Search

Objective To study the effect of implanted stent or selected operation in patients with acute occlusion of right coronary artery during the emergency coronary arteriongraphy. Methods Forty-three patients with acute occlusion of right coronary artery who underwent the emergency coronary arteriongraphy were divided into two groups: the implanted stent group (n = 23) during the emergency coronary arteriongraphy and the selected operation group (n = 20) during the emergency coronary arteriongraphy. Then we observed the general data, the coronary artery pathological changes, preoperative and postoperative thrombus, the blood flow, remained stenosis and the prognosis. Results The implanted stent group was similar to the control group in general condition, but implanted stent group was significantly different from the control group in the near, intermediate and distal coronary artery pathological changes (P < 0.05). The control group was significantly different from the implanted stent group in the thrombus and slowly blood flow (P < 0.05). After three months, we reviewed coronary arteriongraphy and selected operation. The implanted stent group was significantly different from the control in the remained stenosis and slowly blood flow (P < 0.05). But the implanted stent group was similar to the control group in the thrombus and new proceeding cardiovascular events. Conclusion When thrombus appears in acute occlusion of right coronary artery, we can implant stent during the emergency coronary arteriongraphy if the thrombus is little, or we can select operation after PTCA on the contrary. [ABSTRACT FROM AUTHOR]

Objective To evaluate the clinical efficacy and safety of bosentan and sildenafil in the treatment of the severe pulmonary artery hypertension with congenital heart disease. Methods All patients with severe pulmonary hypertension as well as congenital heart disease in our hospital from January 2009 to February 2012 were selected as the object, and ten patients were enrolled, of which, 3 cases were male, 7 cases were female, the average age was 43.04±19.74 years old. They were all treated with bosentan and sildenafil for 6 months. The main end points were WHO classifications of pulmonary hypertension, and the second end points were hemodynamic indexes such as pulmonary artery pressure. Results After treatment for 6 months, there were significant improvements in the main end points including WHO classifications of pulmonary hypertension; there improvements of the second end points such as pulmonary artery pressure and cardiac output; and then there were notable improvement of physical properties for instance red blood cell and uric acid; difference of which had statistical significance. But there were no significant changes in aminotransferase and three tricuspid regurgitation velocity of other physical properties than those of before treatment. No severe side effects and complications were observed. Conclusion The results reveald the efficacy and safety of oral administration of combining bosentan and sildenafil in the severe pulmonary artery hypertension with congenital heart disease. [ABSTRACT FROM AUTHOR]

Objective To study the relationship of arrhythmias and heart electrical parameters changes after transcatheter closure of ventricular septal defect (VSD). Method 50 patients had been successfully finished the transcatheter closure of ventricular septal defect, and then we observed relationship of arrhythmias and heart electrical parameters changes. Results (1) Compared with the situation of VSD occluder preoperative and postoperative, during follow-up there were 20 arrhythmia cases, including bundle branch block 16 cases, including the complete left bundle branch block 2 cases, complete right bundle branch block 4 cases, a transient third-degree trioventricular conduction block 1 case, most return to normal in the follow-up. 2 Intracavitary electrogram showed before and after transcatheter closure: A-V conduction parameters A-H, H-V value of (75.10 ± 14.34) ms vs (80.67 ±23.03) ms and (47.9 ± 12.61) ms vs (50.07 ± 15.23) ms, the difference was not statistically significant (P>0.05). Conclusions (1) Some patients with new ECG changes after transcatheter closure of VSD, manifested as an increase in bundle branch block in a week, but most return to normal, the prognosis is good. (2) Intraoperative A-H, H-V extension is not related with with postoperative slow arrhythmia; (3) Arrhythmia is a common complication after VSD transcatheter closure, to strictly selected indications, and to avoid too large diameter are the effective measures to reduce the arrhythmias after transcatheter closure of ventricular septal defect (VSD). [ABSTRACT FROM AUTHOR]

Objective To discusses the efficacy and safety of patent ductus arteriosus sealing for low body weight children. Methods From January 2008 to June 2012 in our hospital, 32 cases (male 14 and female 18) of PDA babies < 8 kg weight were given transcatheter closure treatment. The enrolled PDA babies aged 6 month-18 months, average (11 ± 5.5 months), weighted (7.2 ± 0.6) kg, aortic imaging showed the narrowest diameter of PDA was 1 ~ 8 mm (4.6 ± 1.7) mm, descending aorta imaging was performed immediately and 30 min after transcatheter closure treatment. Echocardiography and X-ray radiography examination were performed 1d, 1, 3, 6 months after treatment. Results 30 cases got successful patent ductus arteriosus sealing, all the successful patients were treated with domestic closer, and 1 case was complicated with the descending aorta stenosis and ventricular septal defect, and was transferred to surgerical treatment. 1 case of PDA gave up patent ductus arteriosus sealing as descending aorta stenosis caused by the closer. 2 cases were found a trace-residual shunt immediately after patent ductus arteriosus sealing. No serious complications were found in all patients during the follow-up period. Conclusions Application of domestic closer in treatment of PDA infants < 8 kg is a safe, effective and simple intervention treatment method with little trauma and fast recovery. [ABSTRACT FROM AUTHOR]