12 results on '"Ming Chen"'
Search Results
2. Bursectomy for advanced gastric cancer: an update meta-analysis
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Yuan Fang Li, Guo Ming Chen, Zhiwei Zhou, Run Cong Nie, Shu Mei Yan, Xiao Jiang Chen, Yingbo Chen, Shu Qiang Yuan, Shi Chen, and Yong Ming Chen
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medicine.medical_specialty ,Survival ,medicine.medical_treatment ,lcsh:Surgery ,Review ,lcsh:RC254-282 ,Standard procedure ,03 medical and health sciences ,0302 clinical medicine ,Postoperative Complications ,Surgical oncology ,Gastrectomy ,Stomach Neoplasms ,medicine ,Humans ,business.industry ,Bursectomy ,Significant difference ,Postoperative complication ,lcsh:RD1-811 ,Advanced gastric cancer ,Length of Stay ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Prognosis ,Surgery ,Meta-analysis ,Oncology ,030220 oncology & carcinogenesis ,Relative risk ,030211 gastroenterology & hepatology ,business ,Gastric cancer - Abstract
Background The present meta-analysis was to explore the surgical and oncological outcomes of bursectomy for advanced gastric cancer (AGC). Methods Relevant studies that evaluated the role of bursectomy for AGC were comprehensively examined to perform a meta-analysis. The primary outcomes were overall survival (OS) and disease-free survival (DFS). The secondary outcomes were the number of harvested lymph nodes (LNs), operation time, operative bleeding, hospital stay, postoperative complication and mortality. Results A total of seven studies comprising 2633 cases (1176 cases in the bursectomy group and 1457 cases in the non-bursectomy group) were finally included. There was no significant difference in OS (HR 0.95, P = 0.647) and DFS (HR 0.99, P = 0.936) between the two groups. Even for patients with serosa-penetrating tumours, OS was comparable between the two groups (HR 0.87, P = 0.356). The operation time of the bursectomy group was longer (weighted mean difference, WMD 32.76 min, P = 0.002). No significant difference was found between the two groups in terms of the number of dissected LNs (WMD 5.86, P = 0.157), operative bleeding (WMD 66.99 ml, P = 0.192) and hospital stay (WMD − 0.15 days, P = 0.766). The overall postoperative complication (relative risk, RR 1.08, P = 0.421) and mortality (RR 0.44, P = 0.195) were similar between two groups. Conclusions This meta-analysis indicated that bursectomy is time-consuming without increasing the number of harvested LNs. Although bursectomy can be safely performed without increasing complications and mortality, it does not prolong the OS and DFS of AGC patients, including patients with serosa-penetrating tumours. Therefore, bursectomy should not be recommended as a standard procedure for AGC. Electronic supplementary material The online version of this article (10.1186/s12957-018-1354-1) contains supplementary material, which is available to authorized users.
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- 2018
3. Endoscopic ultrasonography compared with multidetector computed tomography for the preoperative staging of gastric cancer: a meta-analysis
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Li Pu Xu, Shu Qiang Yuan, Xiao Jiang Chen, Yingbo Chen, Shi Chen, Bao Yan Zhu, Zhiwei Zhou, Xiaowei Sun, Yong Ming Chen, and Run Cong Nie
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medicine.medical_specialty ,Staging ,lcsh:Surgery ,Endoscopic ultrasonography ,Review ,lcsh:RC254-282 ,Endosonography ,Multidetector computed tomography ,03 medical and health sciences ,0302 clinical medicine ,Stomach Neoplasms ,Medicine ,Humans ,cardiovascular diseases ,Lymph node ,Neoplasm Staging ,Receiver operating characteristic ,business.industry ,Gastric carcinoma ,Cancer ,lcsh:RD1-811 ,medicine.disease ,lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,Prognosis ,Confidence interval ,digestive system diseases ,Meta-analysis ,medicine.anatomical_structure ,Oncology ,030220 oncology & carcinogenesis ,Relative risk ,cardiovascular system ,030211 gastroenterology & hepatology ,Surgery ,Radiology ,business - Abstract
Background The current study sought to perform a meta-analysis to compare the preoperative staging of endoscopic ultrasonography (EUS) and multidetector computed tomography (MDCT) in gastric carcinoma. Methods Articles published between January 1, 2000, and April 1, 2016, that compared EUS with MDCT were included, and data were presented as 2 × 2 tables. The sensitivities, specificities and summary receiver operating characteristic (ROC) curves for T and N staging were calculated using a bivariate mixed effects model. Data were weighted by generic variance and then pooled by random-effects modeling. Results Eight studies comprising 1736 patients were included in this meta-analysis. For T1 staging, the sensitivity value for EUS (82%) was significantly higher than that for MDCT (41%) (relative risk (RR): 2.06, 95% confidence interval (CI) 1.07–3.94; P = 0.030). For lymph node involvement, the sensitivity value for EUS (91%) was also significantly higher than that for MDCT (77%) (RR 1.14, 95% CI 1.05–1.23; P = 0.001). However, the specificity values of both EUS and MDCT were quite low, at 49 and 63%, respectively. No significant differences in T2–4 staging between EUS and MDCT were noted. Conclusion This meta-analysis indicates that EUS may be superior to MDCT in preoperative T1 and N staging. Additionally, the low specificity values of EUS and MDCT for N staging merits attention.
