25 results on '"Eosinophilia diagnosis"'
Search Results
2. [Clinical characteristics of 267 children with eosinophilic gastrointestinal disease: a multicenter study].
- Author
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Zhan CL, You JY, Li XQ, Wang Y, Mei XQ, and Wan SH
- Subjects
- Infant, Child, Preschool, Humans, Vomiting, Eosinophilia diagnosis, Eosinophilia drug therapy, Anti-Allergic Agents, Enteritis, Gastritis
- Abstract
Objectives: To explore the clinical manifestations, endoscopic findings, histopathological changes, treatment, and prognosis of eosinophilic gastrointestinal disease (EGID) in children, with the aim of enhancing awareness among pediatricians about this condition., Methods: Data of 267 children with EGID were prospectively collected from January 2019 to July 2022 at Jiangxi Children's Hospital, Hunan Children's Hospital, and Henan Children's Hospital. The age of onset, symptoms, physical signs, laboratory examination results, endoscopic findings, histopathological changes, and treatment outcomes were observed., Results: Among the 267 children with EGID, the majority had mild (164 cases, 61.4%) or moderate (96 cases, 35.6%) clinical severity. The disease occurred at any age, with a higher prevalence observed in school-age children (178 cases). The main symptoms in infants were vomiting and hematemesis, while in toddlers, vomiting and bloody stools were prominent. Abdominal pain and vomiting were the primary symptoms in preschool and school-age children. Nearly half (49.4%) of the affected children showed elevated platelet counts on hematological examination, but there was no significant difference in platelet counts among children with mild, moderate, and severe EGID ( P >0.05). Endoscopic findings in EGID children did not reveal significant specificity, and histopathological examination showed no specific structural damage. Among them, 85.0% (227 cases) received acid suppression therapy, 34.5% (92 cases) practiced dietary avoidance, 20.9% (56 cases) received anti-allergic medication, and a small proportion (24 cases, 9.0%) were treated with prednisone. Clinical symptoms were relieved in all patients after treatment, but three cases with peptic ulcers experienced recurrence after drug discontinuation., Conclusions: Mild and moderate EGID are more common in children, with no specific endoscopic findings. Dietary avoidance, acid suppression therapy, and anti-allergic medication are the main treatment methods. The prognosis of EGID is generally favorable in children.
- Published
- 2024
- Full Text
- View/download PDF
3. [Guideline of the diagnosis and treatment of eosinophilic disorders (2024)].
- Subjects
- Humans, World Health Organization, Clone Cells, Eosinophilia diagnosis, Eosinophilia therapy
- Abstract
The eosinophilias encompass a broad range of nonhematologic (secondary or reactive) and hematologic (primary or clonal) disorders with potential for end-organ damage. Based on new clinical data and increased understanding of disease molecular genetics, the World Health Organization (WHO) and the international consensus classification (ICC) has provided updated criteria and classifications for eosinophilic disorders in 2022. This guideline represents an update of Chinese expert consensus on the diagnosis and treatment of eosinophilia published in 2017 and aim to provide Chinese hematologist with clear guidance on management for eosinophilic disorders.
- Published
- 2024
- Full Text
- View/download PDF
4. [Immune checkpoint inhibitor-induced eosinophilic fasciitis: a case report and literature review].
