Search

Manganese is an indispensable trace element in the human body, pivotal in development, reproduction, metabolism, neurological functions, and antioxidative processes. Recently, the important role of manganese in host immunity has been increasingly recognized and valued. Serving as a damage-associated molecular pattern, manganese exhibits robust immune activation capabilities. Manganese ions stimulate cells to generate numerous cytokines, including type Ⅰ interferons, regulating both innate and adaptive immune responses, thus showing great potential in adjuvant and tumor immunotherapy. In this review, the homeostatic regulation of Manganese and its role in the immune response are summarized. Subsequently, it extensively explores diverse applications of manganese and its derivatives in immune adjuvants and tumor immunotherapy, and looks ahead to their future prospects.

Manganese dioxide in pyrolusite was directly reduced to manganese sulfate by high-temperature roasting with ammonium sulfite as reducing agent, so as to achieve efficient extraction of pyrolusite. The effects of mass ratio of ammonium sulfite to pyrolusite, roasting temperature and time, leaching temperature and time on the extraction rate of manganese were investigated, and the optimum process conditions were determined. The results show that the optimal conditions are the mass ratio of ammonium sulfite to pyrolusite of 0.75:1, roasting temperature of 500 °C, roasting time of 1.5 h, leaching temperature of 25 °C, leaching time of 30 min. Under the conditions, the leaching rate of manganese and iron is about 93% and about 9.5%, respectively. The extraction effect of manganese is good. [ABSTRACT FROM AUTHOR]

Copyright of Technology of Water Treatment is the property of Technology of Water Treatment Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Hydrometallurgy of China is the property of Hydrometallurgy of China Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The study was to establish a method for uncertainty evaluation of Cu, Fe and Mn content in feed by flame atomic absorption spectrometry, and to reflect the confidence and accuracy of the measurement. The sources of uncertainty in the determination process were analyzed, and the uncertainty components were quantified. Then the contents of copper, iron and manganese in the feed were calculated by mathematical model to synthesize the extended uncertainty. The results showed that the contents of Cu, Fe and Mn in diets were (11±2) mg/kg, (214±10) mg/kg and (92±4) mg/kg, respectively. The uncertainty was an expanded uncertainty with a factor of 2 and a confidence level of 95%. Sample digestion, sample solution concentration determination and content repeatability measurement are the main factors affecting the measurement uncertainty of copper, iron and manganese in feed. Special attention should be paid to the sample pretreatment process and the preparation of standard working solution. To improve the detection accuracy, the concentration of the sample should be adjusted to the middle of the standard curve. [ABSTRACT FROM AUTHOR]

The cheese rod-like magnesium oxide (C-MgO) was obtained by pyrolyzing basic magnesium carbonate precursor with rod shape synthesized from magnesium sulfate and ammonium bicarbonate in solution in the absence of surfactants. The surface morphology, phase composition, functional groups and other physical and chemical properties were analyzed using SEM, XRD, IR, TG characterization. The adsorption efficiency and mechanism of manganese by C-MgO were investigated from wastewater. The results show that C-MgO has a supremely high adsorption capacity of 5793 mg/g of manganese, which is higher than the reported adsorbents. In addition, kinetic results show that the C-MgO can achieve rapid removal of manganese from wastewater with low dosage of 0.08g/L. The results of adsorption mechanism study showed that the main adsorption mechanism of C-MgO for manganese is magnesium oxide protonation, manganese hydroxide coordination, magnesium manganese complexation, during which the MgO transformed into MgMn2O4 by chemisorption. The fixed bed adsorption experiment proves that C-MgO has a good potential application prospect. Therefore, this investigation provides a facile strategy for preparing high-performance cheese-like magnesium oxide, which can achieve low-cost and efficient removal of manganese from wastewater. [ABSTRACT FROM AUTHOR]

Aiming at the problems such as long production cycle, low utilization rate of carbon dioxide and difficult to meet the standard requirements of battery grade lithium carbonate produced by traditional carbonization decomposition method, the preparation of battery grade lithium carbonate by sodium carbonate--shear carbonization--ion exchange--heating decomposition process was studied using low-grade leachite ore as raw material. The results show that the removal rates of calcium, magnesium and manganese are 97.26%, 81.82% and 95.73 %, respectively, under the conditions of 30 °C, liquid volume/solid mass ratio of 25/1, carbon dioxide input rate of 0.5 L/rnin and shear speed of 6 000 r/min. The shear assisted carbonization method can significantly improve the carbonization reaction rate, shorten the reaction time, save more than 70% of CO2, and is more conducive to the production of battery grade lithium carbonate. The prepared lithium carbonate can meet the standard of battery grade lithium carbonate. [ABSTRACT FROM AUTHOR]

