, imaging, operating room (OR)-and recorded work-system variables including breakdowns in communication and coordination, environmental distractions, equipment issues, and patient factors.Researchers observed 86 trauma cases including 72 low-level and 14 high-level activations. Altogether, 1,759 FDs were recorded (20.4/case). High-level trauma comprised a significantly higher number (p = 0.0003) and rate of FDs (p = 0.0158) than low-level trauma. Across the three phases of trauma care, there was a significant effect on FD number (p0.0001) and FD rate (p = 0.0005), with the highest in the OR, followed by computed tomography. The highest rates of FD per case and per hour were related to breakdowns in coordination.This study is the largest direct observational study of the trauma process conducted to date. Complexities associated with the critical patient who arrives in the trauma bay lead to a high prevalence of disruptions related to breakdowns in coordination, communication, equipment issues, and environmental factors. Prospective observation allows individual hospitals to identify and analyze these systemic deficiencies. Appropriate interventions can then be evaluated to streamline the care provided to trauma patients.
- Published
- 2013
8. Indications for routine pathologic examination of specimens removed during trauma operations
- Author
-
Dennis Anderson, Pedro G.R. Teixeira, Daniel R. Margulies, Eric J. Ley, Ryan Gertz, Ali Salim, Kenji Inaba, and Para Chandrasoma
- Subjects
Adult ,Male ,medicine.medical_specialty ,Adolescent ,medicine.medical_treatment ,Malignancy ,Gross examination ,Injury Severity Score ,Laparotomy ,Pathology Result ,Neoplasms ,medicine ,Humans ,Abnormal Finding ,Registries ,Child ,Aged ,Retrospective Studies ,Aged, 80 and over ,Pathology, Clinical ,business.industry ,Infant ,Retrospective cohort study ,Vascular surgery ,Length of Stay ,Middle Aged ,medicine.disease ,Los Angeles ,Surgery ,Thoracotomy ,Child, Preschool ,Wounds and Injuries ,Female ,Radiology ,business - Abstract
Surgical specimens removed during trauma operations are routinely submitted for examination by pathology. This practice has not been systematically evaluated and the incidence of abnormal results from these examinations remains unknown. The objective of this study was to identify the incidence and management implications of abnormal findings at pathology review of trauma specimens. This is a retrospective chart and pathology review of all surgical specimens obtained during laparotomy or thoracotomy for trauma between January 1, 1993 and December 31, 2005. Reports were assessed for significant abnormal findings, including malignancy, infectious processes, and chronic inflammation. Additional clinical and demographic data were obtained. The main outcome measure was any change in management due to the pathology result. A total of 1686 specimens were obtained from 1307 trauma patients. Ten patients (0.8%) were identified as having clinically significant abnormal findings on pathology. Six findings (0.5%) were evidence of malignancy. The pathology reports did not alter care in any patients. In all instances malignancy was known or highly suspected prior to specimen examination based on other diagnostic modalities or gross examination during surgery. Patients with an abnormal finding were significantly older than the patients with normal pathology reports (70.5 vs. 30.4, P
- Published
- 2010
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.