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Ten compounds were isolated from Mylabris phalerata by using preparative HPLC and column chromatography over MCI gel. On the basis of physical-chemical properties, NMR and MS data analysis, the compounds were identified as 5'-[(1 R,2 R,3 S,6R)-1-hydroxymethyl-2-methyl-3,6-epoxycyclohexane-1,2-dicarboximide]- ethyl-2'-methyl-2'-butenoate (1),cantharidin (2), cyclo-(L-Pro-L-Ala) (3), cyclo-(R-Pro-R-Leu) (4), cyclo-(S-Pro-R-Leu) (5), cyclo-(D-Pro-L-Tyr) (6), indole-3-aldehyde (7), 3-indoleacetic acid (8), valerolactam (9), and 4-hydroxyphthalid (10).Compound 1 was a new compound, and compounds 2-10 were obtained from this genus for the first time. Compounds 1-9 were subjected to cytotoxic activity on HCT-116, HepG2, BGC-823, NCI-H1650, A2780 cell lines, and only compound 2 showed inhibitory effect on all cancer cell lines., Competing Interests: The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose., (Copyright© by the Chinese Pharmaceutical Association.)

Objective: To study sesquiterpenes from the root of Chloranthus serratus., Methods: The sesquiterpenes of Chloranthus serratus were isolated and purified by various chromatographic techniques, such as silica gel, Sephadex LH-20 and preparative HPLC. The structures of these isolated compounds were identified by spectroscopic analysis., Results: Ten sesquiterpenes were isolated and identified as follows: 1β, 8β-dihydroxy-eudesman-4 (15), 7 (11) -dien-8α, 12-olide (I), curcolonol (II), 4β, 8β-dihydroxy-5α (H) -eudesm-7 (11) -en-8, 12-olide (III), 1β, 8,β-dihydroxy-eudesman-3, 7 (11) -dien-8α, 12-olide (IV), multistalactone E (V), zedoarofuran (VI), 8β,9α-dihydroxylindan-4(5), 7(11) -dien-8α,12-olide(VII), serralactone A (VIII), 8-epi-ivangustin (IX), and chloranthalactone E (X )., Conclusion: Compounds I, II, IV - VII, IX and X are isolated from Chloranthus serratus for the first time.

Objective: To study the chemical constituents from the root of Polygala tenuifolia., Methods: Silica gel,Sephadex LH-20 and ODS chromatographic techniques were used to study the chemical constituents of Polygala tenuifolia, and the chemical structures were elucidated by application of spectral data., Results: Eight-compounds were obtained and their structure were identified as 7-hydroxy-1-methoxy-2,3-methylenedioxyxanthone(1), 1, 7-dihydroxy-2, 3-dimethoxyxanth one(2), 1,3,6-trihydroxy-2, 7-dimethoxyxanthone(3),7-hydroxy-1,2, 3-trimethoxyxanthone(4), 1,2,3,6, 7-pentamethoxyxanthone(5), 1,3, 7-trihydroxy-2, 6-dimethanoxyxanthone (6),7-hydroxy-1-methoxyxanthone(7) and 1,7-dihydroxy-3,4-dimethoxyxanthone(8)., Conclusion: Compounds 1,6,7 and 8 are isolated from Polygala tenuifolia for the first time.

Objective: To study the chemical constituents of the root bark of Tripterygium hypoglaucum., Methods: Column chromatography was used to separate the chemical constituents. The structures were determined by application of spectroscopic (NMR, MS) and chemical methods., Results: Eleven compounds were isolated and identified as 4'-0-(-) methylepigallocatechin (1),3,4-dimethoxyphenyl-beta-D-glucopyranoside (2), 3,4,5-trimethoxyphenyl-f-D-glucopyranoside (3), (2R,3R)-3,5,7,3',5'-pentahydroxyflavan (4), 2-O-deacetyleuonine (5), tripfordine C (6), peritassine A (7) hypoglaunine C (8), wilfortrine (9), wilforgine (10) and wilfordine (11)., Conclusion: Compounds 1-6 are isolated from this plant for the first time.

Aim: To study the chemical constituents of the roots of Chloranthus henryi., Methods: The constituents of Chloranthus henryi were separated with various chromatographic techniques. structures were elucidated by physico-chemical properties and spectral data., Results: Eight compounds were isolated from Chloranthus henryi. They were identified as curcolonol (I), zedoarofuran (II), shizukanolide E (III) , skimmin (IV), calucanthoside (V), chloracoumarin (VI), beta-sitosterol (VII), daucosterin (VIII)., Conclusion: Chloracoumarin (VI) is a new compound and characterized as 6,8-dimethoxy-7-O-[beta-D-apiofunanosyl(l --> 3 )-D-glucopyranosyl]-2H-benzopyran-2-one. Compounds I, II were isolated from Chloranthus henryi for the first time.