China as a biggest producer of electrolytic manganese is in the imperative to ameliorate the soil pollution which caused by electrolytic manganese waste residue. In this study, a survey was undertaken at a electrolytic manganese residue storage in Caixi Village of the Yuping Dong-minority Autonomous County under the jurisdiction of Tongren City of Guizhou Province, where the largest reserve of manganese ore resources in China is situated. To understand the characteristics of soil pollution, the speciation distribution of heavy metals (incl. Mn, Zn, Pb, Ni, Cr and Cd), and ecological risk of heavy metal contamination of the soil around the electrolytic manganese residue storage were analyzed by wet digestion and BCR sequential extraction. Mn, Pb and Cd, inter alia, had caused the severest impacts on the environmental quality of soil: Mn concentration was in the range of 356~14 915 mg/kg, with an average of 3 828 mg/kg, being 4.8 times higher than the background value of the soil in Guizhou; and the average concentrations of Pb and Cd were 3.1 and 40.2 times, respectively, higher than the "risk screening values of the National Standard for Farmland Soil". As to the heavy metal speciation, six species of heavy- metal were mainly composed of migratory dissolved weak acid, and the content of dissolved fraction of weak acid of Mn and Cd in soil increased as the distance got closer towards the residue storage dam (P<0.05). According to the analytic result by using the common Kriging spatial interpolation, there existed a kind of moderate spatial correlation among the content of Mn, Cd, Zn, Pb and Ni; in addition, the content of Mn and Cd, among others, were randomly affected by the pollution of human activity considerably; and the spatial distribution of concentrations of Mn and Cd in general showed the higher in the east and lower in the west parts of the area being investigated, and the high values of Mn and Cd concentrations were found mostly near the dam of the waste residue storage; and the results of principal component analysis (PCA) indicated that Mn, Cd and Pb were mainly resulted from the pollution of electrolytic manganese residue, while the contamination sources of Ni and Zn could be traced to the nearby agricultural activities and industrial production. Furthermore, Cr was mainly affected by the geological background factors, the highest potential ecological risk level belonged to the soils in proximity to the waste residue storage, and particularly, the contribution ratio of Cd was the highest (91%). [ABSTRACT FROM AUTHOR]

A manganese and manganese dioxide co-tank electrodeposition process was developed to investigate the effect of four factors by using a one-factor test, enhance cathode and anode current efficiencies, and reduce energy consumption. Response surface methods was adopted to examine the relationship among the four variables temperature, anode and cathode electrodeposition efficiency, compartment sulfuric acid concentration, and cathode ammonium sulfate concentration. A quadratic regression fitting model was developed to determine the optimal electrolysis conditions. A cathode ammonium sulphate concentration of 107. 11 g/L, an anode sulphuric add concentration of 2. 8 mol/L, a septum chamber concentration of 0. 516%, and a temperature of 40. 2 &lowbar; were the bes--optimized factor combinations leading to the best cathode current efficiency of 84.79% and anode current efficiency of 68.43% .The study showed that ammonium sulphate concentration and temperature significantly impacted cathode electrolysis efficiency. In contrast, sulphuric acid concentration and temperature had the most significant impact on anode electrolysis efficiency. The electrolytic manganese metal is securely deposited, and the electrolytic manganese dioxide particles are unholy. [ABSTRACT FROM AUTHOR]

A new three-dimension manganese(II) metal-organic framework [Mn2(5-ana)4 (H2O)]n (namely Mn-MOF) has been successfully constructed by the reaction of 5-aminonicotinic acid (5-Hana) and MnCl2 using solution method at room temperature. The structure and properties of Mn-MOF were characterized by X-ray single-crystal diffraction, X-ray powder diffraction, elemental analysis, infrared spectroscopy, thermogravimetric analysis, ultraviolet-visible spectra and luminescent spectra. Structural analysis reveal that the as-synthesized complex crystallized in the monoclinic system and feature a binodal (2,8)-connected coordination network. The [Mn2(CO2)2 (H2O)] dimeric unit acts as 8-connected node and 5-ana-ligand acts as 2-connected node. Electrostatic potential (ESP) on molecular van der Waals surface analysis of 5-ana- ligand shows that the first reactive site exists in the surface close to the oxygen atoms of carboxyl group with the ESP global minimum of -143.37 kcal·mol-1. The second and third reactive sites exist in the nitrogen atoms of pyridine ring and amino, respectively. Mn-MOF displays good thermal stability at room temperature. Fluorescence spectroscopy measurement reveals that the complex shows emission maximum at 402 nm upon 256 nm light excitation. More importantly, Mn-MOF exhibits sensing selectivity for Fe3+ by fluorescence quenching with the quenching efficiency up to 98.71%, which makes it as a potential luminescent sensor for analyzing Fe3+ in aqueous solution. [ABSTRACT FROM AUTHOR]

