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Copyright of Chinese Journal of Applied Mechanics is the property of Chinese Journal of Applied Mechanics Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

AIM: To investigate whether Panax notoginseng saponins (PNS) attenuate arecoline (ANE)-induced human oral submucous fibrosis (OSF) by regulating ferroptosis, and to study its mechanism. METHODS: The OSF model was established by treating human immortalized keratinocyte cell line HaCaT with ANE. There were 6 groups created: blank group, model group(50 mg/L ANE), low-, medium- and high-dose (12. 5, 25 and 50 mg/L)PNS groups, and liproxstatin-1 (ferroptosis inhibitor) group. The morphological changes of the cells were observed under a light microscope. Cell viabilty was detected by CCK-8 assay. Collagen type I (Col-l), solute carrier family 7 member 11(SLC7A11) and glutathione peroxidase 4(GPX4)protein expression levels were detected by Western blot. The morphological changes of mitochondria were observed by transmission electron microscopy. The Fe2+ level was detected by FerroOrange fluorescent probe. The intracellular reactive oxygen species (ROS) content was detected by DCFH-DA fluorescent probe. The content of glutathione (GSH)was determined by colorimetry. RESULTS: Compared with blank group, the majority of the cells in model group displayed long spindle shape, fibrotic appearance, unstable adhesion, and obvious morphological changes. Under electron microscope, mitochondrial double membrane density increased, and cristae decreased significantly, presenting typical ferroptosis. The expression of Col-I increased, GPX4 and SLC7A11 protein expression decreased, Fe2+ and ROS levels increased, and GSH content decreased (all/><0. 05). Compared with model group, most of the cells in low-, medium- and high-dose PNS groups were round and epit he lo id, with decreased mitochondrial membrane density, increased ridge number and normal morphology, decreased Col-I expression and ROS level, and increased GSH content (all P<0. 05). Compared with model group, the protein expression levels of GPX4 and SLC7A11 in medium- and high-dose PNS groups were significantly increased, while the content of Fe2+ was significantly decreased (all P<0. 05). There were no significant differences in cell and mitochondrial morphology and indicator levels between liproxstatin-1 group and high-dose PNS group (all 05). CONCLUSION: Panax notoginseng saponins can alleviate OSF by preventing the ferroptosis of HaCaT cells induced by ANE. [ABSTRACT FROM AUTHOR]

