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Liver is one of the important edible byproducts of livestock and poultry. It has high nutritional value and a long history of human consumption in China. However, liver, when used as food, has the problems of off-flavor, poor texture, and high risk of residual harmful substances, which results in low overall food utilization rate. This not only reduces the overall profit of the meat processing industry, but also causes a waste of resources. This review focuses on recent research on the nutrition, flavor, texture, and quality improvement of livestock and poultry liver. Moreover, the defects and blind spots in current research are summarized. It is expected that this review will be helpful for further research and provide a basis for the high-value utilization of livestock and poultry liver.

ObjectiveTo investigate the impact of acute respiratory infections in children under 12 years old in Pudong New Area， Shanghai from 2019 to 2023.MethodsAcute respiratory infection samples of children under 12 years old from three sentinel hospitals in Pudong New Area， Shanghai from 2019 to 2023 were collected， and 42 respiratory infection pathogens， including influenza virus， adenovirus， parainfluenza virus， respiratory syncytial virus， human enterovirus/rhinovirus， human pulmonary virus， human bokavirus， coronavirus （229E， HKU1， NL63 and OC43）， and novel coronavirus， were detected with microfluidic chips. The situation of acute respiratory infections among outpatient and inpatient children in this area was analyzed for the before the implementation of non pharmacological intervention measures （2019.12‒2020.1）， during the period of non pharmacological intervention measures （2020.2‒2022.12）， and after non pharmacological intervention measures （2023.1‒2023.6）.ResultsFrom 2019 to 2023， a total of 1 770 samples were collected， and 445 pathogens were detected， with a detection rate of 25.14% （445/1 770）. The main pathogens detected during the study period were influenza virus： 8.70% （154/1 770）， respiratory syncytial virus： 4.41% （78/1 770）， human enterovirus/rhinovirus： 2.66% （47/1 770）， human adenovirus： 2.49% （44/1 770）， and parainfluenza virus： 2.20% （39/1 770）. Before the implementation of non pharmacological intervention measures， outpatients were primarily infected with influenza， parainfluenza virus， and respiratory syncytial virus， with detection rates of 8.09%， 4.49%， and 4.04%， respectively； inpatients were mainly infected with influenza， respiratory syncytial virus， and parainfluenza virus， with detection rates of 4.49%， 3.82%， and 3.15%， respectively. During the period of non pharmacological intervention measures， influenza， rhinovirus and respiratory syncytial virus were the main viruses detected in the samples of outpatient children， with detection rates of 4.04%， 3.60%， and 2.47%， respectively； inpatient samples mainly detected respiratory syncytial virus， rhinovirus， and influenza virus， with detection rates of 3.60%， 2.02%， and 1.80%， respectively. After non pharmacological intervention measures， influenza， rhinovirus and respiratory syncytial virus were the main pathogens detected in the outpatients， with detection rates of 9.89%， 2.92% and 2.02%， respectively； influenza， respiratory syncytial virus， and rhinovirus were the main pathogens detected in inpatient children， with detection rates of 6.29%， 1.57%， and 1.35%， respectively.ConclusionThe prevalence of pathogens related to acute respiratory infections in children is influenced by non pharmacological preventive measures.

Vitamin C is an essential micronutrient for human and its deficiency will lead to scurvy. In recent years, as a new therapeutic strategy, high dose intravenous vitamin C(HDIVC) has been widely studied in critical cared diseases. In this review, we summarized the progress of HDIVC in sepsis, including its research history, rationality of usage, controversy and prospect, problems and outlook. The application of HDIVC in critical cared diseases underwent three periods: early, preheating and outbreaking period. Given the reduction of vitamin C in critical diseases, it requires rapid intravenous supplementation. We confirmed the therapeutic efficacy of HDIVC in COVID-19 and severe acute pancreatitis respectively. It is well known that HDIVC has effect of suppressing inflammatory responses, stabilizing the circulation and improving the immunity. But the application of HDIVC in critical cared diseases is still controversial, for the opposing findings in multiple large-scale randomized controlled trials. Future studies should be better to pay further attention on the dose and time of vitamin C and vitamin C plasma concentration monitoring.

Objective To evaluate the effect of double filtration plasmapheresis (DFPP) on patients with hyperlipidemic acute pancreatitis (HL-AP). Methods The clinical data of the patients with hyperlipidemic severe acute pancreatitis (HL-SAP) or moderately severe acute pancreatitis (HL-MSAP) from January 2019 to May 2022 were collected. The patients were divided into two groups,the control group received conventional treatment, DFPP group received DFPP treatment on the basis of conventional treatment. Results Compared with the control group, the following parameters changed significantly in DFPP group, triglyceride (TG), alanine aminotransferase (ALT) and aspartate aminotransferase (AST) decreased on day 1 and 2, estimated glomerular filtration rate (eGFR) increased on day 1, 2, 3 and 5, leukocyte and neutrophil counts decreased on day 1 and 2, hemoglobin (HGB) decreased on day 1, 2, and 3, C-reactive protein (CRP) decreased on day 1, 2, 3, 5, and 7. And the patients in DFPP group receiving mechanical ventilation decreased compared with that in control group. Conclusion Compared with conventional treatment, DFPP can reduce plasma TG faster, improve lung, liver and kidney function, reduce inflammatory markers, and facilitate early fluid recovery.

