1. [Double-pump implantation chemotherapy for hepatic metastasis from colorectal cancer]
- Author
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Jianmiao, He, Yongdong, Pu, Zhidong, Zhu, Zhiyu, Cao, Bo, Yang, and Liguo, Dong
- Subjects
Adult ,Male ,Portal Vein ,Liver Neoplasms ,Infusion Pumps, Implantable ,Therapeutics ,Middle Aged ,Hepatic Artery ,Drug Therapy ,Humans ,Infusions, Intra-Arterial ,Female ,Colorectal Neoplasms ,Infusions, Intravenous ,Aged - Abstract
To evaluate the value of infusion chemotherapy by pump implantation via hepatic artery or portal vein or both (double-pump chemotherapy, DPC) for hepatic metastasis from colorectal cancer.Thirty patients with hepatic metastasis from colorectal cancer were divided into three groups: 1. Group I-DPC (12 patients). 2. Group II-hepatic artery implantation chemotherapy (10 patients) and 3. Group III-portal vein implantation chemotherapy (8 patients).Response rate was 66.7% in group I, 60% in group II and 37.5% in group III. The 0.5-, 1-, 2-year survival rates were 100.0%, 75.0%, 41.7% in group I, 90.0%, 60.0%, 30.0% in group II and 87.5%, 50.0%, 25.0% in group III.Double pump implantation chemotherapy is effective in treating hepatic metastasis from colorectal cancer. It is better than hepatic artery or portal vein pump-implantation chemotherapy alone.
- Published
- 2002