- Author
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Ouyang ZM, Ma JD, Yang ZH, Mo YQ, Zou YW, and Dai L
- Subjects
- Male, Humans, Middle Aged, Immune Checkpoint Inhibitors therapeutic use, Myalgia, Eosinophilia diagnosis, Eosinophilia drug therapy, Eosinophilia pathology, Fasciitis chemically induced, Skin Diseases complications, Skin Diseases drug therapy
- Abstract
A 58-year-old male patient with angioimmunoblastic T-cell lymphoma developed a rash and skin tightness on the face, limbs, and trunk together with joint stiffness and dysfunction after 6 months of treatment with the programmed cell death protein-1 inhibitor camrelizumab. Laboratory tests revealed progressive eosinophilia over 6 months, with the eosinophil count increasing from 0.07×10
9 /L to 3.3×109 /L. Magnetic resonance imaging showed thickened skin of both forearms, while T2 -weighted imaging showed markedly increased signal intensity within the myofascia. Skin biopsy of the right forearm showed thickened and fibrosed fascia and infiltration of inflammatory cells, including lymphocytes, plasma cells, and eosinophils. The patient was diagnosed with immune checkpoint inhibitor (ICI)-induced eosinophilic fasciitis (EF). After beginning treatment with methylprednisolone (40 mg daily), methotrexate (10 mg/week), and baricitinib (4 mg daily), his symptoms of skin tightness and joint dysfunction significantly improved within 1 month, and his peripheral blood eosinophil count decreased to 0.17×109 /L. ICI-induced EF is a rare immune-related adverse reaction. To date, only 20 cases have been reported in published foreign literature, and their clinical characteristics are summarized here. The time from ICI treatment to EF was 12 (8,15) months, and the main clinical manifestations included skin involvement ( n =19), joint dysfunction ( n =11), myalgia/muscle weakness ( n =9), and peripheral eosinophilia ( n =16). After treatment, the clinical symptoms of EF improved in 17 patients, and eosinophil counts returned to normal after 3 (1,8) months. EF is a dysfunctional adverse response to ICI therapy. Tumor patients undergoing immunotherapy should be monitored for symptoms of EF. Early treatment is essential for preventing complications.- Published
- 2023
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5. [Cardiac Mechanical Valve Thrombosis with Eosinophilia: A Case Report].
- Author
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杨 保丰, 闫 晓宝, 刘 新, and 闫 培腾
- Subjects
- Humans, Eosinophilia complications, Eosinophilia diagnosis, Thrombosis diagnosis, Thrombosis etiology, Heart Diseases complications
- Published
- 2022
- Full Text
- View/download PDF
6. Recurrent abdominal pain, peritoneal effusion, and eosinophilia in a boy aged 17 years.
- Author
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Yang K, Luo RH, and Sun YL
- Subjects
- Abdominal Pain etiology, Ascitic Fluid, Humans, Male, Enteritis, Eosinophilia diagnosis, Eosinophilia etiology, Gastritis
- Abstract
A boy, aged 17 years, was admitted again due to abdominal pain, diarrhea, and eosinophilia for 3 years, which worsened for 3 days. Three years ago, the boy suffered from abdominal pain and diarrhea after eating yogurt; color Doppler ultrasound showed a large amount of peritoneal effusion, and routine blood test, bone marrow cell morphology, and ascites histological examination showed a large number of eosinophils. Three days ago, he was admitted again due to abdominal pain and diarrhea. The gastrointestinal endoscopy showed eosinophil infiltration in the angle of stomach. The boy was diagnosed with eosinophilic gastrointestinal disease (eosinophilic gastroenteritis). He was improved after the treatment with glucocorticoids and dietary avoidance, and no recurrence was observed during the one-year follow-up. It is concluded that for children who attend the hospital due to gastrointestinal symptoms such as abdominal pain and diarrhea, if there is an increase in peripheral blood eosinophils, it is necessary to consider the possibility of eosinophilic gastrointestinal disease, and eosinophil infiltration and abnormal eosinophil count in gastrointestinal tissue based on endoscopic biopsy may be the key to diagnosis.
- Published
- 2021
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- View/download PDF
7. [Clinical diagnosis and treatment of eosinophilic otitis media].