Lipid oxidation and degradation in instant meatballs stored for different periods of time (0, 1, 2, 3, 4 and 5 days) were investigated by measuring peroxide value (POV), thiobarbituric acid reactive substances (TBARS) value, carbonyl value and diene value. The changes in the fatty acid composition of instant meatballs during storage were analyzed by gas chromatography-mass spectrometry (GC-MS). The evolution of volatile flavor compounds was studied by headspace-solid phase microextraction gas chromatography-mass spectrometry (HS-SPME-GC-MS) combined with calculation of odor activity value (OAV) and sensory evaluation. The results showed that eating quality attributes such as flavor and texture continued to decline during storage. Off-flavor appeared on the 4th day, and then quality deterioration was accelerated. The POV increased significantly during the early stage (0–3 days), but did not change significantly at the later stage (3–5 days). The TBARS value first increased slowly (0–4 days) and then dramatically (4–5 days). The carbonyl and diene values showed an upward trend during storage, indicating an increase in the degree of lipid oxidation. During storage, the proportion of unsaturated fatty acids (UFA) especially polyunsaturated fatty acids (PUFA) was significantly reduced. A total of 36 volatile flavor compounds with OAV ≥ 0.1 were detected. Among of them, the number (15) of aldehydes was highest. The OAVs of aldehydes and alcohols accounted for a high proportion (79.73%–87.58% and 10.15%–16.64%, respectively) of the total. Four and two classes of odor-active compounds were significantly correlated with lipid oxidation and sensory score for flavor, respectively.

The study aimed to investigate the dynamic changes of metabolites in beef high rib with different dry-aging periods by non-targeted metabolomics based on ultra-high performance liquid chromatography-mass spectrometry (UPLC-MS). Multivariate statistical analysis and metabolic pathway analysis were performed on the metabolites. The results showed that 41 differential metabolites were identified in dry-aged beef, including 21 amino acids, 16 fatty acids, 2 nucleotides and 2 other metabolites. The types and relative contents of differential metabolites increased significantly with prolonged aging time. Five key metabolic pathways were identified, including purine metabolism; fatty acid degradation; alanine, aspartate and glutamate metabolism; arginine and proline metabolism; and the tricarboxylic acid (TCA) cycle, which could promote the formation of flavor and nutrients in dry-aged beef.

In this study, the effect of Mg2+ on the physiochemical, structural and gel properties of mutton myofibrillar protein was studied. The results indicated that with an increase in Mg2+ concentration (0, 0.01, 0.02, 0.03, 0.04 and 0.05 mol/L), the physicochemical properties of mutton myofibrillar protein (MP) including solubility, emulsification activity, emulsion stability and particle size increased significantly (P < 0.05), the absolute value of the zeta potential decreased, the proportion of β-sheet increased significantly (P < 0.05), and surface hydrophobicity increased significantly (P < 0.05). The endogenous fluorescence intensity of tryptophan was largest at a Mg2+ concentration of 0.04 mol/L. Sodium dodecyl sulfate-polyacrylamide gel electrophoresis (SDS-PAGE) showed that the band intensity of myosin and relevant light chain proteins increased. Rheological analysis showed that the storage modulus (G’) first increased and then decreased. Compared with the control group, MP gel strength increased by 70.49% at a 0.03 mol/L Mg2+ concentration. Gel cooking loss and water-holding capacity (WHC) were negatively correlated with Mg2+ concentration (P < 0.05). Low-field nuclear magnetic resonance (NMR) analysis showed that with increasing Mg2+ concentration, immobilized water in the MP gel was transformed into free water. Microstructure observed by scanning electron microscopy (SEM) showed that the higher the concentration of Mg2+, the more porous the gel. Correlation analysis showed that Mg2+ concentration was highly correlated with the structure and gel characteristics of MP. Therefore, Mg2+ can significantly improve the gel properties of mutton MP.

ObjectiveTo investigate the etiological features and traceability of a food poisoning incident in Pudong District， Shanghai， and to provide a basis for the future investigation and disposal of similar incidents.MethodsAnal swabs of the patients and a chef and food residues were collected for pathogens isolation and identification. Enterotoxin detection immunosorbent assay （ELISA）， drug sensitivity test， pulsed field gel electrophoresis （PFGE） and multilocus sequence typing （MLST） were used for genotyping and tracing.ResultsNine anal swabs from patients， one anal swab from the chef， and 3 food residues were positive for Staphylococcus aureus （S. aureus）. Ten isolates from patients and the chef carried Staphylococcus enterotoxin （SE） A and SEE， while 3 isolates from food carried SEA， SED and SEE. All the isolates were resistant to penicillin. The S. aureus strains from the case shared the same PFGE pattern and the MLST type of them belonged to ST6.ConclusionThe cause of this food poisoning outbreak was S. aureus contamination. It is necessary to further strengthen the education and management of food processing enterprises， canteens， etc. to prevent similar incidents.

Background The prevalence of obstructive sleep apnea hypopnea syndrome (OSAHS) is high. The development of telemedicine and mobile applications play an important role in the diagnosis and screening of OSAHS patients. Objective To evaluate the value of smartphone snoring analysis software Mianyun Sara in screening of Chinese adults with OSAHS. Methods One hundred and thirty patients〔mean age (49.7±17.4) years old, 70% male and 30% female, mean body mass index (28.2±5.0) kg/m2〕who were admitted to the Sleep Center of Peking University People's Hospital from April to December 2020 were selected and underwent overnight monitoring with Mianyun Sara and polysomnography (PSG) simultaneously. The relevant indicators generated by Mianyun Sara's automatic analysis and the relevant indicators interpreted by sleep professional technicians according to the recommended guidelines, the agreement between the apnea hypopnea index (AHI) derived from this method and PSG were evaluated, as well as the sensitivity and specificity of the diagnosis of OSAHS. Results (1) The total sleep time (TST) monitored by Mianyun Sara was 523.67 (497.50, 542.64) min, and the TST monitored by PSG was 408.25 (364.25, 462.50) min, the difference was statistically significant (Z=-9.540, P8.34 times/h, with a corresponding sensitivity of 83.81% and a specificity of 92.00%. The area under the curve (AUC) was 0.91 (0.84, 0.95) , the positive predictive value (PPV) was 97.8%, and the negative predictive value (NPV) was 57.5%, at different AHI thresholds (5, 15, 30 times/h) , the sensitivity/specificity corresponding to the best diagnostic value were 83.8%/92.0%, 88.2%/74.1% and 64.9%/91.4%, respectively. Conclusion Mianyun Sara has a good screening value for adult OSAHS patients and there is close agreement between Mianyun Sara and PSG.

