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The "chimney rain" problem can effectively be solved by adding a secondary dehydration device inside the chimney with wet flue gas desulfurization (FGD) direct-discharged measures in coal fired power station. In order to analyze the changes of outlet moisture content and internal flow field, and to optimize the structure of device to match the dehydration capacity and working resistance, a computational fluid dynamics (CFD) method was adopted to simulate the internal flow field of the chimney. Results show that after installing a secondary dehydration device the outlet moisture ratio decreases from 111 mg/m³ to 52 mg/m³; the working resistance increases in an allowable range, from 195 Pa to 699 Pa, which is below 1 200 Pa;the outlet velocity raises from 17.3 m/s to 17.6 m/s. The smoke spirals up along in wall, not along central zone ; the optimum angle of the whirl board is 42 degrees. Through the comparative analysis of actual and simulation results, the effectivity of the device and the feasibility of optimum angle were verified, and the basic laws and characteristics curves of internal flow field were also obtained. [ABSTRACT FROM AUTHOR]

To analyze the relationship between hepatitis B virus (HBV) DNA load and serum alanine aminotransferase (ALT) level and to investigate the reason that ALT level changes in patients with HBV infection. Methods ALT level (dependent variable) and HBV DNA load (independent variable) were subjected to curve fitting using SPSS 16.0 to establish a curve regression equation and analyze the curve regression equation. Results A power model was established by software analysis, with the following results: R² =0. 107, F = 85. 887, P = 0. 000, b0 = 47. 785, b1 =0. 075, b2 = 0. The curve analysis showed that as the HBV DNA load increased, the ALT level kept rising, but at a decreasing rate ; within a certain range, the increase in HBV DNA load led to little change in ALT level, which was infinitely close to a certain value. Conclusion ALT level is correlated with HBV DNA load, but HBV DNA may not be the most direct cause of change in ALT level. [ABSTRACT FROM AUTHOR]

Objective The aim of this study was to evaluate the efficacy and side effects of sacubitril/ valsartan in the treatment of patients with chronic kidney disease (CKD) at stage 5 with resistant hypertension, and to explore the cardiovascular benefits and security of medical in the patients. Methods Patients with CKD5 resistant hypertension diagnosed and treated in the First Affiliated Hospital of Guangxi Medical University from September 2020 to March 2022 were selected and divided into the observation group (treated with routine treatment of kidney disease at end-stage and sacubitril/valsartan ) and control group (include droutine treatment of renal disease at end-stage and ACEI or ARB drugs) according to treatment strategy. The patients in both two groups were treated with adequate dialysis treatment and conventional drug treatment of renal disease at end-stage. The patients were followed up for at least 3 months, the clinical efficacy of three months after treated with sacubitril/valsartan was observed, and the efficacy indicators and security indicators and adverse cardiovascular events were observed, the occurrence of adverse effects during the period of drug use were compared with the control group. Results A total of 110 patients were included in this study and there were 55 cases in each group.There were no significant differences in gender, age, age of dialysis, etiology, dialysis mode and blood pressure between the two groups (P > 0.05). The Systolic blood pressure (SBP), diastolic blood pressure (DBP), b-type urinary natriuretic peptide precursor (Pro-BNP) and cardiac function grade in the observation group after treatment was significantly decreased compared with before treatment. The left ventricular ejection fraction (LVEF) and the ratio of LVEF < 50% in the observation group was significantly reduced after treatment (P < 0.05 ). SBP, DBP and Pro-BNP decreased 3 months after treatment compared with the baseline before treatment, and improved significantly in the first month after treatment (P < 0.05). The decrease of DBP and BNP before and after treatment was significantly different between the two groups, and the decrease of DBP and BNP was more significant in the observation group(P < 0.05). The difference of LVEF and left ventricular end diastolic diameter (LVEDD ) between the two groups before and after treatment was statistically significant, and the improvement was more obvious in the observation group (P < 0.05). There were no significant differences in the safety indicators of serum potassium, estimated glomerular filtration rate (eGFR) and liver function between two groups before and after treatment (P > 0.05). In terms of adverse reactions, only 1 case in the control group developed hyperkalemia within 3 months of follow-up, and no hypotension or other adverse reactions occurred in the two groups. Conclusions The treatment of patients with CKD stage 5 hypertension with sacubitril/ valsartan has obvious cardiovascular benefits. Sacubitril/Valsartan has efficacy in lowering blood pressure, improving cardiac function and reducing volume load, with less adverse events and higher safety than control group. [ABSTRACT FROM AUTHOR]

Probiotics can improve the intestinal flora structure of host, improve the digestion and absorption of nutrients, enhance the body immunity and promote the healthy growth of animals and improve performance. The paper reviews the biological functions of probiotics and their application in chicken production, to provide reference for the for the application of probiotics in chicken breeding. [ABSTRACT FROM AUTHOR]