The leaching of manganese from electrolytic manganese residue with sulfuric acid was studied, and the process parameters were optimized by single factor test and orthogonal test. The phase, structure, morphology and leaching kinetics of electrolytic manganese residue before and after leaching were analyzed. The leaching model was established and the leaching mechanism was explored. The results show that under the optimal conditions of particle size of 200 mesh, stirring speed of 400 r/min, leaching temperature of 95 °C, sulfuric acid concentration of 1. 5 mol/L, leaching time of 120 min and liquid volume/solid mass ratio of 11/1, the leaching rate of Mn can reach 97. 90%. Manganese leaching kinetics accords with the liquid-solid shrinkage model and is controlled by chemical reaction. In the process of manganese leaching, the leaching rate of Mn can be improved by controlling the liquid volume/solid mass ratio and temperature. [ABSTRACT FROM AUTHOR]

BACKGROUND: Based on the superior properties of ceramics, bioceramic materials are widely used in bone transplantation and tissue engineering. However, it still faces the problems of low mechanical strength and single biological function, which cannot fully meet the clinical application of bone defect repair. OBJECTIVE: To summarize the research status of bioceramic scaffolds and the effect of manganese doping on the performance of ceramics. METHODS: Chinese and English search terms were “manganese, microelements, ceramic biomaterials, hydroxyapatite, tricalcium phosphate, 3D printing, bone tissue engineering”. Searches were carried out on CNKI, WanFang, PubMed, and Web of Science databases. Relevant articles published from January 1968 to September 2022 were retrieved. According to the inclusion criteria, 84 articles were finally included. RESULTS AND CONCLUSION: Manganese, as an important locally delivering therapeutically active ion, has a positive stimulating effect on cell function and bone formation. The doping of manganese elements can greatly improve the mechanical properties of ceramic scaffolds, further enhance the osteogenic induction ability of ceramic materials, and endow the scaffolds with additional antibacterial properties. (2) Based on manganese-containing bioceramics, the need for bone defect repair was further met through coating, covalently binding bioactive peptides and regulating the valence of doping elements. (3) It began to gradually change from single-element doping to multi-element doping, and strive to give the stent more characteristics. (4) Doping of manganese elements is an effective modification treatment method. Manganese-containing bioceramics have a good application prospect in the repair of fractures and bone defects by combining advanced material manufacturing technology and the excellent biological activity of manganese. [ABSTRACT FROM AUTHOR]

Manganese is one of the essential trace elements in the process of animal growth and develop‐ ment, which affects animal immunity, metabolism, reproduction and bone development, and participates in the metabolism of various substances as an enzyme composition and enzyme activation factor in ani‐ mals. In this paper, the circulation process of manganese in ruminants and its influence on sheep physiol‐ ogy and production were reviewed, in order to provide some theoretical reference for the application of manganese in sheep production. [ABSTRACT FROM AUTHOR]

In this study, zeolite and bentonite were used as the base materials to prepare barrier. Through mechanics experiment, penetration experiment, microscopic characterization, adsorption experiment, centrifuge model experiment and numerical simulation experiment, the control effect of barrier on ammonia nitrogen pollution in manganese slag storage yard was discussed. The results showed that the optimal mass ratio of zeolite and bentonite was 3:2, and the mass of cement accounted for 50% of the mass ratio of the whole system. The addition of zeolite improved the anti-penetrability performance and mechanical properties of the barrier material, the minimum hydraulic conductivity reached 2.049x10-10 m/s, and the maximum compressive strength reached 3.36 MPa. The zeolite made the internal structure of the barrier material became uniform and dense, which significantly improved the adsorption capacity of the barrier material to ammonia nitrogen. The adsorption process of ammonia nitrogen by the barrier material was more consistent with the quasi-second-order kinetic model and the Freundlich model, and the adsorption process was endothermic. With the penetration of ammonia nitrogen solution, the hydraulic conductivity of barrier material gradually decreased and became stable. Visual MODFLOW numerical model was used to simulate the process of ammonia nitrogen migration in groundwater, and the barrier was still not penetrated after 5 000 d. The zeolite-bentonite barrier showed excellent effect in preventing and controlling ammonia nitrogen pollution in manganese slag yard. [ABSTRACT FROM AUTHOR]