The quality of bauxite resources in China is deteriorating, and the high-grade bauxite resources are depleting day by day, the resource problem has become an important problem for the development of China's aluminum industry, and the high sulfur and high iron bauxite, which has not yet been exploded on an industrial scale, belongs to the difficult-to-use resources, and it has a huge potential industrial value, and it is of great theoretical and practical significance to carry out the basic research on desulfurization and removal of iron from high sulfur and high Hon bauxite. For the comprehensive development and utilization of high sulfur and high iron bauxite in Guangxi, a systematic test of desulfurization and Hon removal from bauxite was carried out by using the process of "suspension oxidation roasting-reduction roasting-magnetic separation", and the transformation of mineral phases in the roasting process was studied by using the methods of X-ray diffraction analysis (XRD), chemical phase analysis, and X-ray photoelectron spectroscopy (XPS), etc. The test was carried out on the basis of "suspension oxidation roasting-reduction roasting-magnetic separation" . The results showed that the main sulfur containing and iron-containing mineral is pyrite, the process of "suspension oxidation roasting-reduction roasting-magnetic separation" can simultaneously realize the efficient removal of sulfur and the enrichment and separation of Hon. Under the conditions of suspension oxidation roasting with roasting temperature 700 °C, roasting time 40 min, O2 concentration 40%, and the total gas volume 600 mL/min, an oxidized roasting product with S, of 0.396% and desulfurization rate of 98.10% can be obtained. Suspension reduction roasting was then carried out under the conditions of roasting temperature 550 °C, roasting time 20 min, CO concentration 20%, total gas volume 600 mL/min, and magnetic Held strength 150 kA/m, which resulted in an iron ore concentrate with TFe grade of 54.79% and aluminum-rich ore with St of 0.248%, TFe grade of 4.37% and Al2O3 content of 75.27%. This technology substantially increases the Al2O3 content of high sulfur high iron bauxite, which is conductive to the subsequent dissolution of bauxite and achieves the technical goal of desulfurization and removal of iron to raise aluminum content. This process provides a new technical way for the efficient utilization of this kind of difficult--to-process to select high sulfur high iron bauxite resources. [ABSTRACT FROM AUTHOR]

In view of the adjustment of national environmental protection policy, the Ministry of Environmental Protection and other three ministries and commissions have designated "cyanidation takings produced in beneficiation using cyanide" as hazardous waste, and the new environmental protection tax law to be implemented will levy an environmental protection tax of 1 000 Yuan/t on hazardous waste. Economic digestion of cyanide waste is the main research topic and development detection of cyanidation plants in the future. Some cyanidation tailings in Shandong province contain lead, zinc and copper of certain grade. If the cyanidation tailings are not recycled, it will not only waste resources, but also pollute the environment. If this part of polymetals is recovered, good economic benefits will be produced. Recovery of valuable metal elements from cyanidation takings is different from that from raw ore, and it is difficult to recover valuable elements from cyanidation takings. In order to solve this problem, according to the properties of the takings, representative samples are taken, and a reasonable beneficiation process is proposed to recover the valuable metals in the takings. A preferential flotation process of floating lead and zinc first and then floating sulfur is adopted, which can achieve better recovery of valuable metals. The results show that under the conditions of 2.56 = Pb, 0.95=Zn and 0.19=Cu in the raw ore, a Pb-Zn concentrate wkh Pb grade 19.77%, Pb recovery 21.50%, Zn grade 19.69%, Zn recovery 71.07% and Cu content 1.43%, and a sulfur concentrate with sulfur grade 45.27% and sulfur recovery 35.92% can be obtained by adopting the flotation process of one roughing, two cleanings and two scavengings. The new process has better process indexes, lower reagent cost and simper process. Not only lead and zinc in lead-zinc concentrate are effectively recovered, but also the associated sulfur recover is improved, which provides a scheme for the recovery of lead, zinc, copper and sulfur in cyanidation tailings. [ABSTRACT FROM AUTHOR]

Cyanidation tailings were industrial hazardous solid waste generated in the process of gold mining industry that the global annual production could reach hundreds of millions of tons. Due to the cyanide gold extraction process, the cyanide content in the cyanidation tailings was seriously excessive, which was easy to cause serious casualties if not handled properly. Therefore, it is necessary to research the harmless disposal of cyanidation tailings in order to make is subsequent resource utilization. Based on the thermal treatment method, the process mineralogy of cyanidation tailings in Inner Mongota was investigated, the cyanidation tailings were qualitively analyzed by time of light secondary mass spectrometry (TOF-SIMS) wkh high accuracy. The approach of oxidative degradation of total cyanide and thiocyanate in cyanidation tailings simultaneously by roasting was developed. The results showed that, the total cyanide content was 778.20 mg/kg, the thiocyanate content was 1 229. 41 mg/kg. When the cyanidation tailings were roasted at 550 °C for 30 minutes, at 20= O2 concentration and 600 mL/min of total gas, the total cyanide content was 1.59 mg/kg, the thiocyanate content was below the detection limit, which means the removal rate of total cyanide after treatment achieved 99.80%, and the removal rate of thiocyanate achieved 99.99%. The gas product of cyanide tailings was analyzed. The oxidation reaction of pyrite, decomposition reaction of carbonates, and continuous oxidation decomposition reactions of total cyanide and thiocyanate were described. This process filled the gap of current simultaneous treatment technology of cyanide and thiocyanate in cyanidation tailings, and efficiently oxidize and decompose high content thiocyanate while removing complex cyanide with high stability, provided theoretical support for the deep detoxification treatment of cyanidation tailings. [ABSTRACT FROM AUTHOR]

