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Arming at the coexistence dilemma of inventory overhang and shortage of different maintenance equipment supply nodes, a steady-state coefficient of a supply node has been described with which contains inventory level, the support degree between nodes each other, the demand status of the area guaranteed by the node and the cost of risk when the demand cannot be met. The steady-state coefficient of the inventory network was calculated on the base of all of support nodes. The active adjustment is carried out flowing the corresponding algorithm according to the gap between the steady-state coefficient and the threshold which has been set before. The scientific, automatic and intelligent level of equipment adjustment can be greatly improved, consequently the success rate of maintenance support is improved if the passive stock adjustment is combined because of out of stock at the same time.

Objective To determine bone mineral density (BMD) and the level of serum uric acid in senile patients with type 2 diabetes mellitus (T2DM) through cross-sectional observation, and to investigate the relationship between them. Methods A total of 254 senile T2DM patients, who were definitely diagnosed and over 60 years old, were selected into this study. The clinical data were collected. BMD of all the patients was detected. The patients were divided into 3 groups according to T values; normal bone mass group (n = 89), osteopenia group (n =86), and osteoporosis group (OP, n =79). In addition. they were also groupd on the basis of serum uric acid levels; high uric acid group (blood uric acid ⩾420 μmol/L) and normal group (blood uric acid < 420 μmol/L). Results The serum uric acid and BMD of each part in senile male T2DM patients were higher than those in female patients, while the incidence of OP was lower than that in female patients, and the difference was significant (P < 0.05). In male patients, the serum uric acid level was positively correlated with BMD of LI -4 and the Wards triangle (r = 0.366, P = 0.009; r = 0.367, P = 0.008). But no significant correlation was in female patients (P > 0.05). In high uric acid group, the serum uric acid level was negatively correlated with BMD of the femoral neck and the greater trochanter (r = -0.374, P = 0.025; r = -0.535, P = 0.001). However, in normal uric acid group, the serum uric acid level was positively correlated with BMD of the femoral neck (r = 0.212, P = 0.010). Conclusion BMD in senile T2DM patients was affected by gender and serum uric acid levels. The high - normal levels of serum uric acid are useful to stable BMD. [ABSTRACT FROM AUTHOR]

Objective: To explore the role of ompT gene in uropathogenic E. coli (UPEC) CFT073 strain in urinary tract infection (UTI)., Methods: An ompT deletion mutant (COTD) was generated by λ Red recombineering in the UPEC CFT073 strain, which was characterized by PCR and sequencing. C57B/L6 mouse models of acute UTI with the mutant and wild-type strains were established to compare the colonization abilities of the two strains in the bladder. The adhesion of CFT073 mutant to human unthelial 5637 cells was also investigated in vitro., Results: PCR and DNA sequencing confirmed the loss of ompT gene in the mutant COTD. The in vitro adhesion rate of the mutant strain COTD to 5637 cells was (6.7±2.2)%, significantly lower than that of (8.3±1.9)% of the wild-type strain (P<0.05). In the murine models of acute UTI, the mutant strain showed a mean colonization number of about (17±8)×10⁴ cfu, which was significantly lower than that of (7∓2)×10⁵ cfu of the wide-type CFT073 strain (P<0.05)., Conclusion: OmpT gene can be involved in the colonization of UPEC in the bladder tissue and plays an important role in the pathogenesis of UPEC-induced UTI.