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Geological phenomena of volcanism and metallogenesis indicate that boron can be transported significantly in aqueous fluids and gases. In this study, the Ion Selective Electrode Method was used to determine the solubility of boron in hydrothermal vapor in order to determine the ability of gaseous transport of boron. The electric potentials of boric acid standard solutions and boron-bearing condensates of water vapor after conversion to tetrafluoroborate ion with hydrofluoric acid were determined using a fluoroborate selective electrode. When the concentrations of boron change within the main range of geological fluids (0.52-524.50 mg/L), the calibration curve reveals a good linear Nernstian relationship between the potential and the logarithm of boron content with high sensitivity, good stability and good reproducibility. The detection limit of this method is 0.13 mg/L of boron, within uncertainties, which is lower than the upper limit of boron content standard for potable waters. This method is suitable for boron analysis of hydrothermal vapor. The experimental results of boric acid volatilization show that boron content in water vapor reaches 0.65%-0.72% at 150℃ and 0.37 MPa, which is consistent with boron-rich volcanic fumarole gases, demonstrating that boron can be remarkably transported in vapor phase and exists mainly in gaseous molecule species H3BO3 under high-temperature hydrothermal conditions. The geological characteristics of ore deposits and available experimental evidence indicate that boron transport in vapor and subsequent tourmalinization is closely related to the mineralization of rare metal type pegmatites and the formation of hydrothermal-pneumatolytic type Sn-W and Mo deposits and porphyry Cu and Au deposits.

In order to investigate on gas production characteristics and its influencing factors of Jurassic low rank coal reservoirs in the western China, In the current study, the gas production of different surface wells, the key factors and controlling mechanisms were analyzed based on the geological information of surface boreholes and historical gas production data. 1 he results show that the reservoir properties and hydro-geological conditions are important key factors which influence on the gas productions in the Binchang Dafosi coalfield. For the selected surface wells,the horizontal multi-branches wells performs better in terms of gas production, the highest daily gas production is about 16 582. 3 m3/ d. The vertical well is the second good performer, while the U shaped well is relatively poor. The historical data of gas production show that there is an obvious exponential function relationship between the bottom pressure and gas productions. With the decrease of bottom pressure,gas production would increase following the exponential relationship. At the different period of gas production, the height of fluid surface has different effects on gas production. The influence is much more significant at high gas production periods. There is a linear relationship between the casing pressure and gas production, however, the proportion of the linear relation varies greatly at different drainage stages. Through the historical data of gas production, one exponential function relationship have been deduced from the data between the ratios of daily gas production and the accumulated gas production with drainage time. A gas production prediction model has been established and the fitting coefficients are higher than 0. 848 2,which shows a high accuracy. [ABSTRACT FROM AUTHOR]

Objective: To investigate the expression and clinical significance of soluble interleukin-2 receptor(sIL-2R) in patients with multiple myeloma(MM)., Methods: 54 newly diagnosed MM patients in the Second Affiliated Hospital of Fujian Medical University from February 2020 to December 2021 were selected as the observation group, and 60 healthy people in our hospital in the same period were selected as the control group. The expression levels of sIL-2R in the serum of the two groups were detected by enzyme-linked immunosorbent assay. The differences of sIL-2R expression level among different clinical parameter groups in MM patients were compared. The clinical parameters include:gender, age, ISS stage, hemoglobin, albumin, serum creatinine, lactate dehydrogenase and β 2 -microglobulin, blood calcium, bone marrow plasma cell ratio and treatment response. The relationship between sIL-2R expression level and progression-free survival(PFS) and overall survival(OS) in MM patients were analyzed., Results: The expression of serum SIL-2R in MM patients was significantly higher than that in healthy control group ( P <0.05). The expression of sIL-2R in MM patients who did not achieve complete remission(CR) was significantly higher than those of CR patients ( P =0.037). There was no significant difference in the expression of serum sIL-2R between the groups of different sex, age, ISS stage, hemoglobin concentration, albumin content, serum creatinine level, lactate dehydrogenase level, the content of β 2 -microglobulin, the concentration of blood calcium, and the proportion of bone marrow plasma cells( P >0.05). The PFS of sIL-2R high expression group(15 months) was shorter than that of sIL-2R low expression group (22 months), which was significant difference ( P =0.041). But there was no significant difference in OS between sIL-2R high expression group and sIL-2R low expression group ( P =0.124). Univariate analysis results showed that the high expression of serum sIL-2R was associated with poor PFS in MM patients. Multivariate analysis results showed that the high expression of serum sIL-2R was still an independent adverse prognostic factor for PFS in MM patients, However, the expression of serum sIL-2R was not statistically significant in evaluating OS in MM patients by univariate and multivariate analysis., Conclusion: The expression of serum sIL-2R in MM patients was significantly higher than that in healthy people. Serum sIL-2R is an independent prognostic factor of PFS in MM patients.

