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1. [Molecular determinants in regulating Pseudomonas aeruginosa type III secretion system--a review].

Author

Luo Q and Jin S

Subjects
Animals, Bacterial Proteins genetics, Humans, Protein Transport, Pseudomonas aeruginosa genetics, Pseudomonas aeruginosa pathogenicity, Virulence Factors genetics, Bacterial Proteins metabolism, Gene Expression Regulation, Bacterial, Pseudomonas Infections microbiology, Pseudomonas aeruginosa metabolism, Virulence Factors metabolism
Abstract

Pseudomonas aeruginosa is a Gram-negative opportunistic bacterial pathogen. Successful injection of virulence factors into host cells, evasion of phagocytosis and promotion of pathogenesis depend primarily on the function of type III secretion system (T3SS). A complex set of signaling pathways have been shown to modulate T3SS expression. In this review, a brief introduction is given on the composition, function, and molecular determinants that regulate P. aeruginosa T3SS gene expression.

Published
2008

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