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Gallbladder adenomyomatosis(GA) is a relatively rare benign disease of unknown both etiology and pathogenesis. The development of imaging technology improved diagnosis of GA. Some believed that GA related to gallbladder cancer, which is still controversial. Preventive cholecystectomy was proposed to treat GA and some GA could be followed up. Therefore no consensus of treatment of GA is present now. Etiology, pathogenesis, diagnosis and treatment of GA were included in this article.