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Objective: To analyze the clinical characteristics and prognosis of Chinese patients with apical hypertrophic cardiomyopathy (AHCM)., Methods: A total of 188 patients with AHCM diagnosed at Fuwai Hospital were included in this retrospective study. Clinical characteristics, mortality and cardiovascular morbidity were analyzed. A multiple logistic regression was performed to adjust for potential confounding factors., Results: Males predominated with a number of 139 (73.9%) in this cohort. Patient's age ranged from 15 to 81 (51.9 ± 12.6) years. There were 120 patients (63.8%) with "pure" type and 68 patients (36.2%) with "mixed" type of AHCM, 171 patients were followed up for (5.0 ± 3.0) years, cardiovascular mortality was 1.2%, 28 patients (16.4%) experienced one or more cardiovascular events., Conclusion: The prevalence of AHCM is high in Chinese HCM patients, pure type AHCM is more common, and AHCM patients have a benign clinical course.

The two kinds of new nanocomposites BiVO4/TiO2 nanowires were synthesized by hydrothermal process. Their crystal structure, morphology and photocatalytic activities for degradation of methylene blue solution were characterized using various measurement techniques. The XRD results indicate that they are made up of monoclinic BiVO4 and anatase TiO2 phases. The SEM, TEM and HRTEM images show that the two samples include BiVO4 nanoparticles supported onto TiO2 nanowires. The UV-Vis absorption spectra reveal that the absorption edges of the samples exhibit red-shift in comparison with that of the pure TiO2 nanowires. The measurement results for the visible-light photodegradation of methylene blue show that the nanocomposite sample prepared from the layered titanate nanowires with Bi3+ has the highest photocatalytic activity.

The index of local Moran's I is a useful tool for identifying hotspots of soil Ni and Cr, and for classifying them into spatial clusters and spatial outliers. To identify hotspots of vegetable soils Ni and Cr in high-incidence area of liver cancer, Shunde area of Foshan City, Pearl River Delta Economic Zone, 208 topsoil samples were collected from vegetable fields to measure the contents of nickel (Ni) and chromium (Cr). The results showed that the mean concentrations of two heavy metals Ni, Cr were 33.21 mg/kg, 80.84 mg/kg, respectively, Which were 130%, 60% higher than their soil background values of Guangdong Province, respectively. Generally, Ni is partly accumulated in soil but the accumulation of Cr is not obvious at all. The local Moran's I of Ni and Cr was calculated using 3 000, 6 000, 9 000 m as distance bands, respectively. The hotspots of Ni and Cr elements in soils were identified by local Moran's I which computed based on 6 000 m; "individual hotspots" are in the north which were affected by anthropogenic factors; "regional hotspots" are in the south which were controlled by parent materials. Moreover, the distributions of "regional hotspots" of Ni, Cr are the same as that of the highest mortality rate of liver cancer, this consistence could come up with a research direction that could reveal environmental etiologic factors of liver cancer.

The sample of NaYF4:Eu,Tm,Yb was synthesized by coprecipitation method. The emission of NaYF4:Eu,Tm,Yb excited by 360 nm is blue light with the peak at 452 nm from the transition of (1)D2-->(3)F4 of Tm3+. After being excited by 395 nm, NaYF4:Eu,Tm,Yb emits orange light with the peak at 591 nm originating from the transition of (5)D0-->(7)F1 of Eu3+. When excited by 409 nm, NaYF4:Eu,Tm,Yb emits red light with the peak at 613 nm from the transition of (5)D0-->(7)F2 of Eu3+. The color of upconversion luminescence of NaYF4:Eu,Tm,Yb excited by 980 nm was blue and red. The upconversion spectrum exhibits distinct emission peaks at 459, 478 and 641 nm. The blue light comes from the transition of (1)G4--(3)H6 and (1)D2-->(3)F4 of Tm3+. The absorption spectrum was also researched. The red light results from the transition of (1)G4--(3)F4 of Tm3+. The slope of the emission of 474 and 646 nm is 2.1 and 2.4 respectively. The emission of 478 and 641 nm is all due to three photon process. The structural properties of sample were characterized by X-ray diffraction (XRD) and scanning electron microscopy (SEM). The results show that NaYF4:Tm3+,Yb3+ prepared by coprecipitation method exhibits a hexagonal crystal.

The ZBLAN : Nd3+, Tm3+, Yb3+ upconversion materials were prepared by high-temperature solid method. The concentrations of Tm3+ and Yb3+ were 0.01% and 0.3% respectively. The concentration of Nd3+ changed in the range from 0.1% to 2%. The absorption spectrum of ZBLAN : Nd3+, Tm3+, Yb3 in all samples from 300 to 1 000 nm was measured at room temperature. The upconversion emission was observed when excited by 798 nm infrared light. The material samples emitted relatively strong multi-band (the red, blue and green color) visible light. Based on the experiment, the multi-band visible spectral lines were analyzed, and the energy level transition mechanism was given. The blue light results from the transition of 1G4 --> 3 H6 of Tm3+, the green light is from the transition of 2 H7/2 --> 4 I9/2 of Nd3+, and the red light originates from the transition of 2 H11/2 --> I9/2 of Nd3+. The results show that the upconversion mechanism includes excited state absorption, energy transfer, cross relaxation and so on. The energy transfer processes between Nd3+, Tm3+ and Yb3+ ions both forward and backward prove to be the origin of upconversion emissions. The effect of rare earth doping concentration on the energy upconversion efficiency was analyzed, according to the different upconversion light emitting intensity from samples with different Tm3+ mol concentrations. The upconversion luminescence increased with the Nd3+ concentration and got its peak at 1.5%.

