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In the paper the author describes the fine structure of terminal vascular branches in various organs of animals and human under normal physiological and experimental conditions and some pathological processes. Vesicles in various functional states of the capillaries are described as well as some more rarely encountered inclusions such as fatty drops, lipofuscyne granules anf glycogen storages, Microruptures of the vessels are found in inflammatory processes as well as disappearance of membranes of some fenestrations in the capillaries of the thyroid gland in thyreotoxicosis.