1. [Relaxation mechanism of smooth muscle cells and its relationship with penile erection].
- Author
-
Zhao H and Jiang R
- Subjects
- Carbon Monoxide physiology, Erectile Dysfunction physiopathology, Humans, Hydrogen Sulfide metabolism, Male, Muscle Contraction, Muscle, Smooth, Nitric Oxide physiology, Potassium Channels, Calcium-Activated physiology, Receptors, Estrogen physiology, Receptors, Purinergic P2Y physiology, Sulfur Dioxide metabolism, Erectile Dysfunction etiology, Myocytes, Smooth Muscle physiology, Penile Erection physiology
- Abstract
The contractile and diastolic function of smooth muscle cells (SMCs) is closely related to penile erection and erectile dysfunction (ED). In addition to nitric oxide (NO), carbon monoxide (CO), and hydrogen sulfide (H2S), sulfur dioxide (SO2), estrogen receptor (ER), P2Y receptor, perivascular tissue (PVT), and calcium activated potassium channel (Kca) are found to be involved in the relaxation of SMCs. This review updates the mechanisms of the relaxation of SMCs and its relationship with ED.
- Published
- 2016