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- 2017
4. Outcome of colon cancer initially presenting as colon perforation and obstruction.
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Tsung-Ming Chen, Yen-Ta Huang, and Guan-Chyuan Wang
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COLON cancer diagnosis , *CANCER-related mortality , *HEALTH outcome assessment , *HOLES , *RECTAL cancer - Abstract
Background: Emergency complications of colon cancer include perforation and obstruction which were recognized as poor prognostic factors. Few studies have directly compared the outcomes of these two groups. In this study, we evaluated mortality and morbidity in patients with colon cancer initially presenting as perforation and obstruction. Methods: Newly diagnosed colon cancer cases initially presenting with perforation or obstruction at Tzu Chi General Hospital, Hualien, Taiwan, between 2009 and 2015 were included. Cases of iatrogenic perforation or perforation sites far away from the tumor sites and rectal (< 15 cm from the anal verge) cancer were excluded. Progression-free survival, local recurrence rate, distant metastasis rate, and overall survival were the evaluated outcomes. Results: Eighty-one patients met the selection criteria; 23 and 58 patients had perforation and obstruction, respectively, as the initial symptom. The median age was 72 years. The median tumor stage was stage IIIB. The 1-year and 3-year survival rates were 83.7 and 59.7%, respectively. The perforation group (PRG) and obstruction group (OBG) did not differ significantly in intensive care unit (ICU) stay rate (p = 0.147), sex (p = 0.45), comorbidities (heart, liver, and renal diseases and diabetes mellitus), median stage (p = 0.198), and overall survival (p = 0.328). However, PRG had a higher age at diagnosis (74 vs. 64 years, p = 0.037), a higher APACHE II score (12 vs. 7, p = 0.002), lower disease-free survival (p = 0.001), a higher recurrence rate (56.5 vs. 19%, p = 0.002), a higher distant metastasis rate (39.1 vs. 13.8%, p = 0.015), and a higher local recurrence rate (43.5 vs. 5.2%, p < 0.001) than did OBG. OBG had a higher two-stage operation rate (46.6 vs. 17.4%, p = 0.022). After adjustment for the tumor stage, comorbidity (chronic renal disease), body mass index (BMI), and adjuvant chemotherapy or radiotherapy in multivariate statistics, PRG had lower disease-free survival (p = 0.005) than OBG but overall survival was identical. Conclusion: For colon cancer initially presenting as perforation or obstruction, the PRG had poorer progression-free survival, a higher local recurrence rate, and a higher distant metastasis rate than did OBG. Overall survival did not differ between these two groups. [ABSTRACT FROM AUTHOR]
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- 2017
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5. Endoscopic ultrasonography compared with multidetector computed tomography for the preoperative staging of gastric cancer: a meta-analysis.
