Search

The sources and trends of antibiotics and heavy metals in the environment, the current pollution status of their combined pollution and the research progress of their ecological effects were reviewed. Antibiotics and heavy metals coexist in the environment with high probability, which have been detected simultaneously in water and soils environment in many areas of China. The main pathways of combined pollution of them were the returning field of manure and sewage and waste water treatment plant. The combined pollution of antibiotics and heavy metals has the ecotoxicological effects on plants, animals and microorganisms, and the degree of the ecotoxicological effect of the combined pollution is related to the types and concentrations of pollutants, biological species and exposure times. Water environment is one of the main sites of combined pollution by antibiotics and heavy metals. There are few studies on the effects of combined pollution of them on aquatic organisms, which need to be further explored. The in-depth and comprehensive toxicological analysis should be conducted from the cellular and molecular levels to study the biotoxicological effects of combined pollution of them. [ABSTRACT FROM AUTHOR]