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Objective: To evaluate the inadequate diagnostic rate of ultrasound guided fine needle aspiration cytology (USFNAC) in thyroid calcified nodules., Methods: 208 thyroid calcified nodules in 202 patients were retrospective analyzed, and all of the nodules were acquired cytological diagnosis., Results: There was no significant complication in the all 208 thyroid calcified nodules. The inadequate diagnostic rate was 25.5% in thyroid calcified nodules. The inadequate diagnostic rates in micro calcifications , macro calcifications and circumjacent arc calcifications were 16.0%, 26.4% and 76.5%. The inadequate diagnostic rate in circumjacent arc calcifications were higher than those in micro calcifications and macro calcifications (P < 0.01) , and the rates were no significance in micro calcifications and macro calcifications. There was no statistical significance in different size of thyroid calcified nodules., Conclusions: The inadequate diagnostic rate in circumjacent arc calcifications was higher, and should to avoid USFNAC in these nodules.