The removal of fluorine from high fluorine manganese sulfate solution by lanthanum oxide was studied. The effects of initial solution pH, the amount of lanthanum oxide, reaction temperature, reaction time and stirring speed on the removal rate of fluorine were investigated. The defluorinated products were characterized by XRD and EDS. The results show that for the high fluoride manganese (II) sulfate solution with the fluoride ion mass concentration of 1 260 mg/L, the fluoride mass concentration is reduced to 10 mg/L and the fluoride removal rate is 99.93% under the conditions of initial solution pH = 3, lanthanum oxide amount of three times of the theoretical amount, reaction temperature of 55 °C, reaction time of 40 min, and stirring speed of 250 r/min. The fluorine mass concentration in manganese sulfate products is less than 14 mg/L, which can meet the requirements of preparing high-purity manganese (II) sulfate. This method has remarkable effect on defluorination of high fluoride manganese sulfate solution. [ABSTRACT FROM AUTHOR]

Parkinson's disease (PD) is one of the hotspots in the research field of neurodegenerative diseases, and its pathogenesis is still controversial. Trace metal elements play an important role in normal growth and development of the human body. Metal ions can cross the blood-brain barrier and enter the brain, leading to α-synapnuclein aggregation, mitochondrial dysfunction, and degeneration of dopaminergic neurons, and then inducing the occurrence of PD. This article mainly reviewed the potential mechanisms of metal elements in PD, discussed the role of metabolic imbalance of common trace metals (copper, iron, manganese, and zinc) in PD, and put forward new insights into the treatment of PD.

【Objective】The study aimed to explore the remediation effect and physiological response of moso bamboo (Phyllostachys pubescens)to manganese(Mn) contaminated soil.【Method】The physiological response and heavy metal enrichment characteristics of moso bamboo were analyzed by measuring the botanical traits, photosynthetic parameters and chlorophyll fluorescence parameters of moso bamboo at different Mn stress concentrations (0, 1 000, 2 000 and 4 000 mg/kg)in soil.【Result】Under 4 000 mg/kg Mn stress, the plant height, leaf length, leaf width and basal diameter of moso bamboo decreased by 22.6%, 25.9%, 21.3% and 26.7%, respectively, compared to the control, and the water utilization of moso bamboo leaves decreased significantly by 30.6 perccentage pints, the photochemical quenching index (qP) and nonchemical quenching index (qN) decreased by 29.8% and 20.7%, respectively. Furthermore, peroxidase (POD) activity and peroxidase (CAT) activity were reduced by 39.4% and 22.6%, respectively. Under Mn stressed soils supplemented with 0, 1 000, 2 000 and 4 000 mg/kg concentrations, the average above ground(stem and leaves)Mn enrichment of moso bamboo was 1 098.6, 2 336.4, 3 530.9 and 5 370.4 mg/kg, respectively, with Mn transfer coefficients of 1.59, 3.83, 3.56 and 4.17, respectively.【Conclusion】Mn stress at high concentrations has an inhibitory effect on the botanical traits of the moso bamboo, but the moso bamboo is still able to grow and has a good enrichment capacity for Mn stressed soils. It can be used as a new plant for manganese stressed soils. This study provides some reference value for future research in the field of heavy metal pollution control and phytoremediation.

