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Your search keyword '"Spinal Cord Diseases metabolism"' showing total 3 results
Start Over Descriptor "Spinal Cord Diseases metabolism" Language chinese
3 results on '"Spinal Cord Diseases metabolism"'

1. [Venous congestive myelopathy: report of a case].

Author

Wei QZ, Zhao T, Li SL, Fu B, Liu JH, and Zhang ZX

Subjects
Antigens, CD metabolism, Antigens, CD34 metabolism, Antigens, Differentiation, Myelomonocytic metabolism, Arteriovenous Malformations complications, Arteriovenous Malformations metabolism, Diagnosis, Differential, Female, Glial Fibrillary Acidic Protein metabolism, Humans, Magnetic Resonance Imaging, Middle Aged, Multiple Sclerosis, Spinal Cord Diseases complications, Spinal Cord Diseases metabolism, Arteriovenous Malformations pathology, Spinal Cord Diseases pathology
Published
2012
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2. [Effect of acupotomy lysis on hypothalamic POMC mRNA and PPE mRNA expression in rats with 3rd lumbar vertebrae transverse process syndrome].

Author

Guo CQ, Cao RJ, Sun HM, Mojtabavi SJ, Ma HF, Wu HX, Xu H, Li XH, Liu NG, Zhang Y, Yue LF, Qiao JL, and Chen ZL

Subjects
Acupuncture Analgesia, Acupuncture Points, Animals, Enkephalins metabolism, Humans, Male, Pain genetics, Pain metabolism, Pro-Opiomelanocortin metabolism, Protein Precursors metabolism, RNA, Messenger genetics, RNA, Messenger metabolism, Random Allocation, Rats, Rats, Sprague-Dawley, Spinal Cord Diseases genetics, Spinal Cord Diseases metabolism, Electroacupuncture, Enkephalins genetics, Gene Expression, Hypothalamus metabolism, Lumbar Vertebrae metabolism, Pain Management, Pro-Opiomelanocortin genetics, Protein Precursors genetics, Spinal Cord Diseases therapy
Abstract

Objective: To observe the effect of acupotomy lysis (AL) on hypothalamic proopiomelanocortin (POMO) mRNA and preproenkephalin (PPE) mRNA expression in rats with the third lumbar vertebrae transverse process syndrome (TLVTPS) so as to study its underlying mechanism in relieving symptoms of lumbar muscle strain., Methods: Twenty-four SD rats were randomly divided into normal control group, model group, AL group and electroacupunture (EA) group. The TLVTPS model was established by inserting a piece of gelatin sponge into the posterior of the left 3rd lumbar vertebrae transverse process. AL and EA were applied to the left "Shenshu"(BL 23) and "Yaoyangguan" (GV 3) respectively. The POMC mRNA and PPE mRNA expression levels in the hypothalamus were detected by in situ hybridization., Results: In comparison with the normal group, the integrated optical density (IOD) values of hypothalamic POMC mRNA and PPE mRNA positive cells in the model group were increased significantly (P < 0.01); while compared with the model group, those of POMC mRNA and PPE mRNA positive cells in both left and right hypothalamus were increased further considerably in both AL and EA groups (P < 0.01). No significant differences were found between AL and EA groups in POMC mRNA and PPE mRNA expression levels (P > 0.05)., Conclusion: AL and EA therapies can increase the expression of POMC mRNA and PPE mRNA in hypothalamus in rats with TLVTPS, which may contribute to its effect in relieving pain in the treatment of lumbar muscle strain.

Published
2010

3. [Effect of acupotomy lysis on SP and CCK-8 contents in hypothalamus and spinal cord in rats with transverse process syndrome of the third lumbar vertebra].

Author

Hu B, Liu L, Guo CQ, Li XH, Sun HM, Liu NG, Lu J, Gu SZ, and Ma HF

Subjects
Animals, Electroacupuncture, Male, Random Allocation, Rats, Spinal Cord Diseases therapy, Acupuncture, Hypothalamus metabolism, Lumbar Vertebrae, Sincalide metabolism, Spinal Cord metabolism, Spinal Cord Diseases metabolism, Substance P metabolism
Abstract

Objective: To observe changes of SP and CCK-8 contents in the hypothalamus and spinal cord after performing acupotomy lysis so as to study its central analgesic effect in rats with transverse-process syndrome of the third lumbar vertebra., Methods: Twenty-eight SD rats were randomly divided into normal control group, model group, acupotomy lysis group and electroacupuncture (EA) group, with 7 cases in each one. The model of the third lumbar vertebra transverse process syndrome was established by inserting a piece of gelatin sponge into the deep subfascial part of the 3rd lumbar transverse process. Acupotomy lysis was conducted 1 time/week for 2 weeks. EA (2/100 Hz, 1-2 mA) was applied to the left "Shenshu" (BL 23)-"Yaoyangguan"(GV 3) for 20 min/time, 3 times/week and for 2 weeks. SP and CCK-8 contents in the hypothalamus and spinal cord were detected with enzyme linked immunosorbent assay (ELISA)., Results: In model group, SP and CCK-8 contents in the hypothalamus and spinal cord were increased significantly in comparison with normal control group (P < 0.01). Compared with model group, both SP and CCK-8 contents in hypothalamus and SP content in spinal cord in acupotomy lysis and EA groups were apparently lower (P < 0.01, 0.05). CCK-8 content in spinal cord in cupotomy lysis group was lower markedly than that of model group (P < 0.01), while no significant difference was found between model group and EA group in CCK-8 level in spinal cord (P > 0.05)., Conclusion: Acupotomy lysis can downregulate SP and CCK-8 contents in hypothalamus and spinal cord, which may contribute to its effect in relieving pain from transverse process syndrome of the third lumbar vertebra.

Published
2008

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