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The authors examined age peculiarities in the microcirculation bed of the intestinal mucosa in 20 individuals, aged from 0 to 83 years. The vessels were manifested by injection with Indian ink-gelatine mass. There was also complication of their angioarthitectonics parallel to the age and progressive thickening of glandular layer and enlargement and clongation of the villi. The arterial sources were increased and varified. Villus-capillary nest was changed in vertical direction. Togethe with this the outflow venous system was complicated as over the basal plexus a second venous plexus was formed-over the basis of the villi. The mucosa was enriched with arterio-venous anastomosis. Maximal development of the microcirculatory system was found at the end of the third decade, after which their reduction begins. This process was more manifested after the sixth decade, when the blood vessels were folded and received uneven constructions and dilatations, and then the capillary nest is rearranged and simplified.