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A γ′ phase strengthened NiCoCrFeAlTiMoW alloy was prepared in a vacuum arc melting furnace, and X-ray diffractometer (XRD), scanning electron microscope (SEM), energy dispersive spectrometer (EDS) and tensile testing machine were used to investigate the coarsening behavior and the evolution law and mechanism of mechanical properties of the γ′ phase after 200 h long-term aging at 750, 850 ℃ and 950 ℃.The results show that γ′ phase remains spherical during the aging process when the aging time is extended, γ′ phase size gradually increases and the solidification phenomenon occurs at 750, 850 ℃ and 950 ℃. The alloy has a high diffusion activation energy with a value of 357 kJ/mol.This is mainly due to the fact that the matrix is a high entropy solid solution with complex composition, and the diffusion of Al and Ti atoms in the matrix becomes difficult due to the hysteresis diffusion effect. The yield strength of the alloy gradually increases after aging at 750 ℃, the yield strength after aging at 850 ℃ first increases and then decreases, and gradually decreases after aging at 950 ℃. The change in the yield strength of the alloy is caused by the increase in the size of the γ′ phase, which leads to a shift in the precipitation strengthening mechanism of the alloy.

Objective To analyze the anxiety status and influencing factors among biosafety laboratory (BSL) personnel in Xinjiang. Methods In 2021, a total of 8 500 BSL workers from disease control centers, hospital laboratories, and other related departments in 106 counties of Xinjiang, selected by a cluster sampling method, were surveyed with the Self-Rating Anxiety Scale (SAS). The logistic regression model was used to analyze the possible influencing factors for anxiety. Results A total of 7 924 valid questionnaires were collected, with an effective recovery rate of 93.2%. The anxiety detection rate was 34.93% (2 768/7 924), including 19.95% mild anxiety, 8.99% moderate anxiety, and 5.99% severe anxiety. The logistic regression analysis showed that the females had a higher risk of developing anxiety than the males (OR = 1.418, P < 0.05). Compared with those aged < 24, those aged 30 - 44 and over 50 were more likely to develop anxiety (OR = 1.298, 1.482, P < 0.05). Compared with the unmarried, the married had an increased risk of developing anxiety (OR = 1.159, P < 0.05). Compared with those without asking for leave, those asking for leave had an increased risk of developing anxiety (OR = 1.228 - 4.405, P < 0.05). Compared with those with working time ≤ 5 years, those with working time over 6 years had an increased risk of developing anxiety (OR = 1.444, 2.002, P < 0.05). Compared with experimental technicians, logistics and engineering personnel had an increased risk of developing anxiety (OR = 1.280, P < 0.05). Compared with workers with a fixed-day shift, shift workers had an increased risk of developing anxiety (OR = 2.051, P < 0.05). The workers with coronary heart disease and peptic ulcer had an increased risk of developing anxiety (OR = 1.848, 2.951, P < 0.05) compared with workers without this disease. Compared with those with technical secondary school and below, those with the bachelor degree or above had a reduced risk of developing anxiety (OR = 0.685, P < 0.05). Compared with those who did not exercise, those who exercised weekly had a reduced risk of developing anxiety (OR = 0.708 - 0.775, P < 0.05). Compared with those with poor sleep quality, those with good sleep quality had a reduced risk of developing anxiety (OR = 0.201, P < 0.05). Compared with those with an average monthly income of less than 3 000 yuan, those with a monthly income of more than 4 000 yuan had a reduced risk of developing anxiety (OR = 0.685 - 0.771, P < 0.05). Conclusions The anxiety incidence rate of BSL workers in Xinjiang was high, and the influencing factors were multifaceted. The evaluation and intervention of their anxiety should be paid attention to. Relevant departments should intervene at multiple levels to improve the occurrence of employees' anxiety. [ABSTRACT FROM AUTHOR]

