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Accomplishment of the gradual strategy of the administrative reform in China relies on the system transformation, institution improvement and technology innovation of local government. As an important carrier of the transformation of government functions and reform of greater part system, Administrative Service Center of local government has made beneficial exploration in simplifying the process of administrative approval, enhancing the credibility and responsiveness of the government, and constructing supply mechanism of public service with high performance. However, with the rapid spread, there are also a host of problems as ambiguous definition of the concept, unclear nature of the institution, non - uniformed administration and inadequate function play, which need to be standardized. This raises the argument on whether all the institutional system and management processes of the center should be reunified or it should maintain the status quo to encourage the independent development of a variety of forms. Standardized administration is relatively stable and more effective, and is the important foundation and the necessary premise to the healthy development of the administrative service center. Giving local government certain room for self - adjusting, self - selection and sufficient leeway to adapt to environmental changes, encouraging it to find the right position in the exploration and avoid the simplification of models, can fully mobilize the creativity and initiative of administrative service center, and made it play a more active and efficient role in the promotion of local economic development and building a harmonious society. [ABSTRACT FROM AUTHOR]

Objective: To evaluate the clinical profile of target-controlled infusion-based anesthesia using remifentanil and propofol., Methods: 16 ASA I-II patients undergoing elective laparoscopic cholecystectomy were enrolled. Remifentanil was set at 7 micrograms.L-1 as target and profol at 3 mg.L-1 throughout the whole procedure. The hemodynamics during induction of anesthesia and recovery profiles were recorded. Arterial blood samples for analysis of remifentanil were taken 15 min after infusion, 20 min after infusion and at time of emergence., Results: After induction of anesthesia, systolic blood pressure (SBP) decreased from (144 +/- 27) mm Hg to (101 +/- 18) mm Hg (P < 0.05), mean blood pressure (MBP) decreased from (102 +/- 15) mm Hg to (69 +/- 13) mm Hg (P < 0.05) and heart rate (HR) decreased from (77 +/- 14) beats.min-1 to (63 +/- 12) beats.min-1 (P > 0.05). SBP, MBP and HR remained stable after intubation for 3 min. No patient showed haemodynamic stress to tracheal intubation. Times from stopping administration of anesthetics until full spontaneous respiration, eye opening, tracheal extubation, orientation and discharging from the postanesthetic care unit (PACU) were (12 +/- 6), (9 +/- 4), (13 +/- 6), (15 +/- 5) and (19 +/- 7) min respectively. Measured drug values of remifentanil were (4.6 +/- 9.5) microgram.L-1, (6.6 +/- 11.5) microgram.L-1, (1.2 +/- 8.7) microgram.L-1 respectively., Conclusion: Remifentanil/propofol TCI-based anesthesia achieved the optimal hemodynamic stability during anesthesia induction and maintenance, and better recovery profile from anesthesia. Measured drug values of remifentanil showed a considerable interindividual variation and more lower than the set target.