- Author
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Zhang YZ, Wei XY, Chen ZC, Sun M, Cheng Y, Gao Y, Chen FY, Hu J, Xu M, Zhang Q, and Fan MY
- Subjects
- Glucocorticoids, Humans, Retrospective Studies, Eosinophilia diagnosis, Eosinophilia therapy, Otitis Media, Otitis Media with Effusion diagnosis, Otitis Media with Effusion therapy
- Abstract
Objective: Eosinophilic otitis media(EOM) is a rare,refractory otitis media.This article summarizes the clinical manifestations and diagnosis and treatment experience of EOM. Method: Retrospective analysis of 3 cases of EOM patients with medical history, clinical manifestations, and related auxiliary examinations.Discuss the EOM clinical features,diagnosis and treatment in conjunction with the literature. Result: The clinical features of 3 patients with EOM were summarized as: a large amount of yellowish white secretions or polyps formation, obvious itching symptoms; polyp biopsy showed a large amount of eosinophil infiltration;topical use of hormone-containing ear drops treatment is effective. Conclusion: EOM is a new type of chronic otitis media.It has characteristic clinical manifestations,a comprehensive treatment based on glucocorticoids should be given.., Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose., (Copyright by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.)
- Published
- 2019
- Full Text
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8. [Clinical analysis of 3 cases of eosinophilic granulomatosis with polyangiitis].
- Author
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Shi X, Qiu RH, Lai ZD, Qiu MZ, Wei SS, Xie JX, Zhang XX, Deng FG, Li J, Gu YY, Dai L, Zhang QL, Zhang NF, Li SY, and Chen RC
- Subjects
- Adult, Asthma etiology, Churg-Strauss Syndrome complications, Eosinophilia blood, Female, Granulomatosis with Polyangiitis complications, Humans, Prognosis, Churg-Strauss Syndrome physiopathology, Eosinophilia diagnosis, Granulomatosis with Polyangiitis physiopathology, Lung pathology
- Abstract
Objective: To improve the clinical recognition of eosinophilic granulomatosis with polyangiitis(EGPA) in clinical manifestations, diagnosis and treatment. Methods: The clinical manifestations, pathological characteristic, imaging manifestations, diagnosis and the therapy of three patients with EGPA were presented. Results: These 3 patients had asthma-like symptoms and extrapulmonary manifestations of systemic vasculitis. They were 20, 40 and 44 years old. All of them were female.They denied exposure or contact. Chest radiographic examination showed that the most common features were nodule shadow and tree-in-bud in the lung. The pathological manifestation was characterized by hypereosinophilia, high total IgE(over 300 KU/L) and high CRP(over 14.1mg/L). The FeNO of 2 patients was over 100ppb. The ANCA of these 3 patients was negative. The pulmonary pathology was observed had eosinophil infiltration in the alveolar, interstitial and vessel for 3 cases. The clinical manifestations were nonspecific. All patients were treated by glucocorticoid and immune-inhibitor(alkylating agents or purine synthesis inhibitors) therapy. Because patients were complicated with other organs involved, they needed long-time treatment. Conclusions: This disease is diverse and complex, with a lack of pathognomonic symptoms. We should highly suspect eosinophilic granulomatosis with polyangiitis, when the patients present severe asthma and eosinophilia. Early detection, early treatment, and the prognosis could be better.
- Published
- 2018
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9. [Clinical analysis of eosinophilic gastroenteritis in 71 children].
