Search

Preeclampsia is a hypertensive disorder of pregnancy causing a high rate of both maternal and neonatal morbidity and mortality. Recent reports suggest that free radical-induced endothelial cell injury might be an etiologic factor in the pathogenesis of preeclampsia. The aim of this study was to determine the effect of antioxidants such as E and C vitamins on the prevention of preeclampsia. Materials and Methods: This clinical- trial study was conducted in the year 2009 in the clinical centers of Lorestan university of medical sciences. 160 nulliparous women with the age range of 18 to 35 without any risk factors for preeclampsia were divided into two groups. The first group received oral vitamin E 400 IU/day, and vitamin C 1000 mg/day with iron tablets during the 20th to 24th weeks of pregnancy while the control group received only iron tablets. Finally, the data was analyzed using descriptive statistics and frequency distribution tables. Results: Incidence of preeclampsia in the control group was 17.5% and in the case group it was 5% that was statistically significant. The means of systolic pressure before and after intervention in the control group were 99.43 7.8, and 12.44 19.1 while in the case group they were 99.3 8.3 and 106.12 13.25. Diastolic pressure means before and after intervention in the control group were 62.7 13.6 and 62.7 4.7. Conclusion: As the results showed, use of antioxidants can clearly reduce the risk of preeclampsia, and can reduce the mean systolic and diastolic pressure.

Lorzadeh N1, Ghafarzadeh M1, Vahabi S2, Lashgar-ara GhR3 1. Assistant professor, Department of gynecology, Faculty of medicine, Lorestan University of medical sciences 2. Assistant profwssor, Department of anesthesiology, Faculty of medicine, Lorestan University of medical sciences 3. General practitioner, Information and drugs center of Lorestan health department Abstract Background: In this study we evaluate the outcome of pregnancy in the patient that received M. MR vaccine during M.MR vaccination program on Lorestan of fall 2003. Materials and methods: This is a descriptive epidemiologic study, we evaluated all of women that vaccinated with M.MR vaccine during pre and post conception. We collected and analyzed all of information like prognosis of pregnancy, congenital rubella syndrome, gestational age weigh of newborn. Results: In 92 pregnancy women infected with MMR vaccine, the prognosis of pregnancy clearly seen 88 pregnant women (96%) 73 (83%) had normal and healthy newborn infant and 5 (6%) had spontaneot abortion and 10 pregnant women (11%) had legal abortion. Mean gestational age at birth was 39.5 ± 2.1 and weigh of newborn was 3257 ± 535 grams. None of the live born infants had not congenital rubella syndrome. Conclusion: In this study we showed M.MR vaccination during pregnancy had not any complication pregnancy. But pregnancy yet is an contraindication for M.MR vaccibnation, vecause this patient theories have risk of congenital rubella syndrome.

Background: Post partum psychosis is a mood disorder which starts 2 or 3 weeks after delivery. In acute form, the symptoms of this disorder are so obvious that the sick mother doesn’t want to take care of her child in some cases, she wants to hurt either the child or herself or both (the child & the mother). It seems that there are some psychosocial factors that cause this problem to occur. Material and methods: The present study aims to survey the effect of social, cultural, economical and related factors on the post partum psychosis in 2003-2005. The study was cross sectional. The study included all the women who immediately return to the one of the clinical and educational centers for psychosis symptoms. All the women came to the clinics with one of the symptoms of mood disorder 3 to 12 weeks after their delivery. They were examined by psychiatrists. They were also interviewed by clinical psychologists. Those who recognized as having acute depression and psychotic symptoms were included in the study. The data were analyzed using “SPSS” software. Results: Most of the subjects were in the range of 20-30 years old. They were housewives. In most case, they gave birth to a female newborn and the delivery was done in a normal way. Most of the patients declared that they had unplanned pregnancy. 29.6% of the patients had mental disease background. 9.1% had major depression, 5.6% had dysthymic disorder. 18.5% of the subjects had physical disease like UTI, hyper thyroid and seizure. Conclusion: There was a significant relationship between post partum psychosis and variables such as age, education, job, and disease background, number of delivery and lack of child acceptance. It is suggested that for prevention of post partum psychosis, there should be a very suitable situation for pregnant mothers. Moreover by planning and designing educational programs, we could provide the proper background for child birth in the family.

Introduction: Considering the high incidence of preterm labor and its known complications, and that human myometrium contains receptors for human chronic gonadotropin (hCG) and that hCG can inhibit myometrial contractions on vitro, made me study treating effects of hCG on preterm labor. This clinical trial study was carried out to compare the effect of hCG, and magnesium sulfate (mgso4) on prevention of preterm labor Materials and methods: The study group included 101 women at weeks 22-35 of the gestation with intact membranes and cervical dilatation less than 4cm in preterm labor in referrals of obstetric – clinics in Khorramabad city during the years 2001-2003. The case and control groups were treated with hCG protocol of the dosage consisted of one single dose of hCG 5000 1v and 10000 units of hCG in 5oo dextrose as a drip of 20 drops per minute. Treatment continued until preterm labor arrested and then complications of mother and fetus were recorded. On condition of a successful cease of labor, the patients were discharged and followed uptill deliven time. Findings: Both groups were similar to each other regarding maternal age, gravity, and gestational age . Mean delay of labor was 22/68 days after administration of hCG and 24/27 days for (mgso4) that was not significant. The number of newborns that admitted in NICU were 9 (18%) for hCG and were 9(17/8%) for magso4. Mean weight at labor was 2334gr and 2287gr for hCG and mgso4. The complaint rate was 100% and 0% for magnesium sulfate and hCG groups respectively (P