1. [Chemical Constituents from Oldenlandia diffusa].
- Author
-
Ma H, Li FL, Wang F, Guo Q, Cao GS, and Yang PM
- Subjects
- Cyclopentane Monoterpenes, Glucosides, Iridoids, Lignans, Pyrans, Chromatography, High Pressure Liquid, Oldenlandia
- Abstract
Objective: To study the chemical constituents of water extracted fraction from Oldenlandia diffusa., Methods: The compounds were isolated and purified by column chromatography on macroporous resin,silica gel,MCI gel,Sephadex LH-20,ODS medium pressure liquid chromatography and RP-semi-preparative HPLC. The structures of compounds were elucidated on the basis of physicochemical and spectral analysis., Results: 16 compounds were isolated from the water extract of Oldenlandia diffusa,and their structures were identified as asperuloside( 1),deacetyl asperuloside( 2),geniposide( 3),10-dehydrogeniposide( 4),daphylloside( 5),diffusoside A( 6),diffusoside B( 7),coniferin( 8),scandoside methyl ester( 9),acetyl scandoside methyl ester( 10),deacetylasperulosidic acid methyl ester( 11),gardenoside( 12),galioside( 13),galioside 10-acetate( 14),loliolide( 15) and( +)-neo-olivil( 16),respectively., Conclusion: Compounds 3,8 and 14 ~ 16 are obtained from Oldenlandia diffusa for the first time.
- Published
- 2016