Copyright of Asian Journals of Ecotoxicology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Asian Journals of Ecotoxicology is the property of Gai Kan Bian Wei Hui and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Molecular Science is the property of Journal of Molecular Science Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Acta Geoscientica Sinica is the property of Acta Geoscientica Sinica Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BackgroundLead and manganese are heavy metal pollutants widely existing in the environment, which can accumulate in the human body through the food chain, exert neurotoxicity, and cause neurodegenerative disorders. Especially in early childhood, the developing blood-brain barrier and nervous system are highly susceptible to environmental chemical pollutants. Most of the previous studies focused on the toxic effects of single heavy metal such as lead or manganese, while the studies on combined toxic effect are still scarce, and involved mechanisms are still unclear. c-Jun N-terminal kinase (JNK) is involved in neuronal development and regeneration, and some studies have found that JNK is involved in lead or manganese induced neurotoxicity. Its role in the toxicity of combined lead and manganese is unknown. ObjectiveTo understand the neurodevelopmental toxicity mechanism and to observe changes of JNK expression in zebrafish induced by combined lead and manganese exposure at environmentlly low concentrations. MethodsZebrafish embryos within 2 h post fertilization (hpf) were divided into four groups: control group, lead exposure group (0.1 mg·L−1 lead acetate), manganese exposure group (0.3 mg·L−1 manganous chloride), and lead-manganese combined exposure group (0.1 mg·L−1 lead acetate +0.3 mg·L−1 manganous chloride) and exposed to lead or/and manganese at designed levels for 7 d. Spontaneous movements and motor locomotion were observed, and mortality rate were calculated. The changes of JNK mRNA expression in zebrafish were evaluated. ResultsThe experimental results showed that no significant effect of lead or/and manganese on spontaneous movements and mortality rate was found in zebrafish compared with the control group (P＞0.05). The results of locomotion analysis showed that compared with the control group, the activity counts and activity distance of zebrafish in the manganese exposure group were slightly increased (P＜0.01); the activity counts and activity distance of zebrafish in the lead exposure group were reduced by 50% and those in the lead-manganese exposure group were reduced by 80% (P＜0.01). Compared with the lead exposure group, the activity counts and activity distance of zebrafish in the lead-manganese combined exposure group decreased significantly by 60% (P＜0.05). The real-time quantitative PCR results showed that the JNK mRNA expression level was significantly increased in the lead-manganese combined exposure group compared with the control group(P＜0.01). ConclusionLead exposure combined with manganese exposure at environmentlly low concentration can induce neurodevelopmental toxicity to zebrafish. JNK may be involved in neurodevelopmental toxicity induced by the combined exposure to lead and manganese.

In order to solve the serious problems of F−、Fe2+ and Mn2+ in underground water of mining area, the serpentine loaded hydroxy-apatite (Srp/HAP) composite adsorbent was prepared by wet chemical coprecipitation method, and the simultaneous removal of fluorine, iron and manganese in underground water was studied. Through batch experiment and CCD response optimization experiment, the effects of dosage, reaction time and pH on the removal efficiency of F−、Fe2+ and Mn2+ were investigated, and a quadratic regression model with the removal rates of F−、Fe2+ and Mn2+ as response values was established. Srp/HAP adsorption and regeneration experiments were carried out to explore its reusability. The results show that the optimal reaction conditions of Srp/HAP treatment of complex water samples with mass concentrations of F−、Fe2+ and Mn2+ of 5 mg/L, 20 mg/L and 5 mg/L respectively are as follows: When 3.64 g/L water sample was added, the reaction time was 120.47 min and the pH value was 6.3, the corresponding removal rates of F−、Fe2+ and Mn2+ were 98.23%, 99.9% and 99.7% respectively. The effluent shall meet the requirements of the 《Standards for drinking water quality》(GB5749—2006).The adsorption process of F−、Fe2+ and Mn2+ by Srp/HAP was well fitted by the CCD optimized experimental model. The absolute error between the predicted value and the experimental value is less than 5%, which proves that the experimental model is reliable. After five times of regeneration, the removal rates of F−、Fe2+ and Mn2+ by Srp/HAP composite particles decreased by 16.13%, 10.5% and 15.4%, respectively, less than 20%. Srp/HAP composite particles can be used as an excellent adsorbent for the treatment of groundwater containing fluoride, iron and manganese ions.

BackgroundNeurotransmitter secretion disorder induced by chronic manganese poisoning has always been one of the important causes of body injury, but the mechanism of neurotransmitter secretion disorder caused by manganese is not clear at present. ObjectiveTo investigate the effects of presynaptic membrane intracellular protein 13-1 (Munc13-1) and synapse fusion protein binding protein 18-1 (Munc18-1) on dopamine secretion dysfunction induced by manganese chloride (MnCl2) in human neuroblastoma (SH-SY5Y) cells. MethodsA SH-SY5Y cell model induced by MnCl2 was established. Cell viability was measured by MTT assay. Four experimental groups were set up: control group and low-, medium-, and high-dose manganese groups (0, 100, 200, and 400 μmol·L−1 MnCl2). They were treated with corresponding doses of MnCl2 for 24 h. The secretion of dopamine was measured by enzyme-linked immunosorbent assay. The mRNA expression of Syntaxin-1 was detected by real-time quantitaive PCR. Total cell proteins were extracted, and the protein expression levels of Munc13-1, Munc18-1, and Syntaxin-1 were detected by Western blotting. The correlations of MnCl2 exposure and dopamine secretion with the protein expressions of Munc13-1 and Munc18-1 were also analyzed by Pearson correlation. ResultsCompared with the control group, the cell viability rate decreased gradually with the increase of manganese exposure concentration, and the difference between the medium- and the high-dose manganese groups was statistically significant (P0.05). Compared with the control group, the protein expression of Munc13-1 decreased and that of Munc18-1 increased with the increase of manganese concentration (P