Objective To investigate changes of serum Angptl2 and Angptl4 levels in patients with polycystic ovary syndrome (PCOS) and their relationship with ovarian interstitial hemodynamics. Methods A total of 123 PCOS patients (the PCOS group) and 41 healthy volunteers (the control group) were selected. The serum Angptl2 and Angptl4 levels, the peak systolic velocity (PSV), pulsation index (PI) and resistance index (RI) of ovarian interstitial were compared between the two groups. The relationship between Angptl2, Angptl4, PSV, PI, RI and PCOS and their predictive value to PCOS were analyzed. Results The PI and RI values of left and right ovarian interstitial were lower in the PCOS group than those in the control group, and PSV values were higher than those in the control group (P＜0.05). Pearson analysis showed that serum Angptl2 and Angptl4 were positively correlated with PSV of left and right ovarian interstitial, and negatively correlated with PI and RI of left and right ovarian interstitial in patients with PCOS (P＜0.01). Logistic regression results showed that high HOMA-IR (OR=1.921, 95%CI: 1.017-4.154), high BMI (OR=1.459, 95%CI: 1.085-3.220), high Angptl2 (OR=2.625, 95%CI: 1.330-6.324), high Angptl4 (OR=3.543, 95%CI: 1.915-8.147) levels were related factors affecting the occurrence of PCOS (P＜0.05). Receiver operating characteristic curve (ROC) showed that the AUC (95%CI) of predicted PCOS were 0.747 (0.661-0.821) and 0.769 (0.685-0.841) when serum Angptl2 and Angptl4 were used alone. It was lower than that of 0.879 (0.793-0.921, P＜0.05) for the combined application. Conclusion The abnormal levels of serum Angptl2 and Angptl4 in PCOS patients are related to the hemodynamics of ovarian interstitial, and they are closely related to the occurrence of PCOS, which can be used as reference indexes for the evaluation of PCOS. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Previous studies have shown that a single change in the expression of a gene or the state of a cell in the area of spinal cord injury has no significant effect on functional recovery after spinal cord injury. An increasing number of evidence shows that the regulation of cellular microenvironment after spinal cord injury is a key factor hindering the recovery of neurological function. OBJECTIVE: To review the biological characteristics of cellular microenvironment before and after spinal cord injury, including the effect and mechanism of mutual regulation among different kinds of cells and extracellular components on nerve repair after spinal cord injury. METHODS: The first author retrieved the databases including PubMed and Web of Science for articles published from January 2000 to December 2021 using the key words of “spinal cord injury, glial cell, neuron, immune cell, neural stem cell, extracellular matrix, cytokine, extracellular vesicle, regeneration”. Finally, 64 articles were selected for analysis. RESULTS AND CONCLUSION: (1) After spinal cord injury, among the cellular components of the cellular microenvironment, the interaction among glial cells, which account for the highest proportion, and the interaction with neurons are particularly critical. (2) Among the extracellular components after spinal cord injury, the hydrogels with good biocompatibility used to imitate natural extracellular matrix can effectively simulate and reconstruct the cellular microenvironment in the injured area and promote axonal elongation. (3) Among the extracellular regulatory factors after spinal cord injury, proinflammatory factors such as tumor necrosis factor-α and interleukin-1β aggravate the inflammatory storm of cellular microenvironment. Using receptor inhibitors or blocking related pathways to down-regulate the expression of adverse extracellular regulatory factors is an effective therapeutic method in the cellular microenvironment. At the same time, there are also studies on increasing the expression of anti-inflammatory factors such as interleukin-10 in the microenvironment of the spinal cord and on inhibiting the development of inflammation in the injured area. (4) Recently, extracellular vesicles have also played an important role in the cellular microenvironment as carriers of information. (5) This article reveals multiple sets of mutual regulatory relationships between cellular components and extracellular components in the cellular microenvironment after spinal cord injury, emphasizing that the neuroreparative effects of various components in the cellular microenvironment are not isolated. [ABSTRACT FROM AUTHOR]

Copyright of Electric Power is the property of Electric Power Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Southeast University / Dongnan Daxue Xuebao is the property of Journal of Southeast University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

提出了整数值随机游走过程，推导出该随机游走过程的若干和式的极限分布.证明了无截距、无时间趋势的单位根过程的自回归系数的最小二乘估计量的极限分布不再是Weiner过程的泛函，而是依概率收敛到真值1，最后还用Monte Carlo模拟验证了该结论的合理性.

Copyright of Forest Research is the property of Forest Research Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Irrigation & Drainage is the property of Journal of Irrigation & Drainage Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Kunming Medical University / Kunming Yike Daxue Xuebao is the property of Kunming Medical Journal and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Northeast Petroleum University is the property of Journal of Northeast Petroleum University Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The CCS Hydropower Station in Ecuador is characterized by the axis of the diversion to power generation system up to 2 800 m long, the internal and external heads more than 600m, the large groundwater recharge, the developed steeply dipping broken zone and the densely caves criss-crossly arranged, all of these result in gushing water problems during construction and many key and difficult points in waterproof-drainage design. According to the sensitivity analysis of internal water leakage based on seepage field's analysis over various conditions by FLAC 3D, multi-factor instability analysis for wedges considering joints' and fractures' water pressure coupling of in-situ stress by 3DEC, combining with the high-pressure permeability characteristics analysis based on high water pressure tests results, features analysis of the safety monitoring data at the characteristic times after the water-filling test until recently, the research on key technologies for waterproof-drainage and also certification for control measures were finally put forward. Using water-permeable lining, combining with geomembrane, consolidation grouting, curtain grouting for the upstream high-head water diversion system, drainage hole curtain based on drainage gallery and system drainage holes for the downstream power generation system and so on, after all these permanent and temporary combination measures, the power station currently is running well, the safety monitoring data are not anomaly and have been converged for a long time, which certifies the rationality of the waterproof-drainage design for diversion to power generation system under the high internal and external water condition. [ABSTRACT FROM AUTHOR]