Objective To explore the relationship between occupational stress, sleep quality, and quality of life among biosafety laboratory (BSL) staff in Xinjiang. Methods In July 2022, the cluster sampling method was used to select 1 980 on-duty staff from biosafety laboratories in various regions of Xinjiang, and a questionnaire survey was conducted through the Questionnaire Star online survey platform with the Effort-Reward Imbalance Scale, the Pittsburgh Sleep Quality Index, and the World Health Organization Quality of Life Scale. Intergroup comparisons were made to evaluate the correlation between occupational stress, sleep quality, and quality of life. A structural equation model was established with AMOS 21.0 software to analyze the mediating effect of sleep quality between occupational stress and quality of life. Results A total of 1 591 valid questionnaires were collected, with an effective recovery rate of 80.4%. The detection rate of occupational stress was 87.0%, while the detection rate of sleep disorders was 37.1% in biosafety laboratory staff. The median (25%, 75% percentile) of quality of life scores was 56.76 (49.81, 62.12) points. The quality of life scores of staff with 30-39 years old, the bachelor's degree, 11-20 years of work experience, the intermediate professional title, and no exercise per week were lower (P < 0.05). The scores of occupational stress and sleep quality were negatively correlated with the quality of life scores (rs = - 0.435, - 0.441, P < 0.01), and occupational stress was positively correlated with the scores of sleep quality (rs = 0.371, P < 0.01). The results of the structural equation model showed that both occupational stress and sleep quality had direct effects on quality of life (the standardized path coefficients were - 0.17 and - 0.52, respectively (P < 0.01). Occupational stress could indirectly affect quality of life through sleep quality (β = - 0.29, P < 0.01, the mediating effect accounted for 63.0%). Conclusions The higher the level of occupational stress and the sleep quality of BSL staff, the worse their quality of life will be. The biosafety laboratory arranges work tasks rationally, builds a good working system, and improves its quality of life. [ABSTRACT FROM AUTHOR]

This paper designs and realizes the control system of remote control of building windows with mobile phone APP. The system is composed of a mobile phone terminal, a master controller and an electric window opener. The mobile terminal sends a control instruction to the main controller, and the master controller controls the electric window opener to realize the opening, the suspension and the closing of the window. The design of the system realizes the real-time display of the state and position of the window on the mobile phone interface, and provides a practical technical scheme for conveniently and remotely controlling the window switch through the mobile phone.

Objective To investigate the current situation and the relevant affecting factors of job burnout among underground coal mine workers in order to protect the physical and mental health of coal miners. Methods A total of 950 underground workers in a coal mine in Xinjiang were investigated by cluster sampling. The effort-reward imbalance questionnaire (ERI) and Maslach burnout inventory (MBI) were used to investigate occupational stress and job burnout. A multiple linear regression model was used to analyze the related factors of job burnout. Results Totally 887 valid questionnaires were collected, and the effective recovery rate was 93.4% . The main occupational hazard factors in the production process of the coal mine were coal dust, silica dust, toxic and harmful gases, noise, hand-transmitted vibration, heat stress, power frequency electric fields, ultraviolet radiation, and so on. Among the 887 subjects, 860 were men; 764 (86.13%) had high occupational stress, while 839 (94.59%) had job burnout, including 388 (43.74%) with mild, 392 (44.19%) with moderate, and 59 (6.65%) with high burnout. The results of multivariate regression analysis showed that the total scores of job burnout for the workers with work time of 15-30 years or more than 30 years were increased by 2.259 and 5.642 points, respectively, compared with the workers with work time less than 15 years (P < 0.05). The total score of job burnout increased by 3.080 points among shift workers compared to fixed day shift workers (P < 0.05) and increased by 3.106 points among workers in the ERI > 1 group compared with workers in the ERI ≤ 1 group (P < 0.05). Conclusions The situation of occupational stress and job burnout among underground coal mine workers was severe. Managers in the coal mining industry should regularly monitor the occupational psychological status of these workers and take positive measures to reduce the occurrence of occupational stress and job burnout and, finally, to protect their health. [ABSTRACT FROM AUTHOR]

Objective: To explore the relationship between occupational stress and psychological disorder among oilfield workers., Methods: In 2013, 1485 psychological normal oilfield workers using the stratified cluster sampling in Xinjiang Autonomous Region were investigated, and the follow-up was conducted in 2015. Occupational stress and mental health status were assessed by questionnaire for the occupation stress and self-rating symptom., Results: The people with mental disorder was 556, the incidence rate was40. 29%. The level of occupational stress level low-high group( RR = 2. 689, 95% CI1. 342-5. 391) and middle-high group( RR = 2. 878, 95% CI 1. 205-6. 875) of mental disorder were higher than the low-low group, the level of Personal Strain Questionnaire low-middle group( RR = 2. 500, 95% CI 1. 700-3. 763) and low-high group( RR =3. 907, 95% CI 1. 955-7. 651) and middle-middle group( RR = 2. 141, 95% CI 1. 016-4. 512) of mental disorder were higher than low-low group. Without drinking( RR =0. 779, 95% CI = 0. 622-0. 976) was protective factor for mental disorders., Conclusion: Occupational stress and drinking are the risk factors of mental disorder, it is more practical to multiple measurement of the psychological disorder of occupational stress exposure than single one.