Aluminum is an important metal material in people's modern life, and bauxite is the main raw material for the production of aluminum. With the continuous development of domestic aluminum industry, the demand for bauxite resources is increasing year by year. However, the quality of domestic bauxite resources is poor, the supply is insufficient, and the degree of external dependence of bauxite is high, which brings a serious threat to the supply security of aluminum resources in China and restricts the sustainable development of China's aluminum industry. In order to cope with the scarcity of high-quality bauxite resources in China, the development of complex and difficult-to-process bauxite resources, such as high sulfur and high iron bauxite, is crucial to ensuring the strategic security of China's bauxite resources. China has a large amount of complex bauxite resources, such as high-sulfur and high-iron bauxite, which is more than 1.5 billion tons, accompanied by other strategic metal resources, which is urgently needed to be efficiently developed and advanced technology is used to realize the industrial application of this kind of typical poor and miscellaneous bauxite. Excessive sulfur and iron impurities in bauxite will have non-negligible effects on the process of aluminum extraction by Bayer process, such as corroding equipment and pipes, increasing alkali consumption and red mud, affecting the quality of alumina and so on. Therefore, starting with the present situation and characteristics of high-sulfur and high-iron bauxite resources in China, the current research progress of desulphurization and iron removal process of high-sulfur and high-iron bauxite has been summarized. The main desulfurization technologies such as flotation desulfurization, perorating desulfurization, biological desulfurization and physical iron removal, chemical iron removal and biological iron removal are summarized. The industrial application level of various processes is discussed and several typical examples of industrial application of high-sulfur and high-iron bauxite are given. It will provide theoretical support for the development and utilization of complex bauxite resources in China, make effective use of difficult-to-process aluminum resources, reduce China's dependence on foreign aluminum resources, and improve the supporting force of bauxite resources. [ABSTRACT FROM AUTHOR]

Objective To analyze the relevant risk factors for intracranial infection after craniotomy for resection of skull base neoplasms. Methods The clinical data of 159 patients with skull base neoplasms who underwent craniotomy from May 2010 to January 2020 in The Second Affiliated Hospital of Anhui Medical University were analyzed retrospectively. The relevant risk factors for intracranial infection were analyzed by univariate and multivariate forward Logistic regression. Results Postoperative intracranial infection occurred in 81 out of 159 patients, the infection rate was 50.94%. Multivariate forward Logistic regression analysis showed the operation time was ≥ 5 h (OR = 3.438, 95%CI: 1.371-8.625; P = 0.008), blood loss ≥ 400 ml (OR = 2.308, 95%CI: 1.115-4.777; P = 0.024), frontal sinus or mastoid air chamber breach (OR = 16.817, 95%CI: 3.689-76.658; P = 0.000) were the risk factors for intracranial infection after craniotomy for resection of skull base neoplasms. Conclusions There was a higher risk of intracranial infection after craniotomy for resection of skull base neoplasms in patients who had long operation time, more intraoperative blood loss as well as frontal sinus or mastoid air chamber breach. It is necessary to adopt effective prevention and control measures to reduce the risk of intracranial infection.

Uniaxial tensile tests of ethylene-chloro-tri-fluoro-ethylene (ECTFE) foils were conducted at a thickness of 250 μm and various low and high temperatures (-50, -40, -30, -20, -10, 0, 10, 20, 30, 40, 50, 60, 70, and 80 ℃). The specimens were fabricated according to the machine direction (MD). The tensile stress-strain curves of the foils at various temperatures were obtained. According to the variation discipline with temperature, several parameters such as elastic modulus, yield stress, yield strain, cold drawing stress, tensile strength, and tensile strain at break were subsequently analyzed and calculated. The results show that with the elevation of the stress-strain curves, the yield strength, tensile strength, cold drawing stress, and elastic modulus increase, but the strain at break and toughness decrease when the temperature decreases. At a wide range of temperatures from -50 ℃ to 80 ℃, the difference of elastic modulus can increase up to 93%, with a yield stress of 89%, which reflects the great sensitivity of ECTFE to temperatures. The fitting formulas of main mechanical parameters are also obtained, which can be used to predict the mechanical properties of ECTFE foils at various temperatures.

Objective To investigate the effect of nicotinate-curcumin(NC) on the LPS-induced secretion of cytokines by human umbilical vein endothelial cell (HUVECs) and its mechanism. Methods HUVECs were incubated with different concentrations of NC for 24 h. Western blot was used to detect the phosphorylation of AMPK. After silencing the expression of AMPK with siRNA, the potential outcomes on the phosphorylation of NF-kappa B p65, the expression of adhesion molecules, the secretion of TNF-alpha and MCP-1 in the supernatant of LPS-induced cells, and the expression of endoplasmic reticulum stress markers IRE-1, eIF2α and CHOP were observed. Results The phosphorylation of AMPK was significantly increased and p65 phosphorylation was alleviated after HUVECs treatment with the concentration of 10~20 mmol/L NC for 24 h (P＜0.05). After silencing of AMPK, the inhibition effect of NC on NF-κB was significantly reduced(P＜0.05). At the same time, the expressions of ICAM-1, VCAM-1 and E-selectin, and the adhesion of THP-1 cells to HUVECs, content of TNF-α and MCP-1 in supernatants were significantly reduced after NC treatment (P＜0.05). After siRNA silenced AMPK, the above effects were all inhibited(P＜0.05). NC down-regulated the expression of endoplasmic reticulum stress markers IRE-1, eIF2α and CHOP induced by LPS. The inhibitory effect of curcumin on these molecules was significantly reduced by interfering with the expression of AMPK (P＜0.05). Conclusions NC inhibits LPS-induced expression, secretion of adhesion molecules and cytokines in HUVECs, and also inhibits endoplasmic reticulum stress. The mechanism is potentially related to the activation of AMPK.

