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This study aimed to investigate the effect of different concentrations of different water salinity (36, 17, 8, 4, 2 ppt. and salinity level is less than 1ppt.) on growth performance and survival rate (%) of sea bass fry Dicentrarchus labrax. One thousand and two hundred sea bass fry were randomized stocked at twelve indoor tanks; 4 m3 each (two replicate/treatment), with an average initial body weight of (2 ± 0.30 g/fish) at the rate of 100 fish / tank. Fish in each tank were hand-fed with commercial diet (40 % crude protein and 485.582 Kcal GE/ 100 g diet). Fish were fed daily at a rate of 15, 10, 5, 4 and 3% of the body weight daily for the (1:2.2); (2.2:3.84); (3.84:9.2); (9.20:12.70) and (12.70) g/fish : until the end of the experiment, respectively. The daily allowances were divided into three meals at 8.00 am; 11.00 am and 2.00 pm. Fish were fed six days a week throughout the experimental period (167 days). The daily amount of feed was re-adjusted every two weeks according to the actual fish biomass in the tanks. The highest significant values of growth performance parameters were observed when sea bass fry were reared at salinities 8 and 36 ppt. Weight gain of the other treatments were negatively affected (p