Copyright of Chinese Journal of Cancer Biotherapy is the property of Editorial Office of Chinese Journal of Cancer Biotherapy and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Geology & Exploration is the property of Geology & Exploration Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

【Objective】The study aimed to explore the remediation effect and physiological response of moso bamboo （Phyllostachys pubescens）to manganese(Mn) contaminated soil.【Method】The physiological response and heavy metal enrichment characteristics of moso bamboo were analyzed by measuring the botanical traits, photosynthetic parameters and chlorophyll fluorescence parameters of moso bamboo at different Mn stress concentrations （0, 1 000, 2 000 and 4 000 mg/ kg）in soil.【Result】Under 4 000 mg/kg Mn stress, the plant height, leaf length, leaf width and basal diameter of moso bamboo decreased by 22.6%, 25.9%, 21.3% and 26.7%, respectively, compared to the control, and the water utilization of moso bamboo leaves decreased significantly by 30.6 perccentage pints, the photochemical quenching index (qP) and nonchemical quenching index (qN) decreased by 29.8% and 20.7%, respectively. Furthermore, peroxidase （POD） activity and peroxidase （CAT） activity were reduced by 39.4% and 22.6%, respectively. Under Mn stressed soils supplemented with 0, 1 000, 2 000 and 4 000 mg/kg concentrations, the average above ground（stem and leaves）Mn enrichment of moso bamboo was 1 098.6, 2 336.4, 3 530.9 and 5 370.4 mg/kg, respectively, with Mn transfer coefficients of 1.59, 3.83, 3.56 and 4.17, respectively.【Conclusion】Mn stress at high concentrations has an inhibitory effect on the botanical traits of the moso bamboo, but the moso bamboo is still able to grow and has a good enrichment capacity for Mn stressed soils. It can be used as a new plant for manganese stressed soils. This study provides some reference value for future research in the field of heavy metal pollution control and phytoremediation. [ABSTRACT FROM AUTHOR]

Low grade manganese oxide ore is not suitable for direct acid leaching and traditional fire reduction technology' and can not be efficiently used as resources. Therefore it is of great significance to extract manganese from low grade manganese oxide ore by efficient reduction. The research progress of wet reduction technology of manganese oxide ore Is reviewed and the advantages and disadvantages of acid add-on method' ferrous sulfate method' hydrogen peroxide method' microbial leaching method' biomass reduction leaching method and sulfur dioxide reduction leaching method are emphatically summarized. The development direction of wet manganese extraction is prospeced. [ABSTRACT FROM AUTHOR]

Manganese plays an important physiological role in the organism, and excessive manganese exposure can cause impairment of neurological and reproductive functions. Gonadotropin-releasing hormone secreted by the hypothalamus acts as an initiator to regulate reproductive functions, such as gonadal development, onset of puberty, and gonadal hormone release. But the mechanism by which manganese damages the hypothalamus leading to abnormal gonadotropin-releasing hormone release is still unclear yet. Kisspeptin, prostaglandin E2, and nitric oxide may act as stimulators to increase the release of gonadotropin-releasing hormone, while the stimulatory or inhibitory effect of γ-aminobutyric acid on the release of gonadotropin-releasing hormone is controversial. Based on current research, manganese has been less studied with Kisspeptin, and studies with prostaglandin E2, nitric oxide, and γ-aminobutyric acid mainly focused on inflammation, oxidative stress, and neurotransmitter transmission. Therefore, taking Kisspeptin, prostaglandin E2, γ-aminobutyric acid, and nitric oxide as the breakthrough points, this paper introduced the mechanism of manganese affecting the release of gonadotropin-releasing hormone in the hypothalamus through the above four pathways, and proposed that the abnormal release of gonadotropin-releasing hormone in the hypothalamus may be one of the mechanisms by which manganese regulates reproductive function, providing a new direction for the prevention and treatment of manganese-induced reproductive damage in the future.