- Author
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Han XX, Guan DX, Zhou J, Yu FH, Wang GL, Mei TL, Guo S, Fu LB, Zhang J, Shen HQ, and Xu XW
- Subjects
- Adolescent, Child, Child, Preschool, Female, Gastroenteritis, Humans, Infant, Male, Retrospective Studies, Enteritis complications, Enteritis diagnosis, Enteritis therapy, Eosinophilia complications, Eosinophilia diagnosis, Eosinophilia therapy, Gastritis complications, Gastritis diagnosis, Gastritis therapy
- Abstract
Objective: To summarize the clinical data including manifestations, diagnosis, treatment and prognosis of eosinophilic gastroenteritis (EGE) in children. Methods: A retrospective analysis was performed in 71 patients with pathologically proven EGE at Beijing Children's Hospital Affiliated to Capital Medical University from January 2008 to January 2017. Their clinical manifestations, laboratory and imaging examinations, endoscopic findings, histopathological examinations, and treatment were collected and analyzed. Results: Among 71 EGE cases, 47 (66%) cases were male and 24 (34%) cases were female, and the median age was 9.2 (0.2-16.5) years old. The main clinical manifestations included abdominal pain (76%, 54/71), vomiting (68%, 48/71), anorexia (54%, 38/71), weight loss (38%, 27/71), and diarrhea (37%, 26/71). There were 27 cases (38%) with a history of allergic diseases or family history. The median absolute value of eosinophil in peripheral blood of the 71 patients was 0.4 (0-36.8)×10(9)/L, and 27 cases (38%) showed an increase in eosinophil counts. Serum IgE was measured in 52 patients (104.3 (3.4- 3 000.0)×10(3) U/L), and 30 patients (58%) showed an increase in serum IgE. A large number of eosinophils ((41.0±8.5)/HP) were found in 3 patients' ascites. The endoscopic examination of upper gastrointestinal tract revealed hyperemic edema in 62 cases (87%), plaque in 44 cases (62%), erosion in 17 cases (24%) and ulceration in 16 cases (23%). Histopathologically, in 8 cases (11%) the disease involved both stomach and duodeneum, in 21 cases (30%) involved stomach only, and in 37 cases (52%) involved duodeneum only. In addition, in 6 cases (8%) the disease involved esophagus and in 10 cases (14%) involved colorectum. Microscopically, eosinophil counts averaged 67/HP, 33/HP, 40/HP and 38/HP in esophageal, gastric, duodenal and colorectal mucosa respectively. A total of 34 cases were treated with glucocorticoid, and all these patients had alleviation of symptoms, which occurred within 14.9 days on average, but EGE recurred in 11 cases (32%). Conclusions: The clinical symptoms and endoscopic findings of EGE are diverse and nonspecific. Histopathological examination of gastrointestinal mucosa is particularly important for the diagnosis. Glucocorticoid treatment is effective, but the patients with EGE are prone to relapse.
- Published
- 2018
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10. [The value of sinonasal CT scan in diagnosing of eosinophilic chronic rhinosinusitis with nasal polyps].
- Author
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Meng YF, Lou HF, Wang CS, and Zhang L
- Subjects
- Breath Tests, Chronic Disease, Eosinophils, Ethmoid Sinus diagnostic imaging, Exhalation, Female, Humans, Hypersensitivity diagnosis, Leukocyte Count, Male, Maxillary Sinus diagnostic imaging, Nasal Polyps diagnostic imaging, Nitric Oxide analysis, ROC Curve, Rhinitis diagnostic imaging, Sinusitis diagnostic imaging, Skin Tests, Eosinophilia diagnosis, Nasal Polyps diagnosis, Rhinitis diagnosis, Sinusitis diagnosis, Tomography, X-Ray Computed
- Abstract
Objective: To compare the value of sinonasal CT scan with other clinical parameters in the pre-diagnosis of eosinophilic chronic rhinosinusitis with nasal polyps (eCRSwNP). Methods: From January to May of 2016, One hundred and fifty consecutive CRSwNP patients (90 eCRSwNP and 60 non-eosinophilic CRSwNP) undergoing endoscopic functional sinus surgery in Beijing Tongren Hospital were recruited in this study. Preoperative CT scan, skin prick test (SPT) and oral fractional exhaled nitric oxide (FeNO) measurements were performed in each patient and full blood count with differential analysis was performed within 1 week before surgery. t test and X2 test were used to compare the age, gender, history of surgery, onset of asthma, history of allergy, CT scores' ratio for the ethmoid sinus and maxillary sinus (E/M ratio) and presence of osteoneogenesis of two groups. Mann-Whitney analysis was used to compare the total Lund-Mackay scores, FeNO and blood eosinophil counts of two groups. Logistic regression analysis and receiver operating characteristic (ROC) curve were used to assess the predictive value of clinical parameters. Results: E/M ratio, FeNO, blood eosinophil percentage of eCRSwNP group was significantly higher than those of non-eosinophilic CRSwNP group [3.56±0.37 vs 1.80±0.10, (34.4±18.1) μg/L vs (22.1±11.7) μg/L, 8.19%±1.50% vs 4.55%±5.60%; χ(2) value was 0.900; t value was 0.994 and 0.900, respectively; all P <0.05]. E/M ratio had the highest predictive value, with area under curve (AUC) value of 0.938. The cut-off point of 2.59 for E/M ratio demonstrated a sensitivity of 94.3% and a specificity of 89.6% for eCRSwNP. Conclusion: The E/M ratio is a more useful predictor in the diagnosis of eCRSwNP compared to other clinical parameters.