Objective: To explore the effects of occupational stress on neurotransmitters in petroleum workers., Methods: 178 petroleum workers with the length of service ≥ 1 year were recruited to the subjects by the questionnaire of OSI-R. The levels of 5-hydroxy tryptamine (5-HT), norepinephrine (NE), neuropeptide Y (NPY) and substance P (SP) in serum were measured. The subjects were classified into 3 groups according to the scores of occupational stress., Results: The levels of 5-HT NE and SP for over 15 working years were higher than those of less than 15 years (P < 0. 05). There were differences (P < 0. 05) on 5-HT, NE, NPY and SP in different occupational stress degree groups, multiple comparison showed high. occupational stress group was higher than those of low occupational stress group. Multivariate correlation analysis showed that the occupational stress and sleep quality component scores correlated positively with the 5-HT, NE and SP (P < 0. 05) and correlated inversely with NPY in petroleum workers (P < 0. 05)., Conclusion: Occupational stress in petroleum workers is correlated with serum monoamine and neuropeptides neurotransmitters, and it may affect serum levels of monoamine and neuropeptides neurotransmitters.

Objective: To provide scientific basis for further intervention, the association between occupational stress and job burnout among oil field workers of Xinjiang was discussed., Methods: A random sample and research on Xinjiang oil-field outdoor workers who will finish occupation Stress Inventory-Revised questionnaire and Maslash Burnout Survey., Results: The scoring of each OSI-R dimension and each MBI dimension varied significantly between different individual characterizations (age, gender and education). Multiple linear regression analysis showed: occupation task, physical strain, work environment, subjective support, self health care are the main factors influencing occupation burnout., Conclusion: Different individual characteristics effect the occurrence of occupation stresses and job burnout, reduce the occupation task, strengthen social support and self health care consciousness, strive to build and improve the enterprise culture atmosphere can prevent occupation burnout.

Objective: To use primary and middle schools teacher as samples to preliminarily build the mental work stress effect evaluation system, providing the methological platform for the research on the stress effect mechanism and mental workers interference measures., Methods: 851 teachers in primary and middle schools were selected with randomly stratified cluster methods. Use ISTA 6.0 and Life Events Evaluation Table to measure the stress factors, and use Work Tension Reaction Questionnaire, Symptom Self-Evaluation Table Questionnaire, and General Happiness Sensing Table to measure psychological stress reaction, blood sugar and blood fat, blood cortical, ACTH, nerve behavior function, for measuring physiological stress reaction. The Comprehensive Working Ability Index Table to measure working ability. And then use the mathematical model to build the mental workers stress effect evaluation system. And apply the simple random sampling method to select 400 environmental protection workers to perform cross effect validation., Results: The model fits relatively well (RMSEA = 0.100, GFI = 0.93, NNFI = 1.00, CFI = 1.00) and conforms with the theory, reflecting the loads of the indice, such as, working stress reaction, psychological stress reaction, physiological stress reaction and working ability, are relatively high. At the same time, the stress reaction of those 4 dimensions can fit the 2-grade factor (stress effect) very well. The physiological stress reaction is negatively correlated (P < 0.05) with the working stress reaction, psychological stress reaction, working ability decrease, while is positively correlated (P < 0.05) with the working stress, psychological stress reaction, physiological stress reaction and working ability decrease. The social support is the protection factor for working stress, psychological stress reaction, physiological stress reaction and working ability decrease (gamma(s) are -0.55, -0.77, 0.73, -0.79, respectively, P < 0.05). While working stress factors, social life stress factors and dangerous individual characters are the risk factors (P < 0.05) for working stress, psychological stress reaction, physiological stress reaction increase and the working ability decrease. The utilization of the environment protection workers further validates this model., Conclusion: It conforms with the theory to evaluate the mental workers stress effects from the 4 dimensions, working stress, psychological stress reaction, physiological stress reaction, and working ability. And these 4 dimensions influence each other, and also are mutually different. The working and social life stress factors influence the stress effects with certain degrees. This evaluation model can tentatively be the methodological basis for the mental workers occupational stress evaluation.

