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Shunbei fault-karst reservoir in Tarim Basin is a special type of carbonate reservoirs. The reservoir spaces are mainly formed by caves and fractures transformed by faulting. Due to reservoir spaces with complex structures， irregular shapes， and strong randomness of distribution， there are many uncertainties in the traditional delineation technology of fracture-cavity spaces based on static seismic data. The forward simulation method of numerical well testing is adopted to analyze the geological significance of different well test curves according to fracture-cavity space delineation results， and it is clear that the fault-karst reservoirs can be dynamically characterized based on well test analysis. A quantitative characterization method of reservoir spaces is proposed by correcting the threshold values of fracture-cavity delineation with dynamical numerical well test data. This method determines the shapes and reserve sizes of the reservoir spaces， and then selects a more accurate delineation models by combining well test interpretation， production characteristics analysis， and other research means and using the reservoir space knowledge with the dynamic correction to constrain the threshold values of the seismic attributes.

Timely detection and treatment of tomato diseases can effectively improve the quality and yield of tomato. In order to realize the real-time and non-destructive detection of tomato diseases, a tomato leaf disease classification and recognition method based on improved MobileNetV3 was proposed in this study. Firstly, the lightweight convolutional neural network MobileNetV3 was used for transfer learning on the image net data set. The network was initialized according to the weight of the pre training model, so as to realize the transfer and fine adjustment of large-scale shared parameters of the model. The training method of transfer learning could effectively alleviate the problem of model over fitting caused by insufficient data, realized the accurate classification of tomato leaf diseases in a small number of samples, and saved the time cost of network training. Under the same experimental conditions, compared with the three standard deep convolution network models of VGG16, ResNet50 and Inception-V3, the results showed that the overall performance of MobileNetV3 was the best. Next, the impact of the change of loss function and the change of data amplification mode on the identification of tomato leaf diseases were observed by using MobileNetV3 convolution network. For the test of loss value, focal loss and cross entropy function were used for comparison, and for the test of data enhancement, conventional data amplification and mixup hybrid enhancement were used for comparison. After testing, using Mixup enhancement method under focal loss function could improve the recognition accuracy of the model, and the average test recognition accuracy of 10 types of tomato diseases under Mixup hybrid enhancement and focal loss function was 94.68%. On the basis of transfer learning, continue to improve the performance of MobileNetV3 model, the dilated convolution convolution with expansion rate of 2 and 4 was introduced into convolution layer, 1×1 full connection layer after deep convolution of 5×5 was connected to form a perceptron structure in convolution layer, and GLU gating mechanism activation function was used to train the best tomato disease recognition model. The average test recognition accuracy was as high as 98.25%, the data scale of the model was 43.57 MB, and the average detection time of a single tomato disease image was only 0.27s, after ten fold cross validation, the recognition accuracy of the model was 98.25%, and the test results were stable and reliable. The experiment showed that this study could significantly improve the detection efficiency of tomato diseases and reduce the time cost of disease image detection.

Corn is one of the most important food crops in China, and the occurrence of disease will result in serious yield reduction. Therefore, the diagnosis and treatment of corn disease is an important link in corn production. Under the background of big data, massive image data are generated. The traditional image recognition method has a low accuracy in identifying corn plant diseases, which is far from meeting the needs. With the development of artificial intelligence and deep learning, convolutional neural network, as a common algorithm in deep learning, is widely used to deal with machine vision problems. It can automatically identify and extract image features. However, in image classification, CNN still has problems such as small sample size, high sample similarity and long training convergence time. CNN has the limitations of expression ability and lack of feedback mechanism, and data enhancement and transfer learning can solve the corresponding problems. Therefore, this research proposed an optimization algorithm for corn plant disease recognition based on the convolution neural network recognition model combining data enhancement and transfer learning. Firstly, the algorithm preprocessed the data through the data enhancement method to expand the data set, so as to improve the generalization and accuracy of the model. Then, the CNN model based on transfer learning was constructed. The Inception V3 model was adopted through transfer learning to extract the image characteristics of the disease while keeping the parameters unchanged. In this way, the training process of the convolutional neural network was accelerated and the over-fitting degree of the network was reduced. The extracted image features were used as input of the CNN to train the network, and finally the recognition results were obtained. Finally, the model was applied to the pictures of corn diseases collected from the farmland to accurately identify five kinds of corn diseases. Identification test results showed that using data to enhance the CNN optimization algorithm and the migration study on the average recognition accuracy main diseases of com (spot, southern leaf blight, gray leaf spot, smut, gall smut) reached 96.6%, which compared with single CNN, has greatly improved the precision and identification precision by 25.6% on average. The average processing time of each image was 0.28 s, shortens nearly 10 times than a single convolution neural network. The experimental results show that the algorithm is more accurate and faster than the traditional CNN, which provides a new method for identification of corn plant diseases.

