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key to satisfy people’s demand for consumption of livestock and poultry products. This study focused on the strategic requirements of ensuring food security and achieving sustainable protein supply, and analyzed the utilization status of protein feed resources and summarized the major problems in protein feed supply. Based on the protein feed resources in China and the potential of protein supply in the international market, this article analyzed the potential for substituting soybean meal in our country. It is expected that by 2035 the soybean imports will have reduced 58.8 million tons compared with 2020 by expanding the planting, increasing the income of oil crops, developing new feed resources, utilizing conventional protein feed resources, efficiently, optimizing the planting structure of forage crops, as well as improving the efficiency of livestock and poultry protein conversion. It is suggested that future efforts should be focused on tapping potentials and expanding resources, strengthening scientific and technological support, also carrying out appropriate import by imptementing major projects such as increasing crop and forage production, improving quality and efficiency of unconventional protein feed resources, and developing new protein feed resources. In addition, financial support should be increased and the international market effectively exploited, in order to promote soybean meal substitution and ensure national food security.

Objective To investigate the clinical characteristics and management strategies for multiple endocrine neoplasia 1 （MEN1） during pregnancy. Methods The gender, age, detailed medical history, clinical symptoms and signs, laboratory, imaging and pathological examination data of a MEN1 proband were collected. And the demographic characteristics, clinical characteristics and auxiliary examination of 20 members from the MEN1 family were also collected. MEN1 cases during pregancy were searched from PubMed and Wanfang Data using the keywords of “Multiple Endocrine Neoplasia Type 1“and“Pregnant” in both English and Chinese. Results The main clinical manifestations of the MEN1 proband were pituitary microadenoma （galactorrhea, elevated prolactin）, pancreatic endocrine tumor （hypoglycemia） and parathyroid adenoma （asymptomatic, elevated parathyroid hormone and blood calcium）. Gene analysis confirmed that exon 9 of MEN1 gene （CGA > TGA, Arg415Term） was the pathogenic mutated gene. The father and daughter of the proband carried this pathogenic mutation and had hyperparathyroidism. After drug treatment for pituitary microadenoma and surgical treatment for pancreatic endocrine tumor and parathyroid adenoma, the proband was pregnant and delivered a female infant successfully. During this period, there was no recurrence of galactorrhea and hypoglycemia, the levels of parathyroid hormone and blood calcium were stable, and fetal growth and development were normal. A total of seven pregnant cases of MEN1 in English literature and one in Chinese literature were retrieved. It was found that all MEN1 patients developed onset of diseases at childbearing age. As for clinical symptoms, parathyroid, pancreas and pituitary were the most involved. Most patients had family history and MEN1 gene mutation. In terms of pregnancy outcome, seven patients delivered successfully under strict condition monitoring and treatment. Conclusion Clinicians’ active detection, diagnosis and treatment will help to improve the prognosis of MEN1 patients and their offspring.

Cotton is a relatively salt-tolerant crop, but high salt stress leads to a significant decline in cotton yield and fiber quality. Mining the genes involved in salt-tolerance and illuminating the molecular mechanisms that underlie this resistance is of great importance in cotton breeding programs. Here, we identified an AP2/ERF transcription factor GhTINY2 in the transcriptome database from cotton treated with salt, and the relative expression level of GhTINY2 was reduced by salt. Subsequently, the salt-resistant phenotype and physiological indicators of the GhTINY2-overexpression Arabidopsis were analyzed. The results revealed that the GhTINY2-overexpression Arabidopsis had a significant decrease in seed germination rate, the content of proline, soluble sugar, and chlorophyll under salt stress, leading to more severe leaf wilting compared with WT. RNA-seq data from GhTINY2-transgenic Arabidopsis revealed that differentially expressed genes (DEGs) were enriched in a series of biological processes, including chlorophyll metabolism and response to stimulus, and the relative expression level of these DEGs significantly was down-regulated. Moreover, the silence of GhTINY2 in cotton through Virus-induced gene silencing (VIGS) assay showed that TRV:GhTINY2 had a significant increase in chlorophyll and proline content, leading to improved salt tolerance compare with TRV:00. In conclusion, these findings suggest that GhTINY2 was an important gene in cotton that negatively regulated salt stress resistance, and it was expected to create salt-tolerant cotton materials using GhTINY2 gene by modern genetic engineering technology in the future. [ABSTRACT FROM AUTHOR]

Nickel chloride (NiCi2), as a cathode material of high potential thermal battery, its poor conductivity limits Is application in thermal battery. In this study, cuprous ion doped nickel chloride (NiCl2-Cu.r) was prepared vasa liquid-phase mixing and low temperature calcination process. NiCl2-Cu5 possesses the best electro- chemical performance. Compared wk. NiCl2, NiCl2-Cu5 exhibits the advantages of high voltage and high specie- c energy. Especially at the current dimity of 500 cm2, NiCl2-Cu5 shows a high specific energy of 724 kg, which Ls about 82% higher than that of NiCl2. Pulse test shows that NiCl2-Cu5 cathode material has lower internal resistance and can aureate ohm polarization doing discharge, thus realizing high specific energy output. This work provides a new approach for the development of high-performance cathode materials for thermal battery. [ABSTRACT FROM AUTHOR]

A novel anti-aging silane coupling agent (Si-GD) was synthesized by the ring-opening reaction of p-phenylenediamine and 3-glycidoxypropyltriethoxysilane based on the mechanism of aging protection and coupling agent modification on silica. Natural rubber/silica composites were modified by Si-GD. The effects of different amounts of Si-GD on crosslinking density, micro-morphology, mechanical properties, aging resistance and wear resistance on natural rubber/composites were studied. The results show that the tear strength, tensile strength, modulus, resilience, Shore A hardness and hot air aging resistance of Si-GD modified composites are significantly increased. The natural rubber/silica composites modified with 4 phr of Si-GD has better wear resistance than that modified with 4 phr of Si-69. [ABSTRACT FROM AUTHOR]

Pharmaceutically active compounds(PhACs) have become a class of new pollutants in the environment after extensive production and use of PhACs in China. To investigate the pollution characteristics of PhACs in Guangdong Province, raw sewage was collected from 186 sewage treatment plants in 21 cities, including 178 townships and administrative districts in Guangdong Province. The pollution levels of ten typical PhACs in influent water of sewage treatment plants were analyzed using automatic solid phase extraction and high performance liquid chromatography-triple quadrupole mass spectrometry. The spatial distribution characteristics of PhACs in Guangdong Province were fully revealed, and the potential ecological risks of PhACs were evaluated. The results showed that PhACs were detected in all wastewater plants, and the mass concentration of PhACs ranged from 21.00 to 9558.25 ng·L -1 . Metoprolo, acetaminophen, bezafibrate, and caffeine were the main pollutants. In terms of spatial distribution, the average mass concentration of ΣPhACs in various regions of Guangdong Province was in the following order:Pearl River Delta>North Guangdong>East Guangdong≈West Guangdong. When the mass concentration of ΣPhACs was over 2500 ng·L -1 in the influent water of sewage treatment plants, the concentration of PhACs in effluent was estimated according to the sewage disposal technology. The ecological risk of PhACs was carried out based on the effluent. The results revealed that the ecological risk of PhACs was low in Guangdong Province, and the risk of bezafibrate was moderate in the cities of Shaoguan, Jiangmen, and Shenzhen. The highest ecological risk of ΣPhACs was located in Shaoguan.