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Run-Cong Nie, Shu-Qiang Yuan, Xiao-Jiang Chen, Shi Chen, Li-Pu Xu, Yong-Ming Chen, Bao-Yan Zhu, Xiao-Wei Sun, Zhi-Wei Zhou, and Ying-Bo Chen
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ENDOSCOPIC ultrasonography ,MULTIDETECTOR computed tomography ,PREOPERATIVE care ,GASTRIC diseases ,META-analysis - Abstract
Background: The current study sought to perform a meta-analysis to compare the preoperative staging of endoscopic ultrasonography (EUS) and multidetector computed tomography (MDCT) in gastric carcinoma. Methods: Articles published between January 1, 2000, and April 1, 2016, that compared EUS with MDCT were included, and data were presented as 2 × 2 tables. The sensitivities, specificities and summary receiver operating characteristic (ROC) curves for T and N staging were calculated using a bivariate mixed effects model. Data were weighted by generic variance and then pooled by random-effects modeling. Results: Eight studies comprising 1736 patients were included in this meta-analysis. For T1 staging, the sensitivity value for EUS (82%) was significantly higher than that for MDCT (41%) (relative risk (RR): 2.06, 95% confidence interval (CI) 1.07-3.94; P = 0.030). For lymph node involvement, the sensitivity value for EUS (91%) was also significantly higher than that for MDCT (77%) (RR 1.14, 95% CI 1.05-1.23; P = 0.001). However, the specificity values of both EUS and MDCT were quite low, at 49 and 63%, respectively. No significant differences in T2-4 staging between EUS and MDCT were noted. Conclusion: This meta-analysis indicates that EUS may be superior to MDCT in preoperative T1 and N staging. Additionally, the low specificity values of EUS and MDCT for N staging merits attention. [ABSTRACT FROM AUTHOR]
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- 2017
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6. Preoperative pre-albumin predicts prognosis of patients after gastrectomy for adenocarcinoma of esophagogastric junction.
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Wen-xiu Han, Zhang-ming Chen, Zhi-jian Wei, and A-man Xu
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ESOPHAGOGASTRIC junction cancer , *ADENOCARCINOMA , *GASTRECTOMY , *DISEASE incidence , *DISEASE prevalence , *RETROSPECTIVE studies , *CANCER treatment - Abstract
Background: Adenocarcinoma of esophagogastric junction (AEG) was initially proposed in 1999 by Siewert. During recent decades, the incidence and prevalence of AEG were arising globally whereas the incidence of gastric cancer is gradually declining. Complete blood counting and liver function tests, as the routine examination of immune and nutritional status, were reported to be the predictors of overall survival (OS) in some tumors. However, little is known about the prognostic significance of these indexes in AEG patients. The purpose of this study was to assess the prediction of preoperative pre-albumin, hemoglobin, and prognostic nutritional index (PNI) for survival outcomes in AEG patients. Methods: A retrospective cohort of 101 AEG patients followed by radical surgery was recruited between January and July 2010. Clinical and laboratory data were obtained and used to evaluate the predictive value through survival analysis. Receiver operating characteristic (ROC) curve analysis determined 200 mg/L, 120 g/L, 5 cm, and 51 as the cutoff values of pre-albumin, hemoglobin, tumor size, and PNI, respectively. Results: Univariate analysis revealed that AEG patients with hemoglobin =120 g/L, albumin =40 g/L, prealbumin =200 g/L, PNI =51, and tumor size <5 cm had longer OS (P < 0.05). Additionally, pre-albumin, tumor size, and TNM stage were demonstrated to be independent prognostic indicators by multivariate analysis with Cox regression, and the performance of pre-albumin for predicting OS in AEG patients was further identified by ROC curves (P = 0.006). Conclusions: Preoperative pre-albumin was an independent prognostic factor, and a high level of prealbumin predicted longer OS in AEG patients. [ABSTRACT FROM AUTHOR]
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- 2016
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7. Transpapillary biliary biopsy for malignant biliary strictures: comparison between cholangiocarcinoma and pancreatic cancer.