- Published
- 2017
- Full Text
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11. [Clinical characteristics and etiology of children with hypereosinophilia].
- Author
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Xiaohong C, Yiping XU, and Meiping LU
- Subjects
- Child, Diagnosis, Differential, Enteritis diagnosis, Eosinophilia diagnosis, Fever etiology, Gastritis diagnosis, Humans, Pancreatitis etiology, Retrospective Studies, Urinary Tract Infections etiology, Enteritis complications, Eosinophilia complications, Gastritis complications
- Abstract
Objective: To analyze the clinical characteristics and etiology of hypereosinophilia in children., Methods: Clinical data of 88 children with hypereosinophilia admitted in Children's Hospital of Zhejiang University School of Medicine during April 2009 and May 2015 were retrospectively reviewed. The clinical manifestations, etiologies, and the correlation of disease severity with different etiologies were analyzed., Results: The main clinical manifestations were fever, abdominal pain, cough and/or tachypnea, skin rash, hemafecia and diarrhea, which were observed in 19 (21.6%), 15 (17.0%), 14 (15.9%), 13 (14.8%), 11 (12.5%) and 6 (6.8%) cases, respectively. For etiologies, there were 28 cases (31.8%) induced by infections, including 11 cases of acute bronchial pneumonia, 9 cases of parasite infection, 4 cases of septicemia, 2 cases of urinary system infection, 1 case of cellulitis and 1 case of cholecystitis complicated with pancreatitis. The etiologies for the rest cases were allergic diseases (25 cases, 28.4%), eosinophilic gastroenteritis (20 cases, 22.7%), immunodeficiency (3 cases, 3.4%, all were moderate to severe eosinophilia), ABO hemolysis (2 cases, 2.3%), hematologic neoplasms (2 cases, 2.3%), eosinophilic cystitis (1 case, 1.1%), eosinophilic granulomatosis with polyangitis (1 case, 1.1%), nephrotic syndrome (1 case, 1.1%), and 5 cases (5.7%) were of unknown causes., Conclusions: Fever, abdominal pain, cough and/or tachypnea are the most common clinical manifestations in children with hypereosinophilia. Infection, allergic diseases and eosinophilic gastroenteritis are the most common etiologies, and parasites are the most common pathogen identified. Differential diagnosis of primary immunodeficiency should be considered in children with moderate to severe eosinophilia.
- Published
- 2016
- Full Text
- View/download PDF
12. [Predictive significance of tissue eosinophilia for nasal polyp recurrence].
- Author
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Wang CS, Lou HF, Meng YF, Piao YS, and Zhang L
- Subjects
- Asthma complications, Chronic Disease, Eosinophilia diagnosis, Eosinophils, Humans, Leukocyte Count, Prognosis, ROC Curve, Recurrence, Regression Analysis, Rhinitis complications, Sensitivity and Specificity, Sinusitis complications, Eosinophilia complications, Nasal Polyps etiology
- Abstract
Objective: To evaluate the association between clinical parameters, especially tissue eosinophilia, and chronic sinusitis with nasal polyps (CRSwNP) recurrence. To identify optimal criteria of tissue eosinophilia as a predictor for recurrence., Methods: Two hundred and forty-eight CRSwNP patients were enrolled in this study. The demographic and clinical features were compared between recurrence and no recurrence groups. Mucosal specimens were assessed for the presence of tissue inflammatory cells. Factors associated with polyp recurrence were analyzed by Logistic regression analysis and optimal cutoff point of the predictor for nasal polyp recurrence was determined by receiver operating characteristic curve. SPSS 19.0 software was used to analyze the data., Results: The recurrence rate was 55.6%(138/248 patients) in this cohort. Tissue and peripheral eosinophilia, comorbid asthma, olfactory score and Lund-Mackay score were significantly correlated with polyp recurrence(all P<0.01). As a predictor for recurrence, tissue eosinophil accumulation outweighed other parameters. A cutoff value of 27% for tissue eosinophil percentage was able to predict recurrence with 96.4% sensitivity and 92.7% specificity (AUC=0.971, P<0.001)., Conclusions: Tissue eosinophilia provides valuable information regarding to polyp recurrence. Tissue eosinophil proportion equal to or over 27% may be regarded as the prognostic criterion for nasal polyp recurrence.