Copyright of Petroleum Refinery Engineering is the property of Petroleum Refinery Engineering Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The paper discussed classification limitation and computational complexity of categorization algorithm based on sparse representation, and proposed a novel weighted locally linear KNN algorithm for text categorization, which used weighted function to make the representation coefficients sparse, and introduced nonnegative constraints to improve the classification performances. Moreover, this paper gave the parameters experiments to select the optimization value, and gave the theoretical proof of the algorithm. The experiments show the superiority of the algorithm based on weighted locally linear KNN, which has an average improvement on 2. 49% and 0. 85% in precision and recall, compared with the traditional mcxlel. It means the text categorization algorithm based on weighted locally linear KNN has advantages of high classification accuracy and strong convergence, which is suitable for high-dimensional data classification. [ABSTRACT FROM AUTHOR]

BACKGROUND: The human leukocyte antigen (HLA) has undergone long-term evolution to form diverse polymorphisms. In recent years, due to the increase in the number of examinees and the rapid development of HLA typing technology, novel HLA alleles have been discovered constantly. OBJECTIVE: To analyze the full-length sequence and 18 point mutations of HLA-B gene in a leukemia patient and her family using the next-generation sequencing technology. METHODS: Polymerase chain reaction and sequence-specific oligonucleotide probes (PCR-SSOP) and polymerase chain reaction-sequence based typing (PCR-SBT) revealed abnormalities in the patient’s HLA-B. To identify the genotype, we sequenced the full length of the gene by next-generation sequencing technology and collected blood samples from the patient’s father, mother and two sisters for genetic analysis of HLA genes. RESULTS AND CONCLUSION: Both PCR-SSOP and PCR-SBT indicated that the HLA-B sample had no perfectly matched genotype. Further detection using the next-generation sequencing technology revealed that the novel allele had 18 base mutations in the exon, intron and 3'UTR compared to the most homologous allele B*15:09:01. Five exon base mutations were located in the exons 3 and 4, which were: 486G→C, 583T→C, 636T→C, 652A→G, 756C→T, resulting in changes in the five corresponding codons, including 171 tyrosine (Tyr) → histidine (His) and 194 isoleucine (Ile) → valine (Val). A pedigree survey found that the patient’s novel HLA B allele was inherited from her father. The novel allele sequence was submitted to the Genbank database (MG595995). A novel HLA-B allele was confirmed by the next-generation sequencing, which was officially named HLA-B*15:435 by the World Health Organization HLA Factor Nomenclature Committee in December 2017. [ABSTRACT FROM AUTHOR]

The area of CCS Hydropower Station tailrace channel belongs to high earthquake degree area, where the geological condition is poor, overburden is deep, the elevation of bedrock surface varies greatly and the tailrace channel is very closely to the only major road of the power station, directly leading to the limitation of excavation range of tailrace channel and forming a stability issue for high and steep slope condition. This project included multiple difficult points and complex conditions, which was a typical case of slope design. In order to make sure safety, “multiple parameter truth value inversion analysis” was adopted to obtain geological parameter, designer put forward the combined supporting design idea of ground wall, pre-stress cable, top beam anti-slide pile, pre-stress rock bolt and grout bolt. This project guaranteed the road safety and avoided the delayed construction period by other road plan. At present, the power station is running well, the safety monitoring data are not anomaly and have been converged for a long time, which certifies the rationality of design idea and support plan for tailrace channel slope. [ABSTRACT FROM AUTHOR]

