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Cardiovascular disease represents the leading cause of death in the world, and early diagnosis and treatment are critical to its prognosis. The lncRNA-taurine up-regulated gene 1 (TUG1) mediates a competing endogenous RNA network involved in the development of cardiovascular diseases, involving biological processes such as inflammation, immunity, apoptosis, pyroptosis and oxidative stress. This review summarizes the progress of lncRNA-TUG1 as a competing endogenous RNA to mediate the above biological processes in coronary atherosclerotic heart disease, myocardial ischemia-reperfusion injury, heart failure, hypertension, atrial fibrillation and diabetic cardiomyopathy, to provide a reference for subsequent research on cardiovascular diseases. [ABSTRACT FROM AUTHOR]

The PI3K/Akt/mTOR signaling pathway are closely related to the regulation of cell growth, which can be a pivotal part that participates in production and development of bovine adipocytes, bovine mammary epithelial cells and bovine oocytes, can also be a participant, indirectly regulating inflammatory factors, metabolic processes, et al. The paper reviews the components, mechanism and effect on growth of different cells of PI3K/Akt/mTOR signal pathway, to provide reference for the follow-up study on how livestock cell growth. [ABSTRACT FROM AUTHOR]

Due to the openness and diversity of the Internet, different platforms provide different quality information, and the descriptions of the same object can be conflict with each other. Truth discovery is one of the important technical means to resolve semantic conflicts and improve the data quality. Traditional truth discovery methods usually assume that the relationship between source reliability and claim credibility can be represented by a simple function. These methods design iterative rules or probability models to find trustworthy claims and sources. However, manually-defined factors are often difficult to reflect the real underlying distribution of the data, resulting in an unsatisfied truth discovery result. In order to solve this problem, a truth discovery method based on neural network encoding is proposed. Firstly, the method constructs a double-loss deep neural network which contains "source-source" and "source-claim" relationships. Secondly, it embeds the sources and claim into a low-dimensional space, which indicates the source reliability and claim credibility. Based on the optimization, the reliable sources and the trustworthy claims are close in the embedding space (meanwhile, unreliable sources and untrustworthy claims). Finally, truth discovery is performed based on the embedding space. Compared with traditional methods, it is not necessary for the proposed method to manually define the iterative rules or data distribution before truth discovery. The method utilizes the neural network to automatically learn the complex relationships among sources and claims, and then embeds them into a low-dimensional space. The experimental results on the real dataset show that the proposed model increases the precision by 2%-25% in comparison to the iterative based methods such as Accu, by 2%-4% in comparison to the probabilistic graphical model based methods such as 3-Estimate, by 2%~5% in comparison to the optimization based method such as CRH, and by 1%~2% in comparison to the neural network based method FFMN. [ABSTRACT FROM AUTHOR]