1. Research Progress on Gene Polymorphisms Related to Osteosarcoma
- Author
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Peng ZHANG, Kai CHEN, Lingling HUANG, Jinyan LIU, and Wen TIAN
- Subjects
osteosarcoma ,susceptibility ,single nucleotide polymorphisms ,biomarkers ,genome-wide association study ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Osteosarcoma, which primarily affects children and adolescents, is a highly malignant bone tumor with high rates of disability and mortality. Therefore, the exploration of biological markers related to its occurrence, development, and prognosis is crucial. Genome-wide association studies have revealed the vital role of genetic polymorphisms in the pathogenesis of osteosarcoma. This study aims to provide new insights into reliable biomarkers of osteosarcoma through the analysis of the functional single-nucleotide polymorphisms of tumor-related genes.
- Published
- 2024
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