The underground powerhouse system of CCS hydropower station in Ecuador is characterized by large-span caverns and three directions short distance in space, which brings about complicated three directions thin pillar problems. The joints development and strike unfavorable in the caverns area, it is easy to form unstable wedge. Based on the European and American codes, using domestic and foreign engineering analogy method, two-dimensional and three-dimensional analysis methods, and based on the “NATM”, the design ideas of integrally using shotcrete with wire mesh and bolts, partially considering shotcrete with steel set and bolts for supporting, and the design concept of partial reinforcement for wedges on the basis of integral system support were finally put forward. This project had avoided the delayed construction period by large-scale pre-stressed anchors and cables. At present, the power station is running well, the safety monitoring data are not anomaly and have been converged for a long time, which certifies the rationality of the support structures for underground caverns. [ABSTRACT FROM AUTHOR]

Copyright of Journal of Beijing University of Technology is the property of Journal of Beijing University of Technology, Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To investigate the effect of "U" suture hemostasis on the amount of bleeding in cesarean section of placenta previa patients. Methods: 96 cases of patients undergoing placenta previa cesarean section maternal admitted from September 2015 to September 2017 in our hospital were selected as the research materials and randomly assigned to two groups, with 48 cases in two groups. Both groups of patients were given the routine hemostatic treatment, the control group was given "8" suture hemostasis, the observation group was given "U" suture hemostasis, the index and hemostatic effect were compared between two groups. Results: The operation time, hemostasis time, and intraoperative blood loss of observation group were all significantly less(shorter) than those of the control group(P<0.05), the thrombin time(TT), plasma thrombin reduction time(PT), D-dimer(DD), platelet(PLT), and activated partial clotting activase time(APTT) were significantly lower than those of the control group(P<0.05), the levels of hemoglobin(HGB) and fibrinogen(FIB) were significantly higher than those of the control group(P<0.05), the effective rate of hemostasis[97.92%(47/48)] was significantly higher than that in the control group[(85.42%(41/48)](P<0.05), the time of ambulation and hospitalization were significantly shorter than those of the control group(P <0.05). Conclusion: Implementation of "U" suture hemostasis has the advantages of simple operation in the rapid hemostasis of placenta previa cesarean section, it could reduce the amount of bleeding and ensure maternal health with high safety. [ABSTRACT FROM AUTHOR]

Copyright of Yellow River is the property of Editorial Board of Yellow River and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

For the embedded water stop, the position conflicts between the waterstop and the rebar appear frequently in design and construction. For the back attached waterstop, the exposure outside can cause harm for the durability. In order to solve the inadaptability, according to the structural characteristics and the working principles of those two kinds of waterstops, the side attached waterstop was initially proposed and firstly used in Lanzhou Water Source Project with good adaptability. The side attached waterstop has provided convenient both for the design and construction. [ABSTRACT FROM AUTHOR]

Objective To study the influence of tarsal gland massage on postoperative curative effect of femtosecond laser combined with excimer laser keratomileusis. Methods A prospective study was conducted on patients who underwent the same surgical approach by the same surgeon. 78 eligible patients were randomly divided into two groups: 39 patients in experimental group, equal to 78 eyes, were given tarsal gland massage before the operation; and the other 39 patients in control group, equal to 78 eyes, were not given tarsal gland massage before the operation. The presence condition of postoperative interlayer eyelid fat of the two groups of patients was investigated. After that, the patients were divided into two groups according to above eyelid fat condition: with eyelid fat group and without eyelid fat group, and the visual acuity recovery status were compared between the two groups.Results In the control group after the operation, 3 patients could not be contacted in the follow-up study, but a total of 36 patients, equal to 72 eyes were observed by slit lamp, and there were totally 10 eyes with interlayer eyelid fat, accounting for 13.89%; Whereas, 2 patients could not be contacted in the experimental group, but a total of 37 patients, equal to 74 eyes were observed, and there were only 2 eyes with interlayer eyelid fat,accounting for 2.7%. The P value of comparison between these two groups was less than 0.01, which had statistical differences. There was significant difference between the two groups(P <0.05) in the recovery of visual acuity within one month after the operation. Conclusion Tarsal gland massage can effectively reduce the residual of interlayer eyelid fat after the operation of femtosecond laser combined with excimer laser keratomileusis, thereby it can avoid the delay of vision recovery and effectively improve the postoperative curative effect. [ABSTRACT FROM AUTHOR]