- Published
- 2016
- Full Text
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13. [Application of magnetic resonance enterography for diagnosis of small intestinal diseases in children].
- Author
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Lou J, Lai C, Chen F, and Chen J
- Subjects
- Capsule Endoscopy, Child, Colonoscopy, Enteritis diagnosis, Eosinophilia diagnosis, Female, Gastritis diagnosis, Gastrointestinal Hemorrhage diagnosis, Humans, Intestinal Obstruction diagnosis, Male, Crohn Disease diagnosis, Intestine, Small physiopathology, Magnetic Resonance Imaging
- Abstract
Objective: To explore the value of magnetic resonance enterography (MRE) for diagnosis of small intestinal diseases in children., Method: A total of 92 children who received MRE from July 2009 to January 2014 were included into this study. The clinical value of MRE in children was evaluated by describing the image presentation of MRE based on clinical diagnosis., Result: All the 92 cases (average age was nine year and one month, among whom 61 were boys, and 31 were girls) received MRE examination with good tolerance and had no complications. Eleven cases (12%) did not show good distension of small bowel loop during MRE and could not evaluate the bowel wall pathologies correctly. A total of 66 cases (72%) showed pathological MRE images. All patients with Crohn's disease showed pathological gut and 53% (16/30) showed extramural changes with MRE, 97% (29/30) showed colon lesions with colonoscopy, 73% (20/22) showed small intestine lesions with capsule endoscopy. All patients with intestinal obstruction (7 cases) showed abnormal gut distension, 4 of whom showed obstruction point. Five patients with small intestinal neoplasms showed the mass with MRE. One of the patients with intestinal tuberculosis showed enlarged lymph nodes with ring strengthening. Nine cases with eosinophilic gastroenteritis (75%) and 1 case of gastrointestinal bleeding showed increased contrast enhancement for small bowel. The main finding of MRE were abnormal wall thickening and enhancement, gut stricture, bowel expansion, etc., Conclusion: MRE for children was safe and reliable. It can be a suitable method for determining the location and extent of gut for small intestinal diseases, especially suitable for Crohn's disease in children.
- Published
- 2016
- Full Text
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14. [Misdiagnosis of childhood eosinophilic gastroenteritis: an analysis of 12 cases].
- Author
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Chen CB, You JY, and Zhang WT
- Subjects
- Adolescent, Child, Child, Preschool, Female, Humans, Male, Retrospective Studies, Diagnostic Errors, Enteritis diagnosis, Eosinophilia diagnosis, Gastritis diagnosis
- Published
- 2015
15. [A patient with eosinophilic gastroenteritis presenting with acute pancreatitis].
- Author
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Zhu B, Bai H, and Wu J
- Subjects
- Humans, Enteritis diagnosis, Eosinophilia diagnosis, Gastritis diagnosis, Pancreatitis diagnosis
- Published
- 2015
16. [Case of eosinophilic gastroenteritis].
- Author
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Liu P, Zou W, and Yu Xueping
- Subjects
- Enteritis diagnosis, Eosinophilia diagnosis, Gastritis diagnosis, Humans, Male, Middle Aged, Acupuncture Therapy, Enteritis therapy, Eosinophilia therapy, Gastritis therapy
- Published
- 2015
17. [The clinico-pathological manifestation of cardiac involvement in eosinophilic diseases].