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Wei-Ming Chen, Kuo-Liang Wei, Yi-Shing Chen, Pey-Jium Chang, Shui-Yi Tung, Te-Sheng Chang, Hao-Chun Huang, Chein-Heng Shen, Yung-Yu Hsieh, and Cheng-Shyong Wu
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BILIARY tract , *BIOPSY , *CHOLANGIOCARCINOMA , *PANCREATIC cancer , *HEALTH outcome assessment - Abstract
Background: Tissue sampling for biliary stricture is important for differential diagnosis and further treatment. This study aims to assess the differences of transpapillary biliary biopsy for malignant biliary strictures between cholangiocarcinoma and pancreatic cancer. Methods: From January 2010 to December 2013, we retrospectively studied 79 patients who suffered from biliary strictures and received transpapillary forceps biopsy after sphincterotomy for tissue sampling. The diagnostic sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of forceps biopsy were calculated in all cases for both cholangiocarcinoma and pancreatic cancer patients. Possible factors that distinguish malignant strictures from benign strictures and which could affect the accuracy of tissue sampling were analyzed. Results: There are 65 malignant and 14 benign biliary stricture patients enrolled. The malignant group has a significantly higher serum bilirubin level than the benign group, but age, clinical presentation, level of serum carcinoembryonic antigen (CEA), carbohydrate antigen (CA) 19-9, and alkaline phosphatase are not. The sensitivity, specificity, PPV, and NPV of forceps biopsy for biliary stricture are 53.85, 100, 100, and 31.82 %, respectively. The cholangiocarcinoma group has a higher sensitivity (73.53 versus 29.17 %, p < 0.001), older age, lower CA 19-9 level, and more common hepatic duct strictures than the pancreatic group. The age, serum CEA, CA 19-9 and the alkaline phosphatase level, serum bilirubin level >10 mg/dL, tissue sampling ≧3 are not significant factors affecting diagnostic accuracy in forceps biopsy for pancreatobiliary strictures. There is neither major bleeding nor perforation in our study. Conclusions: Transpapillary forceps biopsy of biliary strictures after sphincterotomy for tissue sampling is safe and a significantly higher sensitive method in cholangiocarcinoma but not in pancreatic cancer. [ABSTRACT FROM AUTHOR]
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- 2016
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8. Gastrointestinal metastasis from primary sarcomatoid carcinoma of the lung: a case report and review of the literature.
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Chun-Hsien Chen, Wei-Ming Chen, Shui-Yi Tung, Cheng-Shyong Wu, Wei-Lin Tong, Kam-Fai Lee, and Kuo-Liang Wei
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LUNG cancer patients , *GASTROINTESTINAL cancer treatment , *ABDOMINAL pain , *CALCIUM-binding protein genes ,RISK of metastasis ,PAIN risk factors - Abstract
Gastrointestinal metastases in lung cancer are extremely rare. The report presents a rare case of primary lung sarcomatoid carcinoma with both gastric and colonic metastases, and reviews the literature about endoscopic presentation of colonic metastases. [ABSTRACT FROM AUTHOR]
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- 2015
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9. Osteomyelitis of the femur mimicking bone tumors: a review of 10 cases.
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Po-Yen Huang, Po-Kuei Wu, Cheng-Fong Chen, Fang-Tsai Lee, Hung-Ta Wu, Chien-Lin Liu, Tain-Hsiung Chen, and Wei-Ming Chen
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OSTEOMYELITIS ,C-reactive protein ,BONE diseases ,GLOBULINS ,MAGNETIC resonance imaging ,BIOPSY ,STAPHYLOCOCCUS aureus - Abstract
Background The clinical symptoms and radiographic appearance of osteomyelitis can mimic those of bone tumors. Methods We reviewed 10 patients with osteomyelitis of the femur who were initially diagnosed as having bone tumors and were subsequently transferred to our institution. Results Nocturnal pain of moderate intensity occurred in seven patients, and all 10 patients had elevated C-reactive protein levels. The radiographic findings included the following: a permeative, moth-eaten osteolytic lesion in six patients, an osteolytic lesion with sclerotic borders in three patients, and cortical destruction with pathological fracture in one patient. Magnetic resonance imaging was performed for eight patients, and only one had a positive penumbra sign. All patients underwent a surgical biopsy to confirm the final diagnosis for histological analysis and cultures. Klebsiella pneumoniae was detected in six patients and Staphylococcus aureus, the most common organism in osteomyelitis, was detected in three. Recurrence of infection occurred in five patients following debridement surgery; of these three had a Klebsiella pneumoniae infection. All patients received antibiotic treatment for an average of 20.4 weeks (range, 4 to 44) and surgical treatment an average of 1.8 times (range, 1 to 4). At the final follow-up, all patients were fully recovered with no signs of infection. Conclusions When used in combination, clinical examinations, laboratory data, and radiographic findings can reliably distinguishing osteomyelitis from bone tumors. [ABSTRACT FROM AUTHOR]
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- 2013
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10. Brachial plexus palsy after a left-side modified radical mastectomy with immediate latissimusdorsi flap reconstruction: report of a case.