Objective: To study the effect of 2,2',4,4'-tetrabrominated diphenyl ethers (BDE-47) on the expression change of TRalpha1, TRbeta1 at both mRNA and protein levels., Methods: C57BL/6 mice were divided randomly into 4 groups and administrated with corn oil, 0.5, 5 and 50 mg/kg/BW BDE-47 for 4 days through intraperitoneal injection respectively. GAPDH selected as internal standard, real time quantitative RT-PCR and Western blot were employed to detect the mRNA levels and protein of TRalpha1 and TRbeta1 in livers., Results: Compared with the control group, the mRNA levels of TRalpha1 and TRbeta1 were up-regulated in the medium and high BDE-47 dose groups (P < 0.05). The protein level of TRalpha1 significantly up-regulated while TRbeta1 was significantly down-regulated., Conclusion: BDE-47 could change the expression of TRalpha1 and TRbeta1 in the mRNA and protein levels in liver.

Objective: To investigate the effects and of toxicity mechanism of 2,2',4,4'-TETRABDE (BDE-47) on TT3, TT4 and TSH in C57BL/6 mice., Methods: C57BL/6 mice were divided randomly into 4 groups, and given with corn oil (control group) and 1 micromol/(kg x d), 10 micromol/(kg x day) and 100 micromol/(kg x day) BDE-47 for 4 days through intraperitoneal injection respectively. After collecting the bloods, livers and thyroids, the T3, T4 and TSH levels of serum were detected by electro chemiluminescenc (ECLI), thyroid peroxidase (TPO) activities in thyroid by guaiacol method and type-I deiodinase (DI) in liver by CHOPRA method., Results: Compared with the control group, the level of TT4 decreased significantly in the three BDE-47 dose groups, TT3 in the medium and high dose groups decreased significantly, and the activities of DI increased in the medium and high dose groups significantly (P < 0.05), whereas TSH level in serum and activity of TPO in thyroid in the three dose groups weren't statistically significant comparing with control group., Conclusion: BDE-47 could affect the homeostasis of thyroid hormone system, and activity of type-I deiodinase (DI) in liver being changed might be the one of toxicity mechanisms.

Objective: To determination total phenolics content of raspberry different polar solvent extracts was measured by Folin-Ciocalteu method., Methods: Red raspberry fruits were extracted with 95% ethanol, defatted with petroleum ether, and then partitioned with petroleum ether, ethyl acetate and butanol successively. Total phenolic content of each part was measured by Folin-Ciocalteu method and calculated as gallic acid equivalents (GAE). Stability of the method were assayed with RSD (relative standard deviation). Antioxidant activities of the different extractions were evaluated with DPPH* and OH* scavenging assay., Results: (1) The method had high quality of precision, stability, repetition rate. (2) Total phenolic contents were varied from GAE 10.56 mg/g to GAE 96.76 mg/g as gallic acid equivalent, and ethyl acetate extracts had the highest total phenolic content (GAE 96.76 mg/g). (3) The crude extracts and different soluble fractions showed good antioxidative activities., Conclusion: Raspberry could be good resource of natural antioxidant.

Objective: To explore the relationship between the polymorphism of vitamin D receptor (VDR) and genetic polymorphism in Han, uygur and Kazak child in China., Methods: The VDR genotyping was determined by PCR-RFLP in 469 Han, 443 Uygur and 516 Kazak child from Xinjiang province. The correlation between the polymorphism of VDR and blood lead levels were explored., Results: The frequencies of the allele BsmIB and BsmIb in Han child were 6% and 94%, and in Uygur were 18% and 82%, in Kazak were 43% and 57% respectively. Statistic correlation between the distribution of VDR-BsmI alleles and the blood lead level was found in Han and Uygur., Conclusion: The genetic susceptibility of VDR polymorphism to lead toxicity may exhibit in a lead dose-dependent manner.

Objective: To study the relationship between occupational stress and psychological health state among oil workers., Methods: 1,230 oil workers in 122 work types of oil industry were selected and written occupational stress questionary(OSQ) and symptom check list (SCL-90)., Results: Petroleum workers' psychological health states were poor with increasing occupational stress degree. The scores in physical symptoms(1.87 +/- 0.80, 1.72 +/- 0.70), depression(1.74 +/- 0.76, 1.62 +/- 0.67), horror(1.48 +/- 0.65, 1.39 +/- 0.55) in the high and medium stress group were obviously higher than those in low stress group(1.55 +/- 0.61, 1.43 +/- 0.54, 1.28 +/- 0.46, respectively, P < 0.05). The score of mood state in the high and medium stress group was obviously higher than that in low stress group(P < 0.05). Psychological health states and mood state in the petroleum workers with short service length are significantly poorer than that with long service length(P < 0.01)., Conclusion: Occupational stress should affect psychological health state of petroleum workers.