Objective: To study the influence of different concentrations of selenium on the growth and absorbing of Se,Cd,Pb,Hg and As in Trillium tschonoskii., Methods: Trillium tschonoskii was treated with different concentrations of exogenous selenium, arsenic and heavy metals,and then the mass growth, leaf area,root number and other indicators reflecting its growth rule were calculated. Atomic fluorescence method was used to measure the absorption contents of Se,Cd,Pb,Hg and As., Results: The relative mass growth,leaf area and root number of Trillium tschonoskii increased at first and then decreased with the increasing of exogenous selenium concentrations. When the concentration of selenium was 25 mg / kg,the relative mass growth,leaf area and root number of Trillium tschonoskii reached a maximum. When selenium concentrations was over than 30 mg / kg,it inhibited the growth and development of Trillium tschonoskii. Trillium tschonoskii absorbing Cd,Pb,Hg and As had a regular of first decreasing then increasing and last decreasing. It reached the lowest when selenium concentrations at the range of 10 ~ 15 mg / kg. ., Conclusion: Selenium had both stimulating effect and inhibiting effect on the growth and development of Trillium tschonoskii. Different selenium concentrations have different effects in absorbing Cd,Pb,Hg and As of Trillium tschonoskii

Far Fourier transform infrared spectroscopy (Far-FTIR) and terahertz time-domain spectroscopy (THz-TDS) were used to measure the fingerprint spectra of Azitromycin suspension, capsule, tablet and dispersible tablet under vacuum and nitrogen conditions, respectively. In the frequency range of 0.2-15 THz, highly resolved spectral features for Azitromycin suspension were measured and some minor differences were observed between domestic and exotic Azitromycin Suspension, such as linewidth broadening and additional peaks. As same time, for the domestic Azitromycin capsule, tablet and dispersible tablet, the absorption baselines in the range of 0.2-2.7 THz rise with the increase of frequency while absorption peaks become weaker due to the scattering of bigger particles and smaller amount of Azitromycin. Also, the additional peaks are caused by the absorption of filling materials. In parallel with the qualitative measurement, the THz absorption spectra for mixtures of polyethylene (PE) powders and exotic Azithomycin suspension with different concentrations were also measured. According to the linear correlation between the concentration and the absorption intensity, the concentration of effective component can be evaluated accurately. This means that THz-TDS method is suitable for the quality inspection and evaluation of the mixed Azithromycin system.

The effects of assistant side-blown operating parameters on the behavior of plasma characteristics and plasma geometry were studied with the aid of high-speed camera in laser dressing of bronze-bonded diamond grinding wheel. The results showed that: high pressure argon plasma reduces swelling height, and as the pressure increases, argon blowing side of the plasma effect is more obvious. Plasma emission spectrum was studied on the grinding wheel radial maximum value with the change in argon gas pressure through the acquisition of plasma emission spectroscopy using spectrometer, and according to the Boltzmann slash and Stark broadening method, the maximal values of plasma electron temperature and electron density in the wheel radial were calculated. It was found that the plasma spectral line intensity first increased and then decreased as gas pressure reached the peak at 0. 2 MPa, Larger argon pressure can significantly reduce the temperature and density of plasmas. With optical 3D scanner the wheel surface topography before and after adding side-blown gas was compared. The results indicated that: the topography of grinding wheel with 0. 5 MPa side-blown argon is better than that without adding side-blown gas.

This study is to investigate the impairment and possible mechanism of endothelium-dependent relaxation of mice mesenteric arteries induced by mmLDL. Wire myography was employed to examine endothelial function of mesenteric arteries. Ultramicrostructure of mesenteric vascular beds were detected by transmission electron microscope. The results showed that endothelium cell edema and peeling, vascular elastic membrane fracture traces in mmLDL group. Endothelium-dependent relaxation was decreased in a time-dependent and dose-dependent manner by using mmLDL, compared with normal arteries. In endothelium-derived hyperpolarizing factor (EDHF)-mediated relaxation, the Rmax and pIC50 were decreased from (63 +/- 5) % and 6.42 +/- 0.09 of normal saline control to (31 +/- 3) % and 5.67 +/- 0.07 in mmLDL group (P < 0.001, P < 0.001), respectively. In nitric oxide (NO)-mediated relaxation, the Rmax and pIC50 were decreased from (45 +/- 4) % and 5.93 +/- 0.08 in normal saline control to (32 +/- 4) % and 5.43 +/- 0.11 in mmLDL group (P < 0.05, P < 0.01), respectively. There is no significant alteration of prostacyclin I2 (PGI2) pathway between these two groups. In conclusion, mmLDL induced the impairment of the ultramicrostructure of mesenteric vascular endothelium cell as well as the endothelium-dependent relaxation. The latter includes the dysfunction of NO- and EDHF pathway mediated endothelium-dependent relaxation.