BackgroundManganese (Mn) is one of the environmental factors of Parkinson's disease (PD), and long-term exposure to Mn can cause nerve damage. It is important to explore the common mechanism of neurotoxic effects of Mn and neurodegenerative diseases (NDD), especially PD, for early diagnosis of the disease. ObjectiveTo comprehensively analyze the core messenger RNA (mRNA)-microRNAs (miRNAs) co-expressed in frontal cortex of NDD patients and neuronal cells exposed to Mn via bioinformatics, and to reveal the potential common mechanism between Mn-induced neurotoxicity and NDD, especially PD. MethodsDifference of the mRNAs from frontal cortex of NDD patients (GSE150696) and human neuroblastoma (SH-SY5Y) cells exposed to Mn were analyzed by R software; Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analysis was performed on the overlapping differentially expressed genes (DEGs). The miRNAs were predicted using the miRNet database, mRNA-miRNA interactions were identified by the starBase and miRTarBase databases, and mRNA-miRNA regulatory networks were constructed with Cytoscape software. The core miRNAs associated with PD (GSE77667) were incorporated into Weighted Gene Co-Expression Network Analysis (WGCNA) and the mRNA-miRNA regulatory network was comparatively analyzed. ResultsA total of 34 overlapping DEGs were identified in the frontal cortical of NDD patients and the neuronal cells exposed to Mn, mainly enriched in interleukin-17 (IL-17) signaling pathway, cyclic adenosine monophosphate (cAMP) signaling pathway, and primary immunodeficiency. Based on the results of database prediction, 52 miRNAs with 71 pairs of interaction relationships were finally included to construct the miRNA-mRNA regulatory network. Six core miRNAs were screened by WGCNA: hsa-let-7i-5p, hsa-mir-155-5p, hsa-mir-219-2-3p, hsa-mir-221-3p, hsa-mir-485-3p, and hsa-mir-509-3-5p, among which hsa-let-7i-5p interacted with the target gene FBXW2 and hsa-mir-155-5p interacted with the target gene CCL2. The results of the KEGG analysis indicated that CCL2 was closely related to the IL-17 signaling pathway. ConclusionThere are similar molecular regulatory mechanisms involved in the neurotoxicity of Mn and NDD, and the IL-17 signaling pathway may play a role in Mn-related NDD through CCL2 and hsa-mir-155-5p.

The discovery of Santonggou manganese deposit is an important breakthrough in manganese prospecting in East Kunlun. The detrital zircon from two siltstone samples of Santonggou manganese deposit were used for LA-ICP-MS U-Pb dating. The detrital zircon U-Pb ages are ranging from(1 497±17)Ma to(427±4)Ma, with two peaks of 441 and 473 Ma, respectively. The youngest detrital zircon age is(427±4)Ma, indicating the age of Santonggou manganese deposit is later than 427 Ma. The age peaks of detrital zircon are consisting with Early Paleozoic Naji Tal Group, and indicate that the detritals provenance are the middle strata of Naji Tal Group. The Re-Os isochron age of black shale from Santonggou manganese deposits are(387.4±6.2)Ma, indicating that the age of burial diagenesis is Middle Devonian, and the initial precipitation of manganese is earlier. Based on isotopic dating results, the sedimentary age of Santonggou manganese deposit is limited in Late Silurian-Middle Devonian. The relationship between the mineralization of Santonggou manganese deposit and the subduction of Proto-Tethys ocean is discussed based on the main view about genesis of Early Paleozoic marine sedimentary manganese deposit. It is considered that the subduction and closure of Proto-Tethys ocean in Early Paleozoic is the main reason for the mineralization of Santonggou manganese deposit, and the metallogenic age of Santonggou manganese deposit is basically consistent with the closure time of Proto-Tethys ocean. [ABSTRACT FROM AUTHOR]

Copyright of Inorganic Chemicals Industry is the property of Editorial Office of Inorganic Chemicals Industry and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Hydrometallurgy of China is the property of Hydrometallurgy of China Editorial Office and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Coal Science & Technology (0253-2336) is the property of Coal Science & Technology and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

The ferrovanadium slag sample was fused with sodium carbonate-boric acid at high temperature, then acidified with hydrochloric. Vanadium 310.230 nm, iron 259.940 nm, manganese 257.610 nm and phosphorus 213.618 nm were selected as the analytical lines. The matrix matching method was used to eliminate the influence of matrix effect, the determination method of vanadium, iron, manganese and phosphorus contents in ferrovanadium slag by alkali fusion-inductively coupled plasma atomic emission spectrometry was established. The results showed that the linear correlation coefficients of calibration curves were all higher than 0.999, the limit of detection for vanadium, iron, manganese and phosphorus was 0.0076 μg/mL, 0.0093 μg/mL, 0.0065 μg/mL and 0.0051 μg/mL, respectively. Two ferrovanadium slag certified reference materials were determined according to the experimental method, the relative standard deviations(RSD, n=8) were less than 3.9 %.

Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Nonferrous Metals (Mining Section) is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Journal of Henan Agricultural Sciences is the property of Editorial Board of Journal of Henan Agricultural Sciences and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

BACKGROUND: Metal elements play an important role in the human body. In recent years, the application of metal elements in biomaterials has attracted attention, and its functions and effects are being rapidly explored and broadened. Compared with the metal elements that have been studied more in recent years, such as magnesium and zinc, manganese is a rising star in the field of biomaterials research. OBJECTIVE: To summarize and review application status and existing problems of manganese in biomaterials. METHODS: The first author searched CNKI, Wanfang, ScienceDirect, and PubMed databases by computer to retrieve all relevant articles published from February 2010 to February 2021. The Chinese search terms were “manganese, biomaterials, biomedical metallic materials, ceramic biomaterial, nanomaterial, biopolymer material, bone tissue engineering, drug delivery, cancer therapy”, and the English search terms were “manganese, biomaterials, alloy, degradable metals, corrosion, biomedical metallic materials, ceramic biomaterial, nanomaterial, biopolymer material, bone tissue engineering, drug delivery, cancer therapy”. Finally, 72 included articles were summarized. RESULTS AND CONCLUSION: (1) The current research found that the introduction of manganese into biomaterials can significantly improve the mechanical properties and corrosion resistance of biomaterials, and effectively improve the biocompatibility, bone formation and antibacterial properties of biomaterials, indicating that the incorporation of manganese ions as functional ions into biological materials has good research value. (2) The current research on manganese ions in biomaterials mainly focuses on in vivo and in vitro experiments. The existing studies have shown that combining manganese ions with collagenhydroxyapatite scaffolds can promote osteogenesis of bone marrow mesenchyme stem cells in vitro and regeneration of new bone in mouse skull defects, and further enhance the osteoinductivity. (3) In view of the excellent properties of manganese, it can have broad application prospects in medical metal materials, bone tissue engineering materials, drug delivery, and tumor treatment. It is expected to provide a new direction for the basic and clinical applications of manganese-related biomaterials in the future. [ABSTRACT FROM AUTHOR]

Copyright of Mining & Metallurgy (10057854) is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Copyright of Chinese Journal of Inorganic Analytical Chemistry / Zhongguo Wuji Fenxi Huaxue is the property of Beijing Research Institute of Mining & Metallurgy Technology Group and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

To investigate the combined effect of manganese exposure and noise on welding workers' hearing loss due to the use of electrodes containing manganese. Methods A total of 198 noise -exposed workers from an automobile manufacturing company were selected and divided into two groups, namely the pure noise exposure group (n = 66) and the welding operation group (n = 132). Pure tone audiometry and urine manganese measurement were performed on all workers; the manganese concentration and noise level at the workplaces were measured, and the results of pure tone audiometry and noise-induced hearing loss detection between these two groups were compared. Results There was no statistical difference in age and noise exposure time between these two groups (P > 0.05); the pure tone thresholds at 2, 3, and 4 kHz in the welding operation group were higher than those in the pure noise exposure group (P < 0.01); 35 cases of noise-induced hearing loss were detected in the welding operation group, with a detection rate of 26.5%; eight cases of noise -induced hearing loss were detected in the pure noise exposure group, with a detection rate of 12.1%, and the difference was statistically significant (P < 0.01). Conclusions Manganese exposure due to manganese-containing welding operations may have a combined effect with noise to cause noise-induced hearing loss. [ABSTRACT FROM AUTHOR]

The multi metal cobalt residue produced by zinc hydrometallurgy is treated by primary sulfuric acid leaching and secondary high cobalt residue neutralization. The leachate with high cobalt content is successively treated by hydrogen peroxide oxidation to remove iron,zinc powder replacement to remove cadmium, nickel removal reagent to remove nickel, sodium persulfate selective oxidation to remove manganese, and sodium persulfate oxidation to deposit cobalt, to realize the separation and recovery of cadmium, cobalt, nickel and zinc in the residue. The results show that under the optimal acid leaching conditions of sulfuric acid concentration of 150 g/L, temperature of 80 ℃ leaching time of 120 min, cadmium and nickel in the leaching solution can be removed to less than 0. 1 mg/L, the content of cadmium in the cadmium residue is as high as 57. 61%, the content of nickel in the nickel residue is 10. 74%, the rate of cobalt precipitation by sodium persulfate is 99. 98%, and the content of cobalt in the cobalt residue is 49. 75%. The liquid after cobalt precipitation can be returned to the zinc hydrometallurgy production system to recover metal zinc and realize the separation and recovery of metal resources in the residue. [ABSTRACT FROM AUTHOR]