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Your search keyword '"Wyrzykowski, Dariusz"' showing total 7 results
Start Over Author "Wyrzykowski, Dariusz" Journal zeitschrift fur anorganische und allgemeine chemie
7 results on '"Wyrzykowski, Dariusz"'

1. Structure, Physicochemical and Biological Properties of an Aqua (2,2′,2′′-Nitrilotriacetato)-oxidovanadium(IV) Salt with 4-Methylpyridinium Cation

Author

Tesmar, Aleksandra, primary, Wyrzykowski, Dariusz, additional, Kazimierczuk, Katarzyna, additional, Kłak, Julia, additional, Kowalski, Szymon, additional, Inkielewicz-Stępniak, Iwona, additional, Drzeżdżon, Joanna, additional, Jacewicz, Dagmara, additional, and Chmurzyński, Lech, additional

Published
2017
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7. Electrochemical and Biological Studies on Reactivity of [VO(oda)(H2O)2], [Co(oda)(H2O)2]·H2O, and [Ni(oda)­(H2O)3]·1.5H2O Towards Superoxide Free Radicals

Author

Wyrzykowski, Dariusz, Inkielewicz ‐ Stępniak, Iwona, Czupryniak, Justyna, Jacewicz, Dagmara, Ossowski, Tadeusz, Woźniak, Michal, and Chmurzyński, Lech

Subjects
*SUPEROXIDES, *ELECTROCHEMICAL analysis, *METAL complexes, *OXIDATION, *PLATINUM electrodes
Abstract

The reactivity of superoxide free radicals (O2 ·-) generated electrochemically towards the oxydiacetate metal complexes, namely [VO(oda)(H2O)2], [Co(oda)(H2O)2] ·H2O, and [Ni(oda)(H2O)3] ·1.5H2O (oda = oxydiacetate) was examined by cyclic voltammetry. The measurements were carried out in DMSO solution using a platinum electrode. Based on the height of the anodic peak Ea that corresponds to electrochemical oxidation O2 ·- → O2 + e, in the absence and in the presence of the compounds in the mixture, their O2 ·- scavenge ability was assessed. The influence of the type of the complex was briefly discussed. H2O2 was used to induce cellular injury in a mouse hippocampal cell line (HT22). The cytoprotection of chemical compounds was tested at the mitochondrial (MTT test) and plasma membrane level (LDH leakage). Dose-dependent effect (10 and 100 μM of the complex) of investigated compounds was observed. [ABSTRACT FROM AUTHOR]

Published
2013
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