- Author
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Tian Z, Fang Q, Zhao DC, Cui QC, Liu YT, Zeng Y, Li MT, and Jiang XC
- Subjects
- Adult, Aged, Endocardium pathology, Eosinophilia complications, Eosinophilia diagnosis, Female, Heart Diseases diagnosis, Heart Diseases etiology, Humans, Male, Middle Aged, Myocardium pathology, Prognosis, Eosinophilia pathology, Heart Diseases pathology
- Abstract
Objective: To investigate the clinical and pathological features of eosinophilic diseases with cardiac involvement., Methods: We analyzed the clinical and cardiac pathological data of 7 patients with eosinophilic diseases with cardiac involvement under endomyocardial biopsy or autopsy., Results: Seven patients (5 male, average age 51 years) were enrolled. Four patients were diagnosed as idiopathic hypereosinophilic syndrome and three were Churg-Strauss syndrome. Peripheral blood eosinophilia count increased significantly in all patients. Cardiac involvement included angina pectoris, myocardial infarction, heart failure, presyncope and sudden death. Electrocardiogram showed cardiac ischemia, bundle branch block and third degree atrioventricular block. Echocardiography suggested ventricular and atrial enlargement, decreased ventricular systolic function, pulmonary hypertension, valvular prolapse and insufficiency and endocarditis. Pathology displayed infiltration of eosinophils, formation of granulomata, necrotizing vasculitis, myocardial necrosis and endomyocardial fibrosis in heart. Coronary artery could be also affected and led to myocardial infarction., Conclusions: Cardiovascular complications of eosinophilic diseases are a major source of morbidity and mortality in these disorders. The manifestations are multiple and early recognition and treatment with steroid and immunosuppressant can improve prognosis.
- Published
- 2010
18. [Eosinophilic gastroenteritis in a boy].
- Author
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Shi PP and Zhang JJ
- Subjects
- Child, Eosinophilia drug therapy, Gastroenteritis classification, Gastroenteritis drug therapy, Humans, Male, Eosinophilia diagnosis, Gastroenteritis diagnosis
- Published
- 2010
19. [Eosinophilic cardiomyopathy in a child].
- Author
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Zhuo ZH, Wang HL, Luo Q, Zhang Q, and Gao TZ
- Subjects
- Cardiomyopathies therapy, Child, Eosinophilia therapy, Humans, Male, Cardiomyopathies diagnosis, Eosinophilia diagnosis
- Published
- 2009
20. [Cytogenetic study on eosinophilia].
- Author
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Zhang Y, He Q, Huang XJ, Jiang H, Yang SM, Lu J, Qing YZ, Shi Y, Dang H, Qiu JY, and Lu DP
- Subjects
- Adolescent, Adult, Aged, Aged, 80 and over, Cytogenetic Analysis, Diagnosis, Differential, Eosinophilia diagnosis, Eosinophilia pathology, Female, Humans, Hypereosinophilic Syndrome diagnosis, Hypereosinophilic Syndrome pathology, Male, Middle Aged, Young Adult, Chromosome Aberrations, Chromosomes, Human, Pair 16 genetics, Eosinophilia genetics, Hypereosinophilic Syndrome genetics
- Abstract
The aim of study was to investigate the importance of chromosome aberration in differential diagnosis of eosinophilia and the chromosomal aberrations involved in patients with clonal eosinophilia. 65 cases of eosinophilia were collected and chromosome specimens of bone marrow cells were prepared by 24-hour culture, and G-banding technique was used for karyotyping. The results showed that out of 65 cases, chromosome 16 inversion was detected in 9 patients suspected as M(4Eo), and among the other 56 cases, 5 were detected with chromosomal aberrations (8.9%). Combining clinical, hematological and cytogenetical data, the 5 patients were diagnosed as acute myeloid leukemia with eosinophilia, chronic eosinophilic leukemia, 8p11 myeloproliferative syndrome, chronic myeloid leukemia in acute phase and acute myeloid leukemia-M(4Eo) respectively. The detected chromosomal aberrations were +14, t (5; 12) (q31; p13), t (8; 9) (p11; q32), t (9; 22) (q34; q11) and inv (16) (p13 q22). In conclusion, cytogenetical detection is very important in differential diagnosis of clonal eosinophilic disorders and chronic eosinophilic leukemia, which is suggested to be done routinely in clinic.