Using the bottom slag of domestic waste incinerator as the aggregate of dry concrete can solve the problem of disposal of bottom slag of domestic waste incinerator to a certain extent. In this paper, the effects of MSW incinerator bottom slag on the mechanical properties and drying shrinkage of dry hard concrete are studied through Weibull consistency test, cylinder compression test and drying shrinkage test, and the mechanism of this effect is analyzed. The experimental results show that domestic waste incineration slag is feasible as fine aggregate of dry hard concrete. When the content of bottom slag is higher than 30%, the water consumption increases sharply. Adding 30% bottom slag reduces the 28d strength of dry hard concrete by 22.1%, and the drying shrinkage values at 7d, 14d and 28d are reduced by 2.24%, 8.73% and 9.04% respectively. This is mainly due to the high water absorption of the bottom slag of MSW incinerator and the alkali silica gel produced in the dry concrete due to the incorporation of bottom slag. [ABSTRACT FROM AUTHOR]

Objective: To explore the molecular basis for an individual with ABO subtype., Methods: The ABO phenotype of the proband was determined by convention serological testing. Exons 6 and 7 of the ABO gene were subjected to PCR amplification and bi-directional Sanger sequencing. Haplotypes for exons 6 and 7 of the proband was determined using an ABO haplotype-specific amplification and sequencing technique., Results: Red blood cells of the proband showed a 4+ agglutination strength with anti-A or anti-H, no agglutination reaction with anti-A1, and a 3+ agglutination strength with anti-B. His serum had no reaction with standard A cells, O cells or self cells, but was weakly reactive with B cells at 4℃. The proband was assigned as an ABO subtype based on his serological features. Bi-directional sequencing of the ABO gene revealed heterozygosity of 261 G/del, 297AG, 526CG, 657CT, 703GA, 803GC and 930GA, and homozygosity of 796CC in the proband. Haplotype-specific amplification and sequencing showed that one of his alleles was ABO*O.01.01, and another contained a c.796A>C variation compared with the ABO*B.01 allele, which led to replacement of methionine by leucine at position 266. Searching the ABO allele database of International Society of Blood Transfusion suggested the variation to be a novel one., Conclusion: The c.796A>C variation in the ABO*B.01 allele probably underlies the CisAB subtype. Accurate identification of the ABO subtype requires combined use of serological method and genetic testing.

Objective: To evaluate the association between high sensitivity C-reactive protein (hsCRP) and breast cancer incidence among the non-diabetic females in a large-scale cohort study in Kailuan group., Methods: The Kailuan cohort was established on May 1, 2006. Baseline information on demography, lifestyle, medical history, and anthropometry, i.e., body height and weight, were collected during the baseline interview, and breast cancer incidence, mortality and other related outcome information were obtained by follow-up every two years and the related health condition database information were collected every year. Multivariable Cox proportional-hazards regression model was used to calculate the hazard ratios (HRs) and 95%CI (confidence interval) between the level of hsCRP at baseline interview and breast cancer incidence adjusted for age group, body mass index (BMI), marital status (married and single) and tobacco smoking (smokers and non-smokers) when appropriate., Results: By Dec 31, 2011, a total of 17 402 females were enrolled in the cohort. There were 85 286 person-years of follow-up with a mean follow-up period of (58.81 ± 4.52) months. A total of 75 incident breast cancer cases were collected. Subjects with the highest level (>3 mg/L) of hsCRP at baseline interview were associated with a significantly increased risk of breast cancer (adjusted HR = 1.80, 95%CI = 1.03-3.15) compared with those with the lowest level (<1 mg/L)., Conclusions: Elevated levels of hsCRP at baseline interview may be associated with an increased risk of breast cancer among non-diabetic females. Further follow-up and etiological exploration will help to evaluate the association between the hsCRP level and the risk of breast cancer more reliably.