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COVID-19 pandemic has provoked a huge change in daily functioning in millions of people worldwide. The epidemiological measures in prevention of possible infection have increased the possible risks on the mental and physical health. We have conducted a survey in order to investigate the needs and challenges of families with children with chronic respiratory diseases. In this order, we have created a questionnaire with general information about the family, general information about the child with chronic respiratory disease, overall physical and mental health before and during the pandemic, needs and mental health condition of the parents/caregivers. This survey showed that this group of families of children with respiratory disorders have suffered financially in significant way and has changed the way they perform professional and educational patterns due to the pandemic. Most of the children were stable in their physical health, but their mental health has deteriorated. This is probably due to the regular contact with the medical staff, but not with the mental health professionals. This group of children has a significant reduction in their physical activity and increase the hours in front of TV screens. The further effect on the physical and mental health is to be investigated. [ABSTRACT FROM AUTHOR]

To understand the etiological detection and epidemiological regularity of respiratory viruses in children with respiratory tract infections, so as to provide etiological basis for the prevention, diagnosis and treatment of respiratory tract infections in children. 280 children with respiratory tract infections who were admitted to General Hospital of Central Theater Command of PLA from January 2016 to December 2017 were selected as the study subjects. The detection of respiratory viruses in children with respiratory tract secretions were analyzed, and the relationship between respiratory viral infection and age, season and disease type in children with respiratory tract infection were analyzed. 98 positive specimens were detected in 280 children with respiratory tract infection, the positive rate was 35.00%. 2 viruses were detected in 2 samples, and the positive rate of mixed infection was 0.71%. Among all virus types, the respiratory syncytial virus (RSV) had the highest positive rate. The highest positive rate of viral infection was found in children younger than 1 year old, which was significantly different from that in other age groups (P<0.05). The positive rate of respiratory tract infection in spring and winter was significantly higher than that in summer and autumn (P<0.05). The positive rates of viral infection in children with different respiratory tract infections were significantly different (P<0.05). The positive rate of virus infection in children with asthmatic pneumonia, bronchiolitis and pneumonia was higher. RSV is the main pathogen of respiratory viral infection in children with respiratory tract infection. Infants younger than 1 year old are more susceptible to infection. Spring and winter are the high incidence seasons. The positive rates of virus infection in children with pneumonia, bronchiolitis and asthmatic pneumonia are higher. [ABSTRACT FROM AUTHOR]

Objective To study TCM patterns and mechanism for pediatric pneumonia with the approach of symptom correlation analysis. Methods 480 cases records of pediatric pneumonia were collected from multiple centers as a large sample data source. Correlation analysis was conducted to analyze both the to-tal dataset and subgroups by patterns under the guidance of TCM theory and clinical practice so as to study TCM patterns and mechanism for pediatric pneumonia. Results More than 30 000 association rules were mined from the total samples, from which the basic pathogenesis of pediatric pneumonia was confirmed to be heat, stagnation and phiegm. And over 100 000 association rules were obtained from the subgroups. Heat pattern is the primary underlying one. Compared with the pattern of wind heat invading lung, the support and confidence of the pathogenesis related to heat were higher than the pattern of phlegm-heat obstructing lung, while those of the pathogenesis related to stagnation, to phlegm, were low-er than the pattern of phlegm-heat. Conclusion The approach of symptom correlation analysis could be used for a more standard, objective, and scientific TCM development as it is consistent with the spirit of evidence based practice. [ABSTRACT FROM AUTHOR]