- Published
- 2007
21. [Childhood eosinophilic gastroenteritis in a case].
- Author
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Li ZL, Liu XL, Kou XJ, and Wei L
- Subjects
- Child, Colitis diagnosis, Colon, Sigmoid pathology, Diagnosis, Differential, Eosinophilia diagnosis, Female, Gastroenteritis complications, Gastroenteritis pathology, Humans, Sigmoid Diseases complications, Sigmoid Diseases pathology, Diarrhea etiology, Eosinophilia complications, Gastroenteritis diagnosis, Sigmoid Diseases diagnosis, Sigmoidoscopy
- Published
- 2005
22. [Sputum induction and its application in assessing airway inflammation].
- Author
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Liu YH and Dong JC
- Subjects
- Eosinophilia diagnosis, Humans, Respiratory Function Tests, Asthma diagnosis, Pulmonary Disease, Chronic Obstructive diagnosis, Sputum cytology
- Published
- 2004
23. [Eosinophilic cystitis in children:a report of six cases and review of literature].
- Author
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Cai B, Xie H, Xu MS, Geng HQ, Zhang ZD, Li ZC, Liu GH, and Chen F
- Subjects
- Adolescent, Child, Child, Preschool, Cystitis diagnosis, Diagnosis, Differential, Eosinophilia diagnosis, Female, Humans, Male, Cystitis therapy, Eosinophilia therapy
- Abstract
Objective: Eosinophilic cystitis is a very rare tumor-like inflammatory disease especially in children. It can involve any portion of the bladder and interfere with its function. Here we present 6 pediatric cases and review the literature., Methods: Six children, with mean age of 8.3 years, were referred to our clinic. Their major complaints included voiding urgency, frequency, dysuria, enuresis, intermittent hematuria and abdominal pain. Ultrasound, CT scan and voiding cystourethrogram (VCUG) showed diffuse thickening of bladder wall and a filling-defect lesion. They all suggested the possibility of bladder tumor. The final diagnosis of eosinophilic cystitis was made by cystoscopic tissue biopsy or open surgery. Patients underwent bladder autoaugmentation, mass resection or mere oral administration of corticosteroid and antibiotics respectively., Results: 5 among 6 patients were followed up for 5 - 28 months. Their voiding complaints and image changes gradually disappeared. Up to now, there is no relapse., Conclusions: The clinical presentation of eosinophilic cystitis includes irritative voiding symptoms, hematuria and abdominal pain. Tumor-like changes could be found in the imagination examinations. A biopsy is mandatory to establish the diagnosis. Treatment in general varies from the removal of the antigenic stimulus, if identifiable, to administration of corticosteroid and antibiotics. When patients fail to respond to the medication treatment, the opening operation could be required.
- Published
- 2003
24. [A case of eosinophilic meningitis caused by cysticercosis of brain].
- Author
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Huang YL and Chen WX
- Subjects
- Animals, Antibodies, Helminth blood, Antibodies, Helminth cerebrospinal fluid, Child, Preschool, Eosinophilia cerebrospinal fluid, Eosinophilia diagnosis, Female, Humans, Meningitis cerebrospinal fluid, Meningitis diagnosis, Neurocysticercosis drug therapy, Neurocysticercosis parasitology, Taenia immunology, Eosinophilia etiology, Meningitis etiology, Neurocysticercosis complications
- Published
- 2003
25. [A case with disseminated eosinophilic fasciitis and myositis].
- Author
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Mao Q, Luo FP, and Wang XZ
- Subjects
- Child, Eosinophilia diagnosis, Eosinophilia therapy, Fasciitis diagnosis, Fasciitis therapy, Humans, Male, Myositis diagnosis, Myositis therapy, Eosinophilia complications, Fasciitis complications, Myositis complications
- Published
- 2003
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