With the rapid development of industry and agriculture, organic pollutants in aqueous solution has caused serious influence for ecological environment. Zeolite have the advantages of large surface area, good stability and strong cation exchange ability. Therefore, it is widely used in adsorption of pollutants in aqueous solution. Quaternary ammonium cationic surfactant is often used as a modifier for zeolite because it has high surface activity, easy to adhere to the zeolite surfaces and change surface electrical properties of zeolite. The structural properties of zeolite, the quaternary ammonium cationic surfactant interaction with zeolite and modified zeolite interaction with adsorbent are reviewed. Research progress on the adsorption of drugs, heavy metal ions, water-soluble dyes, ammonia nitrogen and phenolic compounds by quaternary ammonium cationic surfactant modified zeolite is also introduced. It puts forward some problems and possible development directions in the use of modified zeolite in water pollution removal. It provides theoretical guidance for the practical application of modified zeolite environmental protection. [ABSTRACT FROM AUTHOR]

The aim of the experiment was to explore the mechanism of Qizhi oral liquid in enhancing the immune function of poultry. The active ingredients and their targets of Astragalus and Ganoderma lucidum in the compound were collected by the traditional Chinese medicine systematic pharmacology database and analysis platform (TCMSP), and the immune targets were collected by the OMIM, TTD and GeneCards databases. The potential target of Qizhi oral liquid for the poultry immunity was obtained. The Chinese medicine-component-target-pathway-disease network diagram and protein interaction (PPI) network were constructed by Cytoscape 3.9.1 software, and GO enrichment and KEGG pathway analysis were performed on the targets. The molecular docking of active ingredients and core targets was verified by molecular docking technology. The results showed that the .30 components of Qizhi oral liquid correspond to 66 targets, and .329 targets of poultry immunization, including 17 intersection targets. The core PPI targets included nuclear factor κB inhibitor α (NFKBIA), interleukin-6 (IL-6) and interferon γ (IFNG). There were .38 results of GO functional enrichment, including .3.3 biological process items, four molecular function items and one cell component item. KEGG pathway analysis showed that the intersection genes were mainly concentrated in the C-type lectin receptor signaling pathway, the FoxO signaling pathway and the toll-like receptor signaling pathway. The results of molecular docking showed that the key components had good binding activity with the core protein target, which proved the reliability of the prediction results of network pharmacology. The study indicates that Qizhi oral liquid can enhance the immune function of poultry through a multi-component, multi-target and multi-pathway. [ABSTRACT FROM AUTHOR]

To explore the efficacy of Xuebijing injection in the treatment of emergency patients with severe sepsis and its impact on coagulation function. Methods Seventy-eight patients with severe sepsis were randomly divided into the control group (n = 39) and the Xuebijing group (n = 39) by the random number table method. All patients in both groups were treated with routine anti-sepsis bundle therapy according to the 2016 International Guidelines for the Treatment of Sepsis and Septic Shock. In addition to these routine treatments, the Xuebijing group was treated with a Xuebijing injection, while the control group was given an equal amount of sodium chloride. The platelet count (PLT), coagulation function, thromboelastography (TEG) values, acute physiology and chronic health evaluation II (APACHE II) score, the stay time at the emergency intensive care unit, and the fatality rate within 28 days were compared between these two groups before and after 7 days of treatment. Results After 7 days of treatment, the PLT count in the Xuebijing group increased significantly, and the fibrin/fibrinogen degradation products (FDP) decreased significantly (P < 0.05); the PLT count in the control group continued to decrease (P < 0.01). After 7 days of treatment, FDP and D-Dimer (DD) in the Xuebijing group were lower than those in the control group (P < 0.01), and clot formation time was significantly shortened; α angle, maximum clot strength (MA), and coagulation index (CI) were significantly increased, and all were better than those in the control group (P < 0.05). There was no statistically significant difference in these indicators before and after treatment in the control group (P > 0.05). After 7 days of treatment, APACH II scores in both groups decreased compared to before treatment (P < 0.05), but the performance of the Xuebijing group was better (P < 0.05). The 28-day fatality rate in the Xuebijing group was 17.95%, lower than that in the control group at 23.08%. Conclusions Combined with routine symptomatic treatment, Xuebijing injection could effectively improve the coagulation function of sepsis patients, showing a positive role in the treatment of sepsis patients. [ABSTRACT FROM AUTHOR]

Influence of fabric electrode on polyvinylidene fluoride (PVDF) piezoelectric film property was studied. Sheet resistance of 3. 5 Ω·cm² silver paste screen printing polyester fabric was prepared by screen printing method. Silver-plated polyester fabric and copper screen fabric with same sheet resistance were selected. Three kinds of fabric were used as electrode together with PVDF piezoelectric film to encapsulate and prepare flexible piezoelectric sensor. Dielectric contact property, sensitivity and durability of the three fabric piezoelectric sensors were tested. The test results showed electrode dielectric impedance of silver-plated fabric and copper screen fabric were stable when the frequency was lower than 4 kHz. When the frequency was around 1x104 Hz, the fluctuation of relative dielectric constant for silver paste screen printing fabric electrode was obvious. It was obviously higher than those of the other two fabric electrodes under high frequency condition. The dielectric property of silver-plated fabric electrode was close to that of copper screen fabric electrode. The three kinds of electrode all had a certain piezoelectric susceptibility. The sensitivities of silver paste screen printing fabric electrode and copper screen fabric electrode were slightly higher. After 2 000 times of pressing, sawtooth square signals still could be output for silver-plated fabric electrode and copper screen fabric electrode. Obvious baseline drift phenomenon was appeared for silver paste screen printing fabric electrode. It is considered that the overall properties of flexible piezoelectric sensor packaged by copper screen fabric as electrode are better. Dielectric property and durability of silver-plated fabric are better. Sensitivity of silver paste screen printing fabric is better. The three kinds of fabric can be used as electrode material to produce sensor. However, problems like motion artifact and so on need to be further studied. [ABSTRACT FROM AUTHOR]

