Objective: To describe the characteristics of newly reported HIV/AIDS cases via non-marital or non-commercial heterosexual transmission and to find out the relative factors in Hangzhou, from 2015 to 2017. Methods: Data were collected through the national HIV/AIDS comprehensive control and prevention data system. Study subjects would include those reported HIV/AIDS cases who were residents of Hangzhou and were infected via non-marital heterosexual transmission, between January 1, 2015 and December 31, 2017. Demographic characteristics and behavioral information were collected. χ (2) test was used to compare different characteristics of the non-married heterosexual transmission subjects. Logistic regression was used to assess factors that associated with non-marital but non-commercial HIV heterosexual transmission with SPSS. 20 software used to analyze statistically. Results: Non-marital HIV heterosexual transmission accounted for 38.03% (1 393/3 663) of the total new reported HIV/AIDS cases in 2015-2017. Out of the 1 393 HIV/AIDS cases, those infected through non-marital but non-commercial heterosexual transmission accounted for 50.83% (708/1 393), and those through non-martial commercial transmission was accounted for 49.17% (685/1 393). Male to female ratio was 3.51 ∶ 1 (1 084/309). Male HIV cases reported that their major way of infection was via non-marital commercial transmission (670/1 084, 61.81%), while female patients reported the way was via non-marital non-commercial (294/309, 95.1%). Results from multivariate logistic analysis showed that the related risk factors and OR s for non-marital but non-commercial transmission appeared as: female (a OR =48.25, 95 %CI : 26.94- 88.44),<30 year olds (a OR =2.43, 95 %CI : 1.31-4.51), 30-39 year olds (a OR =1.92, 95 %CI : 1.11- 3.33), 40-49 year olds (a OR =1.80, 95 %CI : 1.08-3.00), married or unmarried ( vs. divorced or widowed, a OR =1.57, 95 %CI : 1.10-2.24; a OR =1.78, 95 %CI : 1.15-2.78), high school and above of education level ( vs. primary school and under of education level, a OR =1.82, 95 %CI : 1.18-2.80), administrative officers or employee ( vs. farmers, a OR =2.03, 95 %CI : 1.04-1.91). Number of non- marital partners less than 5 ( vs. number of non-marital partners more than 5, a OR =10.65, 95 %CI : 6.41-17.42). Conclusions: HIV/AIDS cases with non-marital heterosexual transmission accounted for considerable proportion regarding the HIV transmission in Hangzhou from 2015 to 2017. Differences were found in the following factors as non-marital and non-commercial heterosexual transmission with diverse gender, age, marital status, educational level and occupation among of the HIV/AIDS patients.