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Objective To analyze the clinical and pathological factors affecting pathological complete response (pCR) of triple-negative breast cancer (TNBC) after neoadjuvant chemotherapy (NAC). Methods A retrospective analysis was conducted in 78 TNBC patients treated with NAC and surgery in The First Affiliated Hospital of Xinjiang Medical University from January 2018 to September 2023. The patients were divided into pCR group (n=28) and non-pCR group (n=50) based on whether they had achieved pCR or not. Logistic regression analysis was used to investigate the clinical and pathological factors affecting pCR. The pCR rate and incidence of adverse reactions after NAC between TP regimen (taxane+platinum) and TAC regimen (taxane+anthracycline+cyclophosphamide) were compared. Results The overall pCR rate was 35.9%. There were statistically significant differences between the two groups of patients in tumor diameter, chemotherapy cycle, chemotherapy regimen, paclitaxel type, human epidermal growth factor receptor 2 (HER-2) expression, Ki-67 expression, and androgen receptor (AR) positive expression (P＞0.05). Multivariate logistic regression analysis showed that tumor diameter ≤ 3 cm was an independent favorable factor of pCR(OR=4.191, 95%CI: 1.246-14.094, P=0.021), and AR positive expression was an independent unfavorable factor of pCR (OR=0.124, 95%CI: 0.020-0.784, P=0.027). In addition, the pCR rate of the TP regimen was significantly better than that of the TAC regimen ［54.8%(17/31) vs 28.1%(9/32), χ2=4.636, P=0.031］, and there was no significant difference in the incidence of adverse reactions between two groups (P＞0.05). Conclusion TP or TAC regimen and albumin bound paclitaxel in NAC for TNBC is beneficial for achieving pCR status, but the pCR rate of TP regimen is better than that of TAC regimen, and the incidence of adverse reactions is comparable. The pCR rate is higher for tumor diameter≤3 cm, while low expression of HER-2, Ki-67, or AR indicates a lower pCR rate. AR positive expression is an independent unfavorable factor of pCR.

以内蒙古油莎豆主要栽培品种（圣漠1号、中油莎1号、丰产1号和达旗1号）为材料，对4个不同品种油莎豆的基本营养成分、脂肪酸组成、VE含量和矿质元素含量进行测定，分析比较不同品种油莎豆的营养价值和品质差异。结果表明：4个不同品种油莎豆的基本营养成分存在差异，但均富含淀粉（21.15%～25.40%）、膳食纤维（20.15%～21.95%）、脂肪（23.35%～25.60%）和总糖（17.10%～17.95%），可作为提取淀粉、糖类和脂肪的优良原料；各品种油莎豆脂肪酸组成基本相同，以油酸（9.120 0～10.600 0 g/100 g）、亚油酸（0.051 8～1.515 0 g/100 g）和棕榈酸（0.037 8～1.995 0 g/100 g）为主，可作为生产油酸和优质食用油的原料；4个品种油莎豆均富含VE（4.39~559 mg/100 g），且均富含Ca(476～1 253 mg/kg)、Fe（142.5～216.5 mg/kg）、Zn（10.15～17.95 mg/kg）和Se（0053～0.072 mg/kg）。圣漠1号可以用来制作油莎豆面粉及其制品，中油莎1号适用于提取高品质的油莎豆油，达旗1号更适合提取高纯度的油酸，而丰产1号的各种营养物质比较均衡。 The basic nutrients, fatty acid composition, VE content and mineral elements contents of four cultivars of Cyperus esculentus were measured with main cultivars of Cyperus esculentus (Shengmo No.1, Zhongyousha No.1, Fengchan No.1 and Daqi No.1) in Inner Mongolia as materials to analyze and compare the differences in nutritional value and quality of different cultivars of Cyperus esculentus. The results showed that there were differences in the basic nutrients of four different varieties of Cyperus esculentus, but they were all rich in starch（21.15%-25.40%）, dietary fiber（20.15%-21.95%）, fat（23.35%-25.60%） and total sugar（17.10%-17.95%）, and could be used as raw materials for extracting starch, sugar and fat. The fatty acid composition of four varieties was basically the same, mainly oleic acid （9.120 0-10.600 0 g/100 g），linoleic acid（0.051 8-1.515 0 g/100 g）and palmitic acid（0.037 8-1.995 0 g/100 g）, which could be used as raw materials for the production of oleic acid and high-quality edible oil. Furthermore,they were rich in VE(4.39-5.59 mg/100 g), and calcium(476-1 253 mg/kg), iron（142.5-216.5 mg/kg）, zinc（10.15-17.95 mg/kg） and selenium（0053-0.072 mg/kg）. Shengmo No.1 could be used to make Cyperus esculentus flour and its products, Zhongyousha No.1 was suitable for extracting high quality Cyperus esculentus oil, Daqi No.1 was more suitable for extracting high purity oleic acid, and Fengchan No.1 had a relatively balanced variety of nutrients.