In the traditional artificial potential field method, the local minimum point problem exists in path planning, which makes the mobile robot unable to move to the target point. Therefore, an artificial potential field method based on simulated annealing algorithm is proposed. Artificial potential field method uses the simulated annealing algorithm to add random target points near the local minimum point and guide the mobile robot to escape from the local minimum point area gradually. Finally, Matlab simulation proves that the method can make the mobile robot escape from the local minimum position, successfully reach the target position, consumes shorter time, and is more stable. [ABSTRACT FROM AUTHOR]

A travertine is a special chemical or biochemical deposition. They are widely distributed in the interior of the continent and contain important geological information and are special reservoirs of oil and gas. The factors that affect the deposition of travertines are complex and diverse. Based on the investigation of the formation process and classification of travertines, this article discusses the controlling factors of travertine formation from five aspects : climate environment, hydrogeological conditions, physical and chemical conditions of water bodies, biological activities, and structural activities. Then, the travertine in the Tabei area of Xinjiang province is compared with foreign travertine deposits in terms of depositional environment, model, and deposition rate. The travertine deposits show good seasonal stratification under a warm and humid environment in north Tarim. The travertine in Wudaopan area was deposited into a large amount of terrigenous debris and greatly affected by biological activities. In Liuhuanggou, travertines are a product of hydrothermal upwellings resulting from fault activity. By comparing and summarizing the findings, the travertine that filled in the fractured caves in Tabei has well-developed internal pores, good connectivity, and good oil content display. Therefore, the travertine has a certain storage capacity. [ABSTRACT FROM AUTHOR]

The important agronomic traits, such as grain type, plant height, and panicle composition, are closely related to rice yield, and their gene inheritance is complex. Chromosome segment substitution lines (CSSLs) are useful materials for studying these complex traits. An excellent CSSL, Z746, containing seven substitution segments and with an average substitution length of 3.99 Mb, was identified from Nipponbare as a recipient and 'Xihui 18' as a donor parent. There were significant differences in plant height, panicle composition and grain size between Z746 and Nipponbare. Furthermore, a total of 36 quantitative trait loci (QTL) were detected on chromosomes 2, 3, 4, 6, and 11 in the secondary F2 population constructed by hybridization between Nipponbare and Z746. Five of them may be alleles of the cloned genes, such as qPH3-1, and eight can be detected by multiple times, indicating that these were genetically stable major QTLs. The grain length in Z746 was mainly controlled by four QTLs (qGL3, qGL4, qGL2, and qGL6), and the phenotypic variation of qGL3 and qGL4 for grain length was 60.28% and 27.47%, respectively. Plant height was controlled by five QTLs, panicle length by four QTLs, grain number per panicle by two QTLs, and the 1000-grain weight by two QTLs. Eight single segment substitution lines (SSSLs) were developed in F3 population by molecular marker-assisted selection (MAS), and relevant QTLs verification was conducted in F4. Finally, 24 QTLs were detected by 8 SSSLs and the repeat detection rate was 66.7%, indicating that these QTLs were genetically stable. These results provide a good foundation for further research on genetic mechanisms of the target QTLs and molecular design breeding. [ABSTRACT FROM AUTHOR]

Taking a tailings pond project in Yunnan as a research background, address to the dally variation of the stability of the takings dam, three-dimensional numerical simulation, the analysis of the infiltration line of the dam-filling model test, and the indoor permeability coefficient test are used. The experimental results of the takings body permeability coefficient and the empirical values of the permeability coefficients calculated with reference to the seepage flow of the tailings dam at home and abroad, considering the ansotropy of the tailings body in the tailings dam, select reasonable calculation parameters, the differences between the tailings reservoir burial depth and variation law of infiltration line of tailings dam under working conditions are analized. The research shows that the test results are in good agreement with the three-dimensional numerical simulation calculation results and can reflect the real situation. [ABSTRACT FROM AUTHOR]

To develop functional materials with high retention ability for hydrogen cyanide (HCN) and crotonaldehyde in cigarette smoke, 20 tetrabutyl ammonium hydroxide-amino acid ionic liquids (TBAILs) were prepared. The structures of TBAILs were characterized, and their toxicant-reducing performance in smoke was evaluated. The effects and stability of TBAILs on reducing the releases of HCN and crotonaldehyde in mainstream cigarette smoke were evaluated in the form of paper-cellulose acetate dual composite filter. The results showed that: 1) The structures of TBAILs were confirmed by Fourier transform infrared spectroscopy (FTIR) and nuclear magnetic resonance spectroscopy. In addition, thermogravimetric analysis indicated that TBAILs had good thermal stability under 150 °C . 2) The adsorption performance tested on a bespoke device revealed that all of the 20 TBAILs had substantial reductions for HCN (>80% ), wherein 13 TBAILs also showed a high efficiency for crotonaldehyde (>60% ). 3) When tetrabutyl ammonium-threonine ionic liquid ([N4444][Thr]) was applied to cigarette filters at 10 mg/cig., compared with the control cigarettes, the releases of HCN and crotonaldehyde in mainstream smoke were reduced by 50.8% and 27.7%, respectively, and the smoke sensory quality did not change obviously. The toxicant-reducing performance of [N4444] [Thr] was maintained after storing for 3 months. [ABSTRACT FROM AUTHOR]

