1. [Individual allergens as risk factors for asthma and bronchial hyperresponsiveness in Chinese children].
- Author
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Chen YZ, Ma Y, Wang HY, Wang HJ, Zhao J, Cao L, Li S, Wong GW, Zhong NS, Fok TF, and Lai CK
- Subjects
- Allergens classification, Asthma etiology, Bronchial Hyperreactivity etiology, Child, China, Hong Kong, Humans, Risk Factors, Skin Tests, Surveys and Questionnaires, Allergens immunology, Asthma immunology, Bronchial Hyperreactivity immunology
- Abstract
OBJECTIVE This study aimed to determine the relationship between individual allergens with current wheezing and bronchial hyperresponsiveness (BHR) in schoolchildren from three chinese cities: Beijing, Guangzhou and Hong Kong. METHODS Community-based random samples of 10-yr-old schoolchildren from the 3 cities were recruited for study using the International Study of Asthma and Allergies in Childhood (ISAAC) Phase II protocol. The subjects were studied by parental questionnaires (n = 10,902), skin-prick tests (n = 3478), and methacholine challenge tests (n = 608). RESULTS The highest prevalence rates of wheezing in the past 12 months (Beijing, 3.8%; Guangzhou, 3.4%; Hong Kong, 5.8%) and atopy (Beijing, 23.9%; Guangzhou, 30.8%; Hong Kong, 41.2%, defined as having
- Published
- 2003