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Jun-Dong Wu, Wen-He Huang, Zi-Yi Huang, Ming Chen, and Guo-Jun Zhang
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BRACHIAL plexus ,WOUNDS & injuries ,MASTECTOMY ,BREAST cancer patients ,BREAST surgery ,ANESTHESIA - Abstract
Brachial plexus injury is a rare complication during operation and anesthesia; it can occur as a result of various mechanisms such as inappropriate positioning, over-abduction and stretching the upper limbs. Brachial plexus injury can cause the poor function of the upper limb before recovery, and sometimes serious injury is unable to completely recovered the function permanently. Here, we report a female breast cancer patient who sustained a left brachial plexus palsy after modified radical mastectomy with immediate breast reconstruction with latissimusdorsi flap (LDF). The patient had fully recovered with normal function of her left upper limb six months postoperation after conservative treatment. [ABSTRACT FROM AUTHOR]
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- 2013
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11. Chondroblastoma associated with aneurysmal cyst of the navicular bone: a case report.
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Zhenhua Fang and Ming Chen
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CHONDROBLASTOMA , *ANEURYSMS , *NAVICULAR disease , *CYSTS (Pathology) , *RARE diseases , *LUNG cancer , *BONE grafting - Abstract
Chondroblastoma is a rare tumor. It is usually benign; however, it can have an aggressive course before or after operative treatment, even resulting in pulmonary metastases. The foot is a rare location for chondroblastoma, and to our knowledge, chondroblastoma occurring in the navicular bone has not been reported previously in the English literature. We describe a case of navicular chondroblastoma case associated with an aneurysmal bone cyst. Treatment consisted of aggressive curettage, phenolization, and bone allograft. The patient was able to resume normal activities after treatment, and there was no recurrence of the chondroblastoma during a follow-up of 3 years. [ABSTRACT FROM AUTHOR]
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- 2013
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12. Decreased expression of survivin, estrogen and progesterone receptors in endometrial tissues after radiofrequency treatment of dysfunctional uterine bleeding.
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Geping Yin, Tongyu Zhu, Juan Li, Ming Chen, Shujun Yang, and Xiaoli Zhao
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SURVIVIN (Protein) ,APOPTOSIS inhibition ,GENE expression ,RADIO frequency ,PROGESTERONE - Abstract
Background: The purpose of the research is to study the histopathology and expression of survivin, estrogen and progesterone receptors (ER/PR) in the endometrium of patients with dysfunctional uterine bleeding (DUB) treated with radiofrequency endometrial ablation (REA). Methods: A total of 98 DUB patients were enrolled in this case-control study. Among them, 66 underwent REA treatment and 32 optioned for hormone therapy as the control group. Immunohistochemical analysis for survivin, ER and PR expression was carried out on endometrial tissue samples collected before and 6 to 7 months after treatment for both groups. Results: Both hormone and REA treatment ameliorated menstrual bleeding of DUB patients, with the latter showing a significantly higher effective rate. Endometrial surface tissue was replaced by fibrosis tissue in the REA treatment group. REA treatment also significantly reduced the expression of survivin, ER, and PR. Endometrial surface tissues collected from the hormone-treated control group neither showed any apparent morphological alteration nor in the expression of those receptors. Conclusions: REA treatment changed endometrial surface tissue type from gland rich to gland poor, and significantly decreased the expression of survivin, ER, and PR. This may be an important contributing mechanism for the long-term curative effect and prevention of DUB recurrence. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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