Glioma is the most common primary tumor of central nervous system (CNS), about 50% of which is extremely malignant glioblastoma (GBM). GBM is the most common primary malignant brain tumors in adults. Surgery, radiotherapy and chemotherapy (most with temozolomide) are regarded as the conventional treatments, but they failed to significantly prolong the survival of GBM patients. The standard treatment of GBM lacks of specificity, and tumor cells are resistant to radiotherapy or alkylating agents, thus recurrence of GBM is inevitably and the overall prognosis is quite poor. Currently, tumor immunotherapy is emerging and booming, which provides more treating options for GBM. This study, hence, reviews the current status of immunotherapy among the comprehensive treatments of glioma, at the same time indicates the potential targets of immunotherapy, further to update treatment strategies and explain the potential for the resistance of immunotherapy. [ABSTRACT FROM AUTHOR]

At present, AI has risen to become the core strategy for the transformation and upgrading of science and technology in various countries. Under the background of the internet of everything, all walks of life have set off a research boom of AI. The telecom industry is no exception. As the carrier network faces the challenge of digital transformation, the automatic driving of the telecommunication network through AI technology has gradually become the consensus of the industry. Huawei's SoftCOM AI solution for autopilot and its deployment methods, values and cases were introduced . [ABSTRACT FROM AUTHOR]

In this study, investigation on plant community was conducted in Heyeping subalpine meadow of Luya Mountain in Shanxi Province of China. The importance values of 36 herbaceous species, α diversity index, phylogenetic diversity index, as well as their correlations were investigated. The results showed that the species diversity of the subalpine meadow was uniformly distributed. Species richness was higher in marginal areas, indicating an 'edge effect'. The phylogenetic structure of four plots was convergent and that of 12 plots was dispersive. The phylogenetic diversity index (PD) was positively correlated with the Petrick index, Simpson index and Shannon index, while there was no significant correlation of either the net relatedness index (NRI) or the nearest taxon index (NTI) to the α diversity indices. [ABSTRACT FROM AUTHOR]

This paper explains concepts of virtual reality and 3D stereoscopic projection technology, discusses the construction of software and hardware for the virtual laboratory in the College of Landscape and Architecture, Nanjing Forestry University. It provides reference materials for the laboratory building of the same type. [ABSTRACT FROM AUTHOR]

Circulation among industries is an important feature of an economy and an essential structural factor to form its industry competitiveness in the internet age. Based on industry networks, we studied cycle degree of an industry and its connotation which describe this feature. Cycle degree of an industry is the number of cycles crossing the industry, depicting multi-direction circular linkages and reflecting the eflFect of the industry on circulation. Industries with big cycle degrees can influence more industry cycles, and become the core of industrial cyclic operation. In view of the studies on the properties of circle degree of an industry, we designed an algorithm to calculate it. Exemplification indicates that cycle degree of an industry can describe its importance quantitatively from the perspective of industry circulation, and reflect the similarities and differences of industry structures. This suggests that as a kind of structural indicator, cycle degree of an industry is of great theoretical and practical significance for further researching on industrial cluster, the upgrading of the industrial structure, industrial competitiveness, etc. [ABSTRACT FROM AUTHOR]

Rotating packed beds can efficiently intensify the gas-liquid mass transfer process. As one of the key design parameters, the mass transfer efficiency is hard to predict accurately due to the complex factors including structural parameters (rotor dimensions, packing characteristics, etc.) and operating parameters (rotational speed, gas and liquid flowrates, gas and liquid concentrations and operating temperature, etc.). In this work, dimensionless variables that affect the mass transfer coefficients for CO2 absorption into NaOH solutions with rotating packed beds were introduced. Therefore, a model based on least squares support vector machine (LS-SVM) for prediction of gas-liquid mass transfer performance of CO2 absorption by NaOH solutions in rotating packed beds was proposed. Optimal model parameters of γ = 3.833 4x104, δ² = 0.7176 were obtained by grid search method based on simulated annealing combined with 10-fold cross-validation method. The validity of the model was demonstrated by prediction of 57 sets of data. The model predictions are in agreement with experimental data within ±15% ;mean square error is 4.01x10-5 and correlation coefficients (R²) is 0.9842. The present model shows a good accuracy and generalization. [ABSTRACT FROM AUTHOR]

Our analysis of resolutions adopted by international congresses of penal law in the last hundred years shows that the resolutions have firmly adhered to the fundamental standpoints of the rules of law and the protection of human rights, and have also made efforts to realize justice in the area of the rules of criminal law judgment from their attitudes to security measures and to concern bland causes. Moreover, the resolutions had followed the principle of responding to realistic needs, emphasizing the basic criminal theories and facilitating combination of criminal substantive and procedural law. The resolutions have also brought forward with pertinent suggestions that are in accordance with the aforementioned principles while remaining flexible and stable but active in such areas as environmental crime, economic crime, corporate crime, terrorism crime, and high-tech crime. [ABSTRACT FROM AUTHOR]

A method of how to uniformly distribute the accuracy on the azimuth direction of the optic-electronic system and mast platform system is put forward. This method is used to distribute and analyze the accuracy of the mast-mounted photodetection system. The overall accuracy index is separately distributed to photodetection system and mast platform system. This accuracy distribution is calculated based on the system parameters to prove whether it could satisfy the accuracy requirement. The rationality of accuracy distribution approach of the mast-mounted photodetection system is validated through infield experiment. The calculated and experiment error values of azimuth direction of the photodetection system are 1. 2" and 1. 9", respectively, which are less than 2". The calculated and experiment error values of azimuth direction of the mast platform system are 19. 7"and 23. 5", which are less than 24". The overall calculated and experiment error values of the system are less than 25". [ABSTRACT FROM AUTHOR]