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Tissue Engineering Research / Zhongguo Zuzhi Gongcheng Yanjiu is the property of Chinese Journal of Tissue Engineering Research and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Beijing Normal University is the property of Beijing Normal University, Institute of History and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

目的探讨系统性红斑狼疮(SLE)患者血清血小板反应蛋白1(TSP-1)水平变化及临床意义。方法选择SLE患者97例作为观察组(活动期53例、缓解期44例)、体检健康志愿者50例作为对照组。用酶联免疫吸附法检测两组血清TSP-1水平,并检测血红蛋白、白细胞、血小板、尿素氮、血肌酐、24 h尿蛋白、补体C3、补体C4、抗ds DNA抗体水平。用Pearson相关分析SLE患者血清TSP-1水平与其他指标的相关性。结果观察组血清TSP-1水平高于对照组(P <0. 05),而血红蛋白、白细胞、血小板、补体C3、补体C4水平低于对照组(P均<0. 05),活动期SLE患者血清TSP-1水平较缓解期高(P <0. 05)。合并口腔溃疡、皮疹、脱发、关节炎、狼疮性肾炎、溶血性贫血、白细胞减少、血小板减少、低补体C4和低补体C3的SLE患者血清TSP-1水平高于未合并患者(P均<0. 05)。SLE患者血清TSP-1水平与血红蛋白、白细胞、血小板、补体C3和补体C4水平呈负相关(r分别为-0. 725、-0. 697、-0. 716、-0. 731、-0. 709,P均<0. 05),与抗ds DNA抗体水平呈正相关(r=0. 752,P <0. 05),而与尿素氮、血肌酐、24 h尿蛋白无相关性(r分别为0. 235、0. 347、0. 193,P均> 0. 05)。结论 SLE患者血清TSPS-1水平升高,其水平越高患者病情越严重,并发症越多。 [ABSTRACT FROM AUTHOR]

Copyright of Journal of Modern Laboratory Medicine is the property of Journal of Modern Laboratory Medicine Editorial Department and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Objective: To compare the efficacy of domperidone and low-dose Erythromycin in the treatment of feeding intolerance in very low birth weight infant （VLBWI）Methods: A retrospective analysis was performed on 90 cases of VLBWI with feeding intolerance who admitted in our hospital from January 2011 to December 2013. According to the choice of therapy, the patients were divided into group A (domperidone group, n=42) and group B (low-dose erythromycin group, n=48). On the basis of comprehensive treatment the children of different groups were treated with different drugs as mentioned above the feeding intolerance symptoms.then the subside time of feeding intolerance symptoms, time to regain birth weight, the incidence of total parenteral feeding time, duration of hospitalization and incidence of side effects were observe and compared between two groups. Results: After treatment，all the children in both groups，achieved feeding intolerance symptoms, regained birth weight, total parenteral nutrition in the discharge standards. No statistically significant difference was found in the time of indicators mentioned above between two groups (P>0.05). No related adverse reactions was adversed in group A，while six cases of local pain caused by intravenous erythromycin was adversed in group B，the incidence rate was 12.5%, it was significantly higher than that of group A (P <0.05). Conclusion: Both domperidone and low-dose intravenous erythromycin could be effective and equal in the treatment of feeding intolerance in VLBWI. But domperidone might have higher security. [ABSTRACT FROM AUTHOR]