This study was purposed to detect the expressions of CD271, CD133 and CD34, and to analyze the correlation of CD271 with CD133 and CD133 with CD34 expressions. The human bone marrow cells (BMCs) and mononucleated cells (MNCs) were detected by flow cytometry with CD45-PerCP, CD271-FITC, CD133-PE and CD34-FITC labelling according to different combinations of design, cells were located and selected repeatedly by FSC, SSC and CD45 after acquirement, then the expressions of CD271, CD133 and CD34 were detected by flow cytometry. The results showed that the expressions of CD271, CD133 and CD34 in BMCs were 0.16%, 0.20% and 0.43% respectively, while their expressions were 0.49%, 0.47% and 1.07% respectively after isolation of MNCs. The co-expressions of CD271(+)CD133(+) before and after isolation of MNCs were (0.02 +/- 0.01)% and (0.03 +/- 0.02)% respectively. The co-expression of CD133(+) and CD34(+) before and after isolation of MNCs were (0.18 +/- 0.11)% and (0.42 +/- 0.23)% respectively (p < 0.01); meanwhile about 90% of cells with CD133(+) expressed CD34 and 40% of cells with CD34(+) expressed CD133. It is concluded that the established method of detection using flow cytometry with three color fluorescence labelling can be used to detect expression of CD271, CD133 and CD34 in BMCs. The cells with CD271 are different from cells with CD133 and CD34, which suggests that the CD271 may be of important role in evaluating and guiding the clinical application of BM MSCs.

The samples of surface soil, deep soil, and vegetables were collected from the liver cancer's high- and low incidence areas in Zhujiang River Delta to study the relationships between soil Mn forms and vegetables' Mn enrichment. The results showed that the soil Mn in study area was mainly derived from parent materials, and rarely come from human activities. The average soil Mn content in liver cancer's high incidence area was 577.65 mg x kg(-1), being significantly lower than that of liver cancer's low incidence area (718.04 mg x kg(-1)) and whole country (710 mg x kg(-1)). The Mn forms in high incidence area were mainly of residual Mn and Fe-Mn oxide, and less of water soluble Mn and exchangeable Mn, with the sum of the latter two's distribution coefficients being not higher than 4%. In low incidence area, the distribution pattern of soil Mn forms was similar to that in high incidence area, but the absolute contents of the Mn forms were significantly higher. Soil total Mn and soil pH had significant effects on soil Mn forms. There existed significant positive correlations between soil total Mn and the Mn forms of Fe-Mn bound, humic acid bound, carbonate bound, and residual, and negative correlations between soil pH and soil water soluble and organic bound Mn forms. Among the test five kinds of vegetables, Youmai lettuce and Chinese cabbage in liver cancer' s high incidence area had a significantly lower Mn content than in low incidence area, while the other three had less difference. The Mn enrichment in test vegetables was positively correlated with to the content of soil available Mn (sum of water soluble Mn and exchangeable Mn), but had no correlations with the contents of soil total Mn and other Mn forms.

The optically variable pigments with four symmetrical configurations were obtained by using the mica titanium as the host materials, which was pretreated in acid and alkaline condition. The reflection differences between the host materials and the coatings were increased by optimizing the number of layers and the arrangement order. The optically variable effect was investigated by X-Rite MA86II five angles spectrophotometer. The impact of symmetrical configurations on improving the color travel effect was studied, and the influence of different coating materials on the hue and the color travel effect was researched. The results show that the reflection rate and the color travel effect of the pigment were improved by coating another material on three symmetrical configurations.

Alkali earth chlorosilicate of the type Sr(4-x)Ca(x)Si3O8Cl4 was synthesized through the high temperature solid state method. According to the Van Uitert experimental equation, luminescence properties and crystal-lattice environment of Eu2+ in Sr(4-x) Ca(x)Si3O8Cl4 crystal were discussed. The possibilities of two Eu2+ emission centers, viz. blue and greenish-yellow centers, were found and their corresponding relationships with spectra were also discussed. When the doping amount of calcium(x) varied between 0 and 0.5, Ca2+ ions were embedded in the host lattice of Sr4Si3O8Cl4, and the luminescence of blue center, which was ascribed to the emission of Eu2+ that substituted the octa-coordination Sr2+ sites, dominated and showed blue-green luminescence. Sr(4-x)Ca(x)Si3O8Cl4:yEu2+ exhibited greenish-yellow luminescence when the range of x was between 0.5 and 2. This was due to the fact that the Eu2+ emission originated from the formation of an impurity-trapped exciton state. Greenish-yellow emission center was located in the impurity-trapped exciton state which was the lowest excited state of this system, and the Eu2+ emission was at long wavelengths, and a large Stokes shift was observed.