To investigate the displacement wave propagating characteristics of the flexible floating bridge that is subjected to high-speed and heavy load, the dynamic equation of the floating bridge is presented and solved by means of superposition method and the theory of beam on elastic foundation is employed. The displacement wave propagation velocities, the ratio of the maximum wave amplitude to the maximum displacement of floating bridge and the time history of the slope at the load place with respect to load velocity are gained. The numerical results show that the displacement wave will propagate towards both sides of the floating bridge subjected to high-speed and heavy load. New phenomena including the displacement wave accumulation and load climbing-slopes will occur when the velocity of moving load is faster than that of propagation of the displacement wave. And these phenomena will be more visible when the velocity of load is higher. [ABSTRACT FROM AUTHOR]

By using amplified fragment length polymorphism (AFLP) technique, an investigation was made on the genetic diversity and genetic differentiation of seven wild populations of Rhododendron concinnum in Qinling Mountains of Northwest China.A total of 182 amplification products were generated from three AFLP selective primer combinations, of which, 151 were polymorphic.The percentage of polymorphism was 83.1%. The change trends showed by the percentage of polymorphic loci (PPL), Nei's gene diversity (h), and Shannon's information index (I) were uniform, and the order of the populations was Meixian > Zhashui > Zhen'an > Huxian > Ningqiang > Nanzheng > Zhouzhi. The POPGENE analysis showed that the R.concinnum had higher genetic diversity at both species level (PPL=91.22%,I=0.7217,h=0.5095) and population level (PPL=77.56%,I=0.6409,h=0.4725). The coefficient of gene differentiation among the populations (Gst) was 0.0726, indicating that 92.74% of genetic variation occurred within the populations. The analysis of molecular variance (AMOVA) showed that 85.3% of the genetic variation was within the populations, and 14.7% of it was among the populations. The unweighted pair group method with rithmeticmean (UPGMA) indicated that there was no significant correlation between the genetic distance and the geographic distance among the R. concinnum populations. The conservation strategies for R. concinnum germplasm resources were put forward. [ABSTRACT FROM AUTHOR]

To explore an effective measure to ensure the safety of rice quality in cadmium (Cd)-contaminated farmland, a pot culture experiment was conducted to study the effects of of low Cd content (Cd<0. 2 mg∙kg-1 ) phosphorous fertilizers with an application rate of 0. 10 or 0. 20 g P2O5∙kg-1 on the phytoavailability of Cd in its contaminated paddy soil, with the related mechanisms discussed. Compared with no phosphorous fertilization, applying 0. 10 P2O5∙kg-1 of calcium magnesium phosphate (CMP) and monopotassium phosphate (MKP) increased soil pH and decreased soil available Cd content significantly, and CMP and calcium superphosphate (CSP) decreased the Cd accumulation in rice significantly. When the application rate was up to 0. 20 g P2O5∙kg-1, calcium hydrogen phosphate (CHP) increased the soil pH and decreased the soil available Cd content significantly, and CMP, MKP, and CHP decreased the DTPA-extractable soil Cd content by 11. 8%, 9. 8%, and 11. 8%, and the NH4 OAc-extractable soil Cd content by 9.5%, 7.1%, and 7.1%, respectively. All test phosphorous fertilizers could significantly decrease the stem and leaf Cd contents, with a decrement of 24. 9% -50. 8%, and except CHP, the others could significantly decrease the Cd content of brown rice. With the application CMP and CSP, the Cd content of brown rice was close to the National Hygienic Standard for Grains (GB 2715 -2005). Among the test phosphorous fertilizers, those can increase soil pH (CMP, MKP, and CHP) could significantly decrease the availability of soil Cd significantly, and those containing calcium (CMP and CSP) were more effective in decreasing the Cd accumulation in rice. The efficiency of the phosphorous fertilizers was mainly determined by their chemical properties. Alkaline calcium-containing phosphorous fertilizers were more effective in decreasing the Cd absorption and accumulation in rice plant in Cd-contaminated farmland. [ABSTRACT FROM AUTHOR]

In a long term sitespecific experiment with rice straw return (RSR) and in a short term experiment with different RSR modes, this paper studied the effects of RSR on the soil organic car bon (SOC) sequestration, methane emission, and net carbon sink in a double season paddy field. RSR increased the SOC content, and the annual increasing rate of soil carbon sink in plow layer (0-15 cm) under long term RSR was 0.07 t C · hm-2 · a-1. With the increasing amount of RSR, the apparent SOC transformation rate decreased. RSR promoted the methane emission from the pad dy field significantly, and the methane emission flux in treatment RSR plus NPK during earlyand late rice growth seasons increased by 75. 0% and 251. 5% (P <0. 01), respectively, compared with that in treatment NPK. The methane emission increased with the increasing amount of RSR. Under the similar tillage mode and rice yield, the rice straw returned had the similar apparent methane transformation rate. Considering the soil carbon sequestration and the net carbon sink after methane emission in the paddy field comprehensively, treatment RSR plus NPK had significant negative effect on the carbon sink which was basically approached to the biofixation of carbon by rice and increased by 158.3%, as compared with treatment NPK. Among different RSR modes, rice straw mulching plus no tillage decreased soil methane emission significantly, with the net carbon sink decreased by 50. 9% as compared with the treatment high stubble plus tillage, and benefited the high and stable yielding of rice. [ABSTRACT FROM AUTHOR]