This report discusses Egypt's historical and modern strategic orientation in Africa, including the Nile Basin and the Horn of Africa. The continent was viewed as a source of trade, influence, and power and a potential threat to Egypt's Nile Valley civilization. In the post-independence period, Africa is witnessing constant tensions and conflicts, exacerbating its complex economic, political, and humanitarian crises. Within this context, global and regional powers are constantly vying for control, driven by Africa's geostrategic importance. However, neoliberal policies since the 1970s, as well as the repercussions of the Arab Spring in 2011, led Egypt to move away from the periphery of its African circle, allowing the rising powers in Africa and the Middle East to influence Egypt's strategic position there. This development raises critical questions: How has Egypt's African role developed? What are the current challenges? How can Egypt use its soft power effectively in Africa? The report discussed these questions, pointing out the essential factors and dimensions that shaped its strategic direction south of its national borders. It also shows how Egypt's role in Africa has declined in recent decades, including the repercussions of soft power dynamics in light of multifaceted challenges. These major soft power dynamics are water security threats and international and regional competition. In trade and investment with Africa, the report stresses the need for Egypt to formulate comprehensive strategies and participate in regional partnerships. It considers Egypt's historical experience would help to catalyze the adaptation of policies to evolving circumstances; Egypt can proactively secure its interests and exercise its influence in the evolving landscape in Africa. In the end, the report concluded that Egypt still has the concern and the potential to navigate the challenges faced by its role in the last decade, specifically as it transformed into more stable politically and economically. It might take the initiative to mediate between African competitors locally and regionally, as is the case in Sudan and Western Africa. [ABSTRACT FROM AUTHOR]