In the present work, five films on the surface of pure titanium were formed by microarc oxidation technique at various applied voltages: 300, 350, 400, 450 and 500 V. The phase component and microstructure of these films were analyzed by scanning electron microscopy and Raman spectroscopy. The result shows that the surface of the films is covered by numerous micropores. With the increase in applied voltage, the size of these micropores increases, but the density of these micropores declines. These films consist of anatase and rutile phases, and the phase component of the film is closely related to the applied voltage. In the condition of lower applied voltage, the film is mainly composed of anatase phase. With increasing the applied voltage, the content of rutile phase increases, and when the applied voltage ranges from 400 to 450 V, the rutilephase increases sharply and becomes domain phase.

Objective: To study the effect of luteolin on COX-2 and mPGES-1 expression in LPS-induced RAW264.7 cells., Methods: After being pretreated with different concentrations of luteolin for 30 min, and then incubated with 1 microg/ml LPS for 12h, the effect of luteolin on the product of PGE2 in RAW264.7 cells was measured by enzyme immunoassay (EIA). The mRNA expression of COX-2 and mPGES-1 in RAW264.7 cells were analysed by RT-PCR. The COX-2 and mPGES-1 protein expression in RAW264. 7 cells were analysed by western blotting., Results: Luteolin inhibited the LPS-induced PGE, synthesis in RAW264.7 cells. The mRNA and protein expression of COX-2 and mPGES-1 in RAW264.7 cells were also decreased by luteolin., Conclusion: Luteolin can inhibit significantly the expression of COX-2 and mPGES-1 in PGE2 synthetic pathway.

Through observing the responses of photosynthesis in leaves of broad bean grown under natural conditions to light and CO(2) using a portable photosynthetic analyzer LI-6400, the following findings were obtained. (1) Observing the response of photosynthesis to light using a leaf without being induced by light might lead to an artifact that photosynthesis was not saturated even under full sunlight. (2) The calculated saturating light intensity of photosynthesis by some empirical equations was much lower than actual value obtained by observing. (3) During observation of photosynthetic response to CO(2), each step of changing CO(2) concentration should be accompanied by a match step of the photosynthetic analyzer, otherwise, there will be substantial deviations in the results obtained. (4) Observing photosynthetic response to CO(2) at non-saturating light might lead to an underestimation of leaf photosynthetic capacity.

Objective: To observe the effect of pentoxifylline (PTX), albendazole (ABZ), and a combination of PTX and ABZ in mice infected with Echinococcus multilocularis (E.M)., Methods: The first part of the experiment was to observe the in vitro effect of PTX on the cultured E.M protoscolex. In the second part, mice were infected by abdominal inoculation of E.M and divided into groups given by ABZ 50 mg/kg-d, PTX 360 mg/kg-d, PTX 180mg/kgxd, and a combined regimen ABZ 50 mg/(kgxd)+PTX 180 mg/(kgxd). Another infected group and a uninfected group served as controls which received normal saline only. 100 days post-treatment, the mice were sacrificed for further observation. Indicators included wet weight of the cyst, cyst inhibition rate, level of serum cytokines TGF-beta determined by ELISA, IL-2 and IL-10 determined by radio-immunoassay (RIA)., Results: The inhibition rate on cysts of the combined ABZ and PTX was 88%, considerably higher than 58 % of the group ABZ. The serum TGF-beta and IL-10 decreased and IL-2 increased after treatment in comparison to the controls., Conclusion: The PTX and ABZ combination shows better effect on E.multilocularis infection than that of single ABZ. PTX might help increase immunity of the mice.

Objective: To evaluate the effect of the compound of Dan-shen root and azone for scar treatment., Methods: The rat skin in vitro and the human skin in vitro and vivo were separately examined their permeability of the mixture of the Dan-shen root and azone. The 301 patients with hypertrophic scar were randomly divided into two groups: one treated with elastic cloth paste (including silicone) contained in Dan-shen root with azone, and the another treated with only elastic cloth paste (including silicone)., Results: The permeability of Dan-shen root with azone, passing through the rat skin in vitro and the human skin in vitro and vivo was significantly higher than both the distilled water and the normal saline (P < 0.05). In the clinical study for treatment of the hypertrophic scars, the efficient rate of the group with the Dan-shen root with azone was significantly higher than the control (91.4% vs. 71.3%) (P < 0.01)., Conclusion: The Dan-shen root with azone could be easier to permeate